Those who do not experience these early warning signs — a condition called impaired awareness of hypoglycemia — are at increased risk for
severe hypoglycemic events, during which the person is unable to treat himself or herself.
The current study enrolled 48 people who had persistent impaired awareness of hypoglycemia and experienced
severe hypoglycemic events despite expert care by a diabetes specialist or endocrinologist.
The researchers are continuing to follow participants to determine whether the benefits of restoring near - normal blood glucose control and protection from
severe hypoglycemic events will outweigh the risks associated with chronic immunosuppression.
One year after the first transplant, 88 percent of study participants were free of
severe hypoglycemic events, had established near - normal control of glucose levels, and had restored hypoglycemic awareness.
«The findings suggest that for people who continue to have life - altering severe hypoglycemia despite optimal medical management, islet transplantation offers a potentially lifesaving treatment that in the majority of cases eliminates
severe hypoglycemic events while conferring excellent control of blood sugar,» said NIAID Director Anthony S. Fauci, M.D.
Not exact matches
None of the patients were treated with insulin or had prior episodes of
severe hypoglycemia — both known risk factors for future
hypoglycemic events.