Sentences with phrase «showed synergistic effects»

When compared to donepezil in memory assays, J147 performed equally well or superior, and even showed synergistic effects in the fear conditioning assay.

Holy basil leaf extract also showed a synergistic effect with silymarin, the active ingredient in milk thistle, an herb used to promote liver health, in the study.

Not exact matches

In tests on EGFR - dependent lung cancer cell lines, Tan and colleagues show that the drugs gefitinib and bosutinib «showed additive and synergistic effects.»

However, he says, studies like this can «give us some clue» about what can result from multiple insults to the developing brain because it shows experimentally that prenatal and postnatal impacts can work together to have synergistic effects on later behavior, he says.

This study shows how microplate respirometry can be successfully used to assess changes in respiration of coral larvae, and our findings suggest that the effects of thermal stress and nitrate enrichment in coral larvae may be species specific and are neither additive nor synergistic for O. faveolata or P. astreoides.

This is in accordance with previous reports that decitabine and 5 - azacytidine produce a marked synergistic effect in combination with suberoylanilide hydroxamic acid and romidepsin in T - lymphoma cell lines by modulating cell cycle arrest and apoptosis.26, 27 As a mechanism of action, KMT2D mutations of B - lymphoma cells promote malignant outgrowth by perturbing methylation of H3K4 that affect the JAK - STAT, Toll - like receptor, or B - cell receptor pathway.28, 29 Here our study indicated that dual treatment with chidamide and decitabine enhanced the interaction of KMT2D with the transcription factor PU.1, thereby inactivating the H3K4me - associated signaling pathway MAPK, which is constitutively activated in T - cell lymphoma.13, 30,31 The transcription factor PU.1 is involved in the development of all hematopoietic lineages32 and regulates lymphoid cell growth and transformation.33 Aberrant PU.1 expression promotes acute myeloid leukemia and is related to the pathogenesis of multiple myeloma via the MAPK pathway.34, 35 On the other hand, PU.1 is also shown to interact with chromatin remodeler and DNA methyltransferease to control hematopoiesis and suppress leukemia.36 Our data thus suggested that the combined action of chidamide and decitabine may interfere with the differentiation and / or viability of PTCL - NOS through a PU.1 - dependent gene expression program.

But when it comes to blood sugar and insulin sensitivity, the positive effects of fish oil are so powerful that they almost rival the effects of exercise, while a large new study showed that the synergistic blood sugar - lowering effect of fish oil and regular exercise is more than impressive.

Research shows that taking them together creates a synergistic effect, making them potent tools for quenching the inflammation and damage in the small intestines and elsewhere in the body, including the thyroid.

Although each is a powerful anti-inflammatory alone, research shows that taking resveratrol and curcumin together creates a synergistic effect, making them potent tools for quenching the inflammation and damage associated with autoimmune flare - ups and chronic inflammation.

A combination of oils from clove and cinnamon were shown to have a synergistic effect on inhibiting the growth of E. coli in study (8).

But one clinical study involving 24 healthy female subjects showed «synergistic» effects on cognition and mood, which incidentally translated into improved blood pressure.

Studies show that caffeine and L - theanine can have synergistic effects.

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Apple has shown itself a master of creating synergistic effects between its products, with the Apple Watch, AirPods, Mac, and now HomePod each feeding the demand for an iPhone user to remain an iPhone user.