These are chronic immune disorders in which an uncontrolled response of mucosal immune cells leads to
severe inflammation in the intestine.
Not exact matches
«We were fascinated to find that, without the influence of Myb, Treg cells would allow the immune response to spin out of control, resulting
in severe inflammation pretty much everywhere — whether
in the lungs, liver,
intestine or skin,» she said.
There were no differences
in the secondary outcomes (individual components of the primary outcome, culture - proven late - onset sepsis, and necrotizing enterocolitis (
severe inflammation due to decreased blood flow that occurs
in the
intestines of premature infants)
in the adjusted analysis.
The two main types, Crohn's disease and ulcerative colitis, develop from uncontrolled
inflammation in the
intestine, which can lead to
severe diarrhea, pain, fatigue, weight loss and even death.
In severe cases, the mucus layer may not be present due to inflammation allowing bacteria in the intestine to start spreading to other parts of the body due to the intestinal permeabilit
In severe cases, the mucus layer may not be present due to
inflammation allowing bacteria
in the intestine to start spreading to other parts of the body due to the intestinal permeabilit
in the
intestine to start spreading to other parts of the body due to the intestinal permeability.
If the
inflammation of the
intestines is
severe, the neighboring liver and pancreas may also become inflamed, resulting
in increased liver enzymes and amylase (produced by the pancreas).
If allowed to progress untreated, C. difficile colitis can become
severe, and
in certain cases, the
inflammation can become so serious that part of the
intestine must be removed.