Prior results from Snell and his collaborators, as well as other research groups, indicated that HAP2 is necessary for
sex cell fusion in the organisms that possess the protein.
Not exact matches
«New link found between
sex and viruses: A protein required for sperm - egg
fusion is identical to a protein viruses use to invade host
cells.»
If HAP2 functioned like a viral
fusion protein, Snell reasoned, then disrupting HAP2's
fusion loop should block its ability to fuse
sex cells.
The
sex cells were able to stick together — a process that depends on other proteins — but they were not able to complete the final
fusion of their
cell membranes.
«Developing a vaccine that blocks the
fusion of Plasmodium
sex cells would be a huge step forward,» Snell said, noting that Plasmodium has a complex life cycle that depends on both mosquito and human hosts.
«Sexual reproduction does not require males and females, all it requires is the
fusion of
sex cells from two different mating types.»