Sentences with phrase «shift over time for»

The rulings handed down can shift over time for a variety of reasons.

Not exact matches

«Console developers may shift to cloud - based subscription services that provide greater flexibility and limited upfront costs for gamers while also providing access to regular performance upgrades over time,» he added.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

In an effort to align manager's interests with shareholders, CEO compensation has shifted over time from cash salary and bonus to a mix with stock and options with vesting schedules where stock and options are now 55.6 % of the compensation1, with Earnings per Share (EPS) as one of the targets for vesting stock or options.

It is necessary to remember that such a paradigm shift does not occur overnight - paradigm shifts generally occur over a long period of time, with pockets of thought frequently unaffected by the new for a long period, and often with movement taking place back and forth between paradigms until the new paradigm becomes «settled» and existing social systems are reintegrated.

Where some players might get big - headed from such attention, Doms shifts focus to her team's accomplishments over her own, and always takes time for questions from the media and fans.

players like Ozil always present the fans with a bit of a conundrum, especially when times are tough... if you look around the sporting world every once in awhile there emerges a player with incredible skill, like Ozil, Matt Sundin or even Jay Cutler, who have a different way about themselves... their movement seemed almost too lackadaisical, so much so that it seemed to suggest indifference or even disinterest on the part of the player... their posture always appears somewhat mopey and they generally have an unflattering «sour puss» expression on their face... for some their above average skills are enough to keep them squarely in the mix, as their respective teams try desperately to find a way to get the best out of them visa vie player acquisitions or the reworking of tactics... when things go according to planned the fans usually find a way to accept their unique disposition, whereas when things go awry they become easy targets for fans and pundits alike... in the case of Ozil and Sundin, their successes on the international stage and / or with their former teams led many to conclude that if we surrounded such talented individuals with players that have those skills that would most likely bring the best of these players success would surely follow... unfortunately both the Maple Leafs and our club chose to adopt half - measures, as each were being run by corporations who valued profitability over providing the best possible product on the field... for them, they cared more about shirt sales and season tickets than doing whatever was necessary... this isn't, by any stretch, an attempt to absolve Ozil of any responsibility for his failures on the pitch... there is no doubt oftentimes his efforts were underwhelming, to say the least, but this club has been inept when it comes to providing this prolific passer with the kind of players necessary for him to flourish... with our poor man's version of Benzema up front, the headless chickens in Walcott, the younger Ox and Welbeck occupying wide positions far too often and the fact that Carzola, who provided Ozil with great service and more freedom to roam, was never truly replaced, the only real skilled outlet on the pitch was Sanchez... remember to be considered a world - class set - up man goals need to be scored and for much of his time here he has been surrounded by some incredibly inept finishers... in the end, I'm not sure how long he will be in North London, recent sentiments and his present contract situation seem to suggest that he will depart at season's end, but how tragic would it be if once again we didn't put our best foot forward and failed to make those moves that could have brought championship football back to our once beloved club... so when you think about this uniquely skilled player don't be so quick to shift all the blame on his shoulders because he will not be the first or the last highly skilled player to find disappointment at the Emirates if we don't rid the club of those individuals that are truly to blame for our current woes

like I've said before, Wenger is simply stating that Sanchez is staying so that he can regain some leverage when it comes time to make a deal and to shift the focus back squarely on Sanchez... this is 101 tactics in PR management... the very fact that he even mentioned RVP's name speaks to the utterance arrogance of a man that believes he answers to no one... before you harshly judge Sanchez think carefully about what the ultimate intentions of both parties involved... Sanchez wants to win trophies and get paid generously for his efforts, whereas the club wants to pull the wool over our eyes once again so that we blame the player for wanting the very things we told him we wanted when we brought him in... how many times do we have to go down this road before we realize the only common factor in each of these scenarios is the club itself... trust me, if we showed any ambition Sanchez's contract demands would be much different... just like in other major sports players will take a «home town» discount if they see those in charge making a truly honest attempt to fight for the highest honours in their respective fields... that being said, if they see a team trying to make disparaging remarks about them in the press and not following through on their promises, they will likely try to make them pay a premium for their services or seek greener pastures... btw if anyone simply looks at the score versus Bayern today and thinks that even for a second that this was a deserved victory, just watch the game and judge for yourself... actually save yourself the anguish and just know that if it weren't for Cech and Martinez this could have been a repeat of our Champions League flopping or worse

Wenger himself admitted that he had been pondering over shifting to a back - three for quite some time now and it looks like the signing of Kolasinac has been made with the new system in mind, considering that the Bosnian is a quick and powerful full - back who can also play as a centre - half and as a holding midfielder.

Besides the 2013 University of Washington study, a number of other recent studies have found education ineffective in improving self - reporting by athletes, adding to a growing body of evidence challenging the conventional wisdom that inadequate athlete concussion knowledge is the principal barrier to increased reporting, and suggesting that one of the best ways to combat underreporting by athletes of concussion symptoms may be to shift the focus of educational efforts towards helping coaches facilitate concussion reporting, the theory being that athletes will be more likely to report concussion symptoms if they no longer think that they will be punished by the coach for reporting, such as by losing playing time or their starting position, perceived by their teammates as letting them down, or viewed by their coach as «weak,» all of which have been documented in numerous studies over the past decade as reasons athletes are reluctant to report concussion symptoms.

In other words, we have to be able to sprint several times a game for short bursts (think 30 - 45 second shifts) and do it over the course of a long period of time (e.g. a 60 minute game).

I was there for nearly 19 hours before giving birth, and there were multiple shifts turning over during the time I was in labor.

But, for the first week she was home we had her sleeping round the clock (she was slightly premature, so a very sleepy baby) in the pack and play in our living room, with one of us awake and keeping vigil over her at all times, taking shifts!

Sure, these nurses undergo shift changes and days off, but it is common to see the same nurses caring for babies over time.

Time is ripe for a shift in focus on a new subject, which has remained largely undiscussed over the past decade: drug use (as opposed to addiction) among the general population.

English does serve as a kind of de facto lingua franca in a number of international settings, but it is not, from what I have read, taught universally in South America, many African countries, or in parts of Asia, at least not at an early age for effective language acquisition (and I am unaware of any evidence that English is projected to take over in a reasonable period of time on its own; I have read that in Southeast Asia, for example, emphasis may even be shifting to Chinese).

Senator Kirsten Gillibrand shifts on the controversial anti-piracy legislation, saying it's time for Congress to take «a step back and start over» in order to make sure it won't infringe on internet communications, as critics have argued.

We need to make sure that we are in control over the things that affects us.Anytime there is flood and people loose their life, most of the blame goes to sitting presidents.I am not saying that the central government does not have responsibility to ensure that enabling environment is created.They have a great work to do but as citizens what is our quota?When you move around Accra, sometimes i becomes angry within myself because i am in doubt as to whether our sanitation laws exit.People because of the tax they claim they pay waits for zoom lion workers to come and clean the choked gutters before our houses and shops either than that, it will remain like that.Is it modernity or civilization that has turned us to forget our traditional values or duties of ensuring that our environments is clean?Everybody in our Ghanaian setting knows the responsibility of men and women in making sure that our environments are clean not waiting for flood to occur and we start blaming sitting presidents.To the media, though your responsibility is to keep governments on it toes, you equally have a mandate in educating the public of what we are expected to do as citizens in other to ensure that our dear nation is a better ecosystem for all of us to live.The attention of the media should be shifted from making politicians popular to making us aware as citizens of our responsibilities.I sometimes get confused to hear journalists calling opponents to comment on issues concerning the sitting governments and the only thing that comes to my mind is what do the journalist want to hear from the political opponents?Nothing.They will end up criticizing without giving an alternative.The media should rather resort in questioning people directly to where the problems are coming from.Let us build our institutions.When it comes to energy issues.Citifm will call Hon.KT Hammond who was a deputy minister living who he worked under (His boss at that time) and I always become confused because what can we expect from him?nothing.

If he's accused of stealing money every time he worked day shifts simultaneously for the city and state over those three years, the total amount he made from the state would be $ 32,550, according to the records.

The paper shows «a massive shift» in the behavior of the Arctic Ocean over a short time, says Finlo Cottier, a physical oceanographer with the Scottish Association for Marine Science in Oban who was not part of the study team.

According to analysis by Scott Tremaine at the Institute for Advanced Study in Princeton, New Jersey, the pull of the bulge shifts satellites» orbits over time.

There are almost as many methods of training as there are trainers, but over time the basic strategy has shifted away from punishment or avoidance training (negative reinforcement) to positive reinforcement, where the dog is rewarded for doing the correct thing during most phases of training rather than being punished for not doing what the trainer wants.

To build a stronger case for dogs as hunting companions, she says she'd want to see something like a change in dog breeds over time, with a shift toward characteristics that would make them larger and swifter — and thus better hunters.

Seasonal Shift Of course, looking for trends in tornado data is fraught with potential pitfalls owing to changes in how tornadoes have been reported over time.

First author of the study, William Symes, a graduate student from the Department of Biological Sciences at the NUS Faculty of Science said, «Protected areas are not static but instead dynamic, shifting institutions that change over time, and it is crucial for conservation planners to recognise this.

Although these small time shifts are important for scientists to consider over geologic timescales, eclipse predictions are still pretty good in the short term.

Since the standard for what counts as exceptional has shifted over time, he could conduct an empirical study on how different legal rules affect litigation behavior.

While Sabeti's team had struggled to keep their samples from degrading at the height of the outbreak, during which travel restrictions and shifting priorities left the samples sitting in wait for weeks or months at a time, CDC had a collection and processing method that had been honed by their Viral Special Pathogens Branch over many years responding to Ebola outbreaks in Africa.

«If we shift our sleep and wake times later — for example, sleeping 10 p.m. to 6 a.m., during the week and 1 a.m. to 9 a.m. during the weekends — we push our internal clock later, then come Monday morning it's like we've flown from California to New York over the weekend — we have social jet lag.»

Over time her headaches disappeared and so she decided to reverse engineer what had worked for her and made the shift from a career as an engineer in the pharmaceutical industry to helping other migraineurs solve their migraine issues using a functional medicine approach.

For the longest time, women wore dresses that would enhance their looks, irrespective of them being comfortable or not, but in the 1920, s «flapper» style shift dresses were introduced and for the first time in history, women wore clothes that focused on women's comfort over their looks; they were loose, relatively more revealing, and had an androgynous cFor the longest time, women wore dresses that would enhance their looks, irrespective of them being comfortable or not, but in the 1920, s «flapper» style shift dresses were introduced and for the first time in history, women wore clothes that focused on women's comfort over their looks; they were loose, relatively more revealing, and had an androgynous cfor the first time in history, women wore clothes that focused on women's comfort over their looks; they were loose, relatively more revealing, and had an androgynous cut.

I wore it to work probably for over half my shifts, and a lot of times with skirts (seen here).

There is a shift in the way things happen when you are over 40 years old, and unfortunately, the over 40 singles make some serious dating mistakes and end up remaining single for a very long time.

As with «The Crucible,» Day - Lewis» big explosion — this time into outright stark - raving, animalistic rage, drooling and towering over Eli while pushing at him to tease him — wouldn't count for much if not for the slow - burn of the rest of the performance, with the actor's gradual shift from at least somewhat human to All - Powerful American Businessman as a Monster shown by his body going from upright to crooked, his face from quietly hateful to anything but.

Race is a political grouping created to support slavery and colonialism, and its boundary lines have shifted over time and across nations to suit political ends... For the last three centuries, science... has been instrumental in justifying the concept of biological races — and this century's genomic science is no different... Despite the scientific and political evidence, some scientists are attempting to modernize the myth that race is a biological category... What's new is that today's racial science claims to divide human beings into natural groups with more accurate precision and without the taint of racism.»

Personally speaking, the changes implemented in RE7 were something the franchises was in desperate need of for quite some time and I think it is a testament to just how good Capcom's latest entry in the survival horror genre is that despite initial skepticism by long - time fans over something as controversial as the shift to first person many people have walked away absolutely loving the game.

A few of those tonal shifts don't work, but for the most part, any time things go over the edge, they're dragged right back, then pushed back again.

It is time for the evaluation debate over school choice to begin shifting its focus to real world outcomes, like high school graduation and college attendance rates.

NAEP, known for offering a dependable measure of national student progress over time, has always had to strike a balance between remaining independent of passing fashions in curriculum and instruction while also appropriately reflecting important shifts in the educational landscape, according to the report.

Many systems, however, still appear to be grappling with the deep cultural shifts — both in their schools and communities — required to let go of time - based practices that have dominated education for over a century.

For example, the department can require each state to submit an annual report detailing the racial, ethnic, and economic makeup of each of its schools and districts, and how these demographics have shifted over time.

«If you shift the perspective from what is best for adults to what is best for students, then it's super clear that value - added can improve the system over time,» he said.

A potential factor behind the shift in KS3 curriculum time towards EBacc subjects is that some schools have shifted from a traditional three - year KS3 to a shortened two - year version, enabling study for GCSE courses to run over three years.

Over time, the focus of summer school has shifted from providing opportunities for struggling...

Over the coming years, as we provide teachers and schools with data on how teaching practices are tied to students» performance, we plan to investigate the degree to which classroom - and school - level teaching practices shift over time toward practices which have been identified as more effective for enhancing student achievemOver the coming years, as we provide teachers and schools with data on how teaching practices are tied to students» performance, we plan to investigate the degree to which classroom - and school - level teaching practices shift over time toward practices which have been identified as more effective for enhancing student achievemover time toward practices which have been identified as more effective for enhancing student achievement.

Over time, the focus shifted toward classroom practice, with detailed school assessments, support for curriculum development, and training to establish Professional Learning Communities.

The Office of Head Start (OHS) Administration for Children and Families Offers an in - depth description of the shifts in parent engagement that have occurred over time.

Webinar Recording: Key Teaching and Learning Shifts for Personalized Learning: Preparing for Success This webinar focused on the key teaching and learning shifts that occur in successful personalized learning settings over time, including how these shifts can help improve students» college and career readShifts for Personalized Learning: Preparing for Success This webinar focused on the key teaching and learning shifts that occur in successful personalized learning settings over time, including how these shifts can help improve students» college and career readshifts that occur in successful personalized learning settings over time, including how these shifts can help improve students» college and career readshifts can help improve students» college and career readiness.

Nonetheless, I would have a really hard time forking over $ 44,350 for a base stick - shift SRT8.

of torque (10 percent increase), with better fuel economy and increased refinement 6,000 - mile maintenance schedule for all gasoline engines Improved steering linkage for 4x4 models Trailer Sway Control added to available Electronic Stability Program (ESP) Tire Pressure Monitoring (TPM) system available 2007 MODEL YEAR YES ® Essentials Stain resistant, odor resistant, anti-static seat fabric incorporated into vehicles with cloth seats Power accessory delay E85 compatible 4.7 - liter V - 8 engine (Flexible Fuel Vehicle — FFV) Optional Electronic Stability Program (ESP) Optional remote start One - touch, three - blink lane change feature 2006 MODEL YEAR Multi-displacement System (MDS) on 5.7 - liter engine is a fully functioning cylinder deactivation system on a pickup truck (first for segment) and enables fuel economy improvements of up to 20 percent Variable Line Pressure (VLP) feature on four - speed automatic transmission (mated with 3.7 - liter V - 6 engine) results in improved fuel economy and smoother shifts Front - axle disconnect system (standard on 4x4 models) minimizes energy consumption and improves fuel economy NV244 full - time electric transfer case standard on all 4x4 models delivers 45/55 front / rear torque split when four - wheel drive is activated Optional all - wheel - drive electronic transfer case «Tow / haul» feature provides crisper shifts and reduces gear searching when towing Re-engineered hydroformed, fully boxed frame with increased torsional rigidity and bending stiffness for enhanced ride and handling capability and reduced transfer of noise Reduced drag brake calipers contributing to enhanced aerodynamics Coil - over shock, double wishbone front suspension on 4x4 models Specifically tuned monotube shock absorbers Re-tuned springs, jounce bumpers and suspension bushings for enhanced driving dynamics Re-engineered body mount design results in quieter cabin experience and more comfortable ride Re-engineered engine and transmission mounts for enhanced ride and handling characteristics