Not exact matches
«There were
several reasons why we thought phosphoarginine might be the «bacterial
ubiquitin»,» says Tim Clausen, for whom protein degradation has long been an area of intense focus.
Boston Biochem specializes in
several related product lines for
ubiquitin and
ubiquitin - like (UBL) proteins (e.g. Apg8, FAT10, ISG15, NEDD8, SUMO, UFM1) and associated enzymes, substrates, inhibitors and kits.
The tumor suppressor BAP1 associates with ASXL1 / 2 to form the core Polycomb complex PR - DUB, which catalyzes the removal of mono -
ubiquitin from
several substrates including histone H2A.
Several years later, Varshavsky showed how the individual
ubiquitin molecules hook up in these chains.