Even when a condition known as
hiatal hernia is discovered, it still is not associated strongly enough with
severe reflux to be considered a sole cause.
Other heritable conditions that are related to loss of genetic diversity and inbreeding include cataract, various heart valve defects including pulmonic stenosis, hydrocephalus, cysteine urolithiasis, and
hiatal hernias; immunologic disorders that include a propensity for
severe demodectic mange indicative of immunodeficiency, allergies associated with atopic dermatitis and ear infections, and autoimmune diseases such as hypothyroidism; and cancers including glioblastoma, mast cell sarcoma and lymphoma [15, 16].