«These findings are independent of traditional risk factors for diabetes and still show a strong connection between the increasing
severity of psoriasis and the increasing risk of developing diabetes, which makes a strong argument for a causal relationship between the two,» Gelfand said.
«It's well established that psoriasis is associated with an increased risk for other comorbidities like chronic kidney disease, diabetes, and cardiovascular disease, but we don't yet understand how
the severity of psoriasis impacts future risk of major health problems,» said the study's senior author Joel M. Gelfand, MD MSCE, a professor of Dermatology and Epidemiology at Penn..
Doctors usually gauge
the severity of psoriasis based on the percentage of your body that is affected.
PMID: 8977698; Cigarette smoking in men may be a risk factor for increased
severity of psoriasis of the extremities.
Understanding about how and why your lifestyle influences
the severity of your psoriasis is information you need to know if you want to recover.
Not exact matches
In order to measure
psoriasis severity, Gelfand and his team used body surface area (BSA), which measures the percentage
of the body covered by
psoriasis.
«The type
of inflammation seen in
psoriasis is known to promote insulin resistance, and
psoriasis and diabetes share similar genetic mutations suggesting a biological basis for the connection between the two conditions we found in our study,» said the study's senior author Joel M. Gelfand, MD MSCE, a professor
of Dermatology and Epidemiology at Penn. «We know
psoriasis is linked to higher rates
of diabetes, but this is the first study to specifically examine how the
severity of the disease affects a patient's risk.»
Around half
of these patients showed improvement as early as week four
of the trial and up to 71 % had shown a high level
of improvement, as measured using a scale called the
Psoriasis Area and
Severity Index, by week 12.
«
Psoriasis severity linked to increased risk of type 2 diabetes: Measuring body surface area in psoriasis can identify highest risk cases, researchers sa
Psoriasis severity linked to increased risk
of type 2 diabetes: Measuring body surface area in
psoriasis can identify highest risk cases, researchers sa
psoriasis can identify highest risk cases, researchers say.»
Psoriasis comes in various levels
of severity from single inflamed and scaly spots, so - called plaques, at the elbows or knees to a very severe disease pattern affecting the entire skin.
Typically,
psoriasis patients experience recurrent flares
of varying
severity during their life.
The study, which published today in the Journal
of Investigative Dermatology, is the first to link
psoriasis severity to an increased risk
of death using an objective measure
of disease
severity — called Body Surface Area (BSA)-- rather than treatment patterns, such as whether or not a patient was receiving oral, injectable or phototherapy treatment for the condition.
When a person has had
psoriasis for a very long time, and I've seen some suffer for 20, 30 years or even longer, then this person may begin to develop anxiety and / or depression which becomes an additional stress adding to the
severity and duration
of their
psoriasis and adrenal fatigue.
The five
psoriasis cases, ranging from mild to severe at the study onset, improved on all measured outcomes over a six - month period when measured by the Psoriasis Area and Severity Index, the Psoriasis Severity Scale, and the lactulose / mannitol test of intestinal perm
psoriasis cases, ranging from mild to severe at the study onset, improved on all measured outcomes over a six - month period when measured by the
Psoriasis Area and Severity Index, the Psoriasis Severity Scale, and the lactulose / mannitol test of intestinal perm
Psoriasis Area and
Severity Index, the
Psoriasis Severity Scale, and the lactulose / mannitol test of intestinal perm
Psoriasis Severity Scale, and the lactulose / mannitol test
of intestinal permeability.