Not exact matches
These
short sequences — usually about 500
nucleotides in length — are termed expressed
sequence tags.
The blade, he found, is an enzyme that always cuts the viral DNA code where it finds a particular
short sequence of
nucleotides.
Another breakthrough came a few years later with the discovery of «microsatellites»,
short sequences of two to four
nucleotides.
Short read sequencing has allowed exact identification and calling of single nucleotide polymorphisms and short indels and has substantially advanced the study of human populat
Short read
sequencing has allowed exact identification and calling of single
nucleotide polymorphisms and
short indels and has substantially advanced the study of human populat
short indels and has substantially advanced the study of human populations.
Next - gen
sequencing is particularly useful for analyzing highly fragmented DNA, adds Eske Willerslev, a geneticist at the University of Copenhagen's Natural History Museum of Denmark, because it can capture the
sequences of exceedingly
short stretches of
nucleotides.
Their work arose out of a discovery in the late 1980s of neighboring bacterial DNA segments consisting of repeating
nucleotide sequences, which flank
short segments.
MNLPs join the list of
sequence variations that have been discovered in recent years, including SNPs (single
nucleotide polymorphisms), INDELs (insertions or deletions of various lengths), and STRs (
short tandem repeats).
This is a highly parallel
sequencing approach that involves synthesizing
short regions of identical DNA fragments on magnetic beads, packing millions of them into a chamber and then extending each of those molecules while detecting the addition of fluorescently labeled DNA building blocks or
nucleotides.
Both the modification and the restriction enzymes become activated on a
short specific
nucleotide sequence, the recognition
sequence, which is the substrate for methylation.