One of the participants of the experimental program was a 66 - year old man whose MRI
showed hippocampal volume at only the 17th percentile for his age.
Not exact matches
«There are no other treatments
shown to preserve
hippocampal volume in those that may develop Alzheimer's disease.
However, after 10 months on the protocol a follow - up MRI
showed a dramatic increase of his
hippocampal volume to the 75th percent!
Stress paradigms in rodent models have been associated with elevated anxiety and contrasting alterations in neuronal morphology in the hippocampus and amygdala, with dendritic atrophy observed in the hippocampus and increased dendritic arborization in the amygdala.12, 13 Developing rodents deprived of maternal nurturance
show decreased
hippocampal volume and altered stress reactivity.14 An epigenetic mechanism for this effect has been elaborated.15 Importantly, controlled trials that have randomized institutionalized toddlers to early therapeutic foster care vs institutionalization have documented the deleterious effects of early relative deprivation on cognitive outcomes.16
Research
shows it has the potential to promote normal developmental trajectories for high - risk children, such as those from low - income backgrounds and / or those with very premature births.13 In contrast, unresponsive parenting may jeopardize children's development, particularly those at higher risk for developmental problems.14 The critical importance of responsive parenting is highlighted by recent evidence identifying links between high levels of early responsive parenting and larger
hippocampal volumes for normally developing preschool aged children.