Initially the dose is minimized by the spacecraft's polar orbit, which ducks under the radiation belt, but the orbit
shifts over time due to the torquing from Jupiter's gravitational field.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates
due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated
shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products
over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program
due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from
time to
time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Due to the immense confusion, my reality and my understandings of basic concepts
shifted and changed
over a short period of
time, so I wrote out of desperation, in search of anything that would keep me «steady,» that would keep me anchored to anything solid, to anything of real substance.
http://illconsidered.blogspot.com/2006/04/historically-co2-never-causes.html 100 years of
shift does not factor into the larger scale phenomena http://illconsidered.blogspot.com/2006/01/one-hundred-years-is-not-enough.html Until climatologists can properly make models that reflect the entire global history and take into account plate position and how high the plates ride, oceanic levels
due to this and the position of oceans, overall insolation, overall daylength and its effects on average global temperature and factor in known carbon dioxide levels
over that
time period, then they will be unable to give any correlation between current carbon dioxide levels and global temperature.