Sentences with phrase «severe hyperglycemia»

Increased glucagon appears to contribute to development of severe hyperglycemia by mobilizing hepatic stores of glucose and to development of ketoacidosis by increasing the oxidation of fatty acids in the liver.

(B) Inoculation with diabetic pancreas homogenate produced severe hyperglycemia (> 250 mg / dL) in a portion of the animals.

Further analysis revealed that the mice in Tg / Tg group, which developed severe hyperglycemia, lost > 75 % of their β cells compared with WT mice of the same strain and similar age.

Our findings demonstrate that induction of IAPP misfolding and aggregation by administration of preformed IAPP - aggregated seeds leads to the development of marked T2D - like pathology, including severe hyperglycemia, impaired glucose homeostasis, loss of β cells, and changes in islets morphology.

12 - mo - old Tg mice displayed extensive islet pathology and overt signs of T2D, including massive amyloid deposits, impaired insulin production (Fig. 1) and severe hyperglycemia (> 360 mg / dl fasting blood glucose).

Not exact matches

If your dog is experiencing a severe attack of hyperglycemia, you need to take immediate action.