MPS IIIA is a severe, progressive disorder caused by a mutation in the SGSH gene and resulting
in severe neurological symptoms such as progressive dementia, aggressive behavior, hyperactivity, and an inability to sleep for more than a few hours at a time.
If uncontrollable seizures or
other severe neurological symptoms develop, owners may consider euthanasia as a potentially appropriate response to the condition that is causing their dogs to suffer.
Cannon's symptoms steadily worsened after employees of a medical company that had a contract with the county brushed off
his severe neurological symptoms as heat exhaustion, instructing guards to give him water and let him rest.
Fewer than 1 % of patients have
severe neurological symptoms, such as seizures, paralysis, or coma, that require hospitalization.
Cats in a hypertensive crisis (
severe neurological symptoms or sudden onset blindness) will need emergency treatment and will usually require hospitalization and careful monitoring.
Even a few licks of the stuff can cause kidney failure and
severe neurological symptoms, usually resulting in death.