Adapted from the best - selling fictional novel by R.J. Palacio, Jacob Tremblay plays 10 - year - old Auggie — a boy afflicted by
severe facial deformities caused by Treacher - Collins Syndrome — prompting his being homeschooled.
Chbosky attempts to spread Palacio's message of acceptance It looks like this fall will be stirring up the feels in us with Wonder, a film about a young 5th grade age boy named Auggie Pullman, played by Jacob Tremblay (The Book of Henry, Room), who has
severe facial deformities and to make matters worse he's -LSB-...]
That's what eventually seems to happen once Johansson abducts a man with
severe facial deformities and, in a weirdly touching series of scenes, shows hints of sympathy for her deeply lonely, Elephant Man - like prey.
In humans, for example, loss of ALX1 leads to
severe facial deformities.
On presentation mucoid nasal discharge with epistaxis was present bilaterally, along with
a severe facial deformity.
Not exact matches
Symptoms include dwarfism,
severe bone disease, including
facial deformity, degenerative joint disease, enlarged liver and eye cloudiness.
Dr. Romain Lambrot explained that there was an almost 30 percent increase in birth defects when the fathers had insufficient folate in their diet: «We were very surprised... We saw some pretty
severe skeletal abnormalities that included both cranio -
facial and spinal
deformities.»