Sentences with phrase «show telomerase»

F: Demonstrates that extensive serial dilutions of central - intermediate and peripheral area HCECs only show telomerase activity in the endothelial peripheral area as taken from mixed aged donors (21 - 52 years).

Lanes 3 and 5 show telomerase activity in the peripheral regions of the HCEC from the 16 - and 66 - year - old donors, respectively.

Not exact matches

Pioneers like Dr Dean Ornish and Dr Caldwell Esselstyn where among the first to show that if you combined a low fat, plant based diet, with walking and stress management, not only could you prevent and reverse heart disease (and many other chronic conditions), but you could also increase telomerase activity.

By measuring telomerase activity, investigators determined that the group that smoked without drinking red wine showed a 56 % decrease in telomerase activity while the drinking group showed only a 20 % decrease.

This model structure of the catalytic portion of telomerase shows how the TFLY motif (green) is positioned at the entry of the pocket that guides the RNA template in the interior cavity of the telomerase ring and were the active site of the enzyme if located for catalysis.

Within this portion they identified the TFLY, a conserved element that they showed is involved in binding the RNA component of telomerase and this interaction is important for telomerase protein - RNA assembly and activity.

«But mouse studies show that when you suppress telomerase, cells can upregulate ALT.

The variant lies near a gene called telomerase RNA component, or TERC, and earlier studies in animals have shown that low TERC expression is associated with shorter telomeres, and faster biological aging.

Studies have shown the modification of TERC (TElomerase RNA Component) expression may be therapeutically beneficial in DC patients.

Now two reports show that, with the help of an enzyme called telomerase, human cells can divide forever in the laboratory without turning cancerous.

Some studies in mice have shown that elevated telomerase activity leaves the animals more susceptible to skin tumors and breast cancer, so maybe there is no free lunch.

Figure 2B also shows positive telomerase activity in the peripheral region of a 55 - year - old donor (lane 2) and negative activity in the central intermediate region (lane 1).

The figure shows that there was no telomerase activity detected for both central intermediate and peripheral regions of 26 - and 55 - year - old donors (lanes 2, 3, 4, and 5, respectively).

Those assays were negative for telomerase activity (data not shown).

Lundblad has shown that telomerase is switched on just as a cell has finished copying its genetic material, and then rapidly switched off, through assembly and disassembly of its protein subunits.

Telomerase: Increased levels of telomerase have been shown to extend life in mice, as well as reducing cancer incidence in thaTelomerase: Increased levels of telomerase have been shown to extend life in mice, as well as reducing cancer incidence in thatelomerase have been shown to extend life in mice, as well as reducing cancer incidence in that species.

Various types of meditation have been shown to improve well - being among different populations such as physicians and the general public.14, 15, 16 Preliminary evidence suggests that meditation - based interventions may slow cellular aging rates by increasing telomerase activity, but many such studies lacked an active control group.17, 18 Recent randomized trials in breast cancer suggest that long - term intensive meditation interventions might have positive effects on telomerase activity.

Theoretically, a sustained increase could stabilize or even lengthen telomeres over time, as shown in a previous study where intensive lifestyle intervention led to higher telomerase activity after 4 months, and longer telomeres after 5 years, with such changes associated with better adherence.43, 44

Regular meditators had lower telomerase at baseline, but also showed a significant increase in peripheral blood mononuclear cell telomerase activity post treatment that was not observed in the other two groups.

Researchers at the Spanish National Cancer Research Centre (CNIO) published proof - of - principle results showing a role for telomerase reverse transcriptase (TERT)...

Regular meditators showed a trend toward increased telomerase activity compared with randomized women, who showed increased plasma Aβ42 / Aβ40 ratios and tumor necrosis factor alpha (TNF - α) levels.

E: Shows the existence of telomerase activity following dilution of a peripheral HCEC.

A study by Dr. Dean Ornish and his team showed that lifestyle changes including diet, exercise, and stress management techniques made a difference in telomerase levels.

Of the two telomerase components analyzed, Tert (telomerase reverse transcriptase) expression did not show any differences between groups, but Terc (telomerase RNA component) transcription was significantly higher in the IVC testes (Fig. 2B).

Researchers at the University of California were the first to show that meditators have significantly higher telomerase activity than non-meditators.

There have, however, been some studies with encouraging results; for example, Chinese scientists took human endothelial progenitor cells exposed to resveratrol, and showed that telomerase activity increased.