We do this because reducing variability means that we will have greater power in our statistics to
show phenotypic differences and ultimately be able to use fewer animals.
Because people exposed to Ebola
show phenotypic variability in susceptibility to infection and disease severity, it is likely that human genetic variation contributes to individual immunity and infectivity and that host genetic differences are one factor among many that interact to influence the infection.
In these analyses, six of 90 F1 progeny (∼ 7 %) showed a distinct phenotype compared to the haploid parental strain XL280 and the remaining 84 progeny
showed no phenotypic differences from the wild - type (Figure 3A and Figure S3).
Not exact matches
A recent study made by scientist in India
showed that the derived lines of Golden Rice produced
phenotypic abnormality and poor agronomic performance making it unfit for commercial cultivation.
In recent study, scientists from India
showed that the derived lines of Golden Rice produced
phenotypic abnormality and poor yield performance making it unfit for commercial cultivation.
«This
shows the power of our research model to quickly gather large amounts of
phenotypic and genotypic data for scientific discovery.»
Phenotypic analyses
showed that the anti-Plasmodium mechanism requires small populations of replicating bacteria and is mediated through a mosquito - independent interaction with the malaria parasite.
The researchers also analyzed genes with known
phenotypic association and
show that some of the hunter - gatherers likely had blue eyes and darker skin, whereas the early farmers had lighter skin and brownish eyes.
The cells
showed good viability and demonstrated spreading and other
phenotypic behavior consistent with cells interacting with collagen hydrogel scaffolds.
The results
show the plants have great
phenotypic plasticity and do not all change in the same ways.
Although protein is highly conserved in evolution, previous mtEF4 gene knockouts in some model organisms did not
show significant
phenotypic change.
Our findings
show the significance for structural variations on
phenotypic diversity and a novel role for HOXB8 in feather formation.
Our findings
show that sex can generate
phenotypic and genotypic diversity de novo in the pathogenic yeast C. neoformans with implications for other eukaryotic microbes and pathogens, including other fungi and parasites that are common pathogens of humans.
With this unique resource in hand, we have already characterized several candidate structural variation which
show evidence for
phenotypic adaptation, which can function to drive species evolution,» said Emerson.
The identification of large - size individuals among the australopithecines — i.e. hominins commonly presumed to be small - bodied on average —
shows also that the available fossil record can be misleading, resulting in an underestimate of the hominin
phenotypic diversity in any given period.
However, new evidence
shows that these environmental -
phenotypic interactions are in a growing number of organisms.
An alternative approach, most common for anti-infectives, is to use compounds («
phenotypic inhibitors») which have already been
shown to be active against the target organism in the living pathogenic cell as chemical leads for improvement by Medicinal Chemistry, towards systemically active Candidate Drugs.
We also
show that analysis of minor populations increases power to detect
phenotypic resistance in second - line drugs without appreciable loss of specificity.
Through systematic annotation of the resulting movies, we developed a
phenotypic profiling system, which
shows high correlation with cellular processes and biochemical pathways, thus enabling us to predict new functions for previously uncharacterized genes.
Inducible genetic labeling
showed that transgene - expressing HSCs gave rise to other
phenotypic HSCs, confirming their top position in the differentiation hierarchy.
Single
phenotypic traits measured and extracted in the cortex at day 6 postgermination could be all fitted by the three models as well, similarly as
showed for the epidermis (Fig 3A, n = 40, Tables EV3 and EV4).
Phenotypic characterizations reveal high levels of CD44, α2β1 integrin, and β - catenin expression in holoclones, whereas meroclones and paraclones
show markedly reduced expression of these stem cell markers.
It
shows a clear relationship between
phenotypic (physical) measures and later signs of osteoarthritis.
Phenotypic traits that are common across many breeds, such as brachycephaly, are likely to be identical by descent, just as many other specific genetic traits have been
shown to be shared between different dog breeds [13], [14], [15], [16], [17], [18], [19], [20], [21], [22].
Moreover, for the first time, they
show that changes in whole - organism
phenotypic responses are accompanied by changes in the expression of genes related to intracellular regulatory processes rather than genes thought to be essential for calcification.
Similar transgenerational
phenotypic resilience to increased temperature has also been
shown for sea urchins [107,108].
Biometric analyses
showed that these multi-source measures of childhood impulsivity and inattention were highly heritable, with genetic variance accounting for 70 - 80 % of the
phenotypic variance in many of the models.