When she was 20 weeks pregnant, she learned from an ultrasound that her fetus was suffering from
severe brain abnormalities.
Mice lacking the gene develop
severe brain abnormalities.
The agency said there have been recent variations in the number of cases reported in the region and, while the level of risk is unknown, Zika virus infection during pregnancy causes severe birth defects, including microcephaly and other
severe brain abnormalities.
Not exact matches
Among the 42 Zika - infected women in the study, 12 were carrying fetuses with
severe abnormalities, including absence or withering of
brain structures, tissue death, restricted growth and, in one case, microcephaly.
Severe CTE was defined as tau clusters and several other degenerative
abnormalities affecting not only the cortex, but deeper
brain structures including the hippocampus, the amygdala, and the
brain stem.
By adjusting the levels of a key signaling protein, researchers improved motor function and
brain abnormalities in experimental animals with a form of Huntington's disease, a
severe neurodegenerative disorder.
Defects in mitochondrial DNA lead to devastating genetic diseases, with such symptoms as
brain abnormalities,
severe fatigue, blindness or defective heart function — and can be fatal.
Severe abnormalities were detected including decreased body weight, hyperactivity, abnormal anxiety responses, cognitive deficits, shortened survival and
brain atrophy (Menalled et al., SFN 2009).
«From an imaging standpoint, the
abnormalities in the
brain are very
severe when compared to other congenital infections,» report co-author Dr. Deborah Levine said in a news release from the journal Radiology, which published the findings Aug. 23.