This story began with a British family that had 16 members over three generations with
severe speech difficulties.
It was discovered in the 1990s in a British family, some of whom have
severe speech difficulties caused by a mutation in this gene.
Not exact matches
This report expands the phenotype of older patients with BRPS; common emerging features include
severe intellectual disability (11/12), poor / absent
speech (12/12), autistic traits (9/12), distinct face (arched eyebrows, prominent forehead, high - arched palate, hypertelorism and downslanting palpebral fissures), (9/12), hypotonia (11/12) and significant feeding
difficulties (9/12) when young.
It was so bad that if I ate a piece of broccoli my blood sugar would plummet into the 40s within 1.5 hours and I'd shake, have
difficulty with
speech and get
severe anxiety.
I would like to think that my students are just a bunch of gifted, enthusiastic readers, but the truth is that all of them are LD learners with
severe dyslexia, disorder of written expression, and various forms of
speech and language
difficulties.
Students with
severe to profound general learning disabilities exhibit a wide and diverse range of characteristics, including a dependence on others to satisfy basic needs such as feeding and toileting,
difficulties in mobility, problems with generalising skills from one situation to another, significant delays in reaching developmental milestones and significant
speech and / or communication
difficulties.