Sentences with phrase «showed hyperactivation»

In addition, many cancer cells express insulin receptors (IRs) and show hyperactivation of the IGF1R - IR pathway.

Not exact matches

By studying human cancer cells and animal models of cancer in the lab, our researchers have shown that loss of PTEN leads to high levels of PI (3,4) P2, which could result in hyperactivation of AKT.
In line with our in vitro data, Pkn1 — / — mice showed AKT hyperactivation, elevated NeuroD2 levels, and reduced expression of PF - PC synaptic markers during stages of PF maturation in vivo.
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