But the next big trial is likely to focus on people with relatively early HD symptoms, so that it has the best chance of
showing slowed progression.
Speedo showing 56k miles which is backed up by many old MOT certificates
showing the slow progression of the mileage.
Not exact matches
Likewise, despite decades of tries, there's still no cure for Parkinson's disease or even a drug that's been
shown to
slow its neurodegenerative
progression.
Behind him in the pecking order, Martin Kelly has
shown excellent promise as a backup — even being linked with a first England call up — and to sign a 29 year - old would surely
slow his
progression.
The Welshman has
shown on a number of occasions that he has the ability to play at the highest level, but numerous injuries have stunted and
slowed his
progression over the years, and there are always worries that we could lose him to injury at any point in the season.
You'll hear and read many impressive things in the coming days, weeks, months and perhaps even years about the tie, but what it
showed me was that Liverpool's natural
progression under Jurgen Klopp is under no signs of
slowing down.
A few drugs have
shown promise in cell culture or animal models, but clinical trials in humans are time consuming because of the
slow onset and
progression of the disorder's clinical symptoms.
«Huntington disease prevention trial
shows creatine safe,
slows progression.»
«Previous pilot studies researching the use of DBS in Alzheimer's have indicated the potential to
slow cognitive decline in some patients, and have even
shown metabolic changes in the brain that may
slow the
progression of the disease.»
Just one FDA - approved drug, riluzole, has been
shown to
slow the disease's
progression — and only minimally.
The team also
showed that there are three distinct phases of MAO activity that change along with Alzheimer's
progression: a
slow initiation stage, a subsequent aggressive stage and finally a saturation stage.
«Drug trial
shows promise for deadly neurological disorder: Cyclodextrin
slows progression of Niemann - Pick type C.» ScienceDaily.
In the drug trial, researchers have
shown that treatment with a type of sugar molecule called cyclodextrin
slows progression of the disease.
In addition to demonstrating that disease
progression slowed with cyclodextrin, Ory and his colleagues assessed biomarker measurements in the blood that
showed evidence that the drug was removing cholesterol from the brain.
A different drug called miglustat also
shows evidence of
slowing NPC
progression.
«If we can identify infants with NPC early, we could direct these children to clinical trials, potentially beginning treatment before they have begun to
show symptoms of neurological damage, hopefully
slowing disease
progression and improving quality of life.»
A new study
shows that restoring the lipids that help keep lung tissue flexible and inflated can help
slow disease
progression in laboratory models of pulmonary fibrosis.
Treatment with miglustat, an inhibitor of lipid synthesis that is approved outside the U.S. for treatment of NPC, has
shown evidence of
slowing disease
progression.
New research into Amyotrophic Lateral Sclerosis (ALS)-- also known as motor neuron disease —
shows that specific immune cells may help
slow progression of the disease, an important step towards developing new therapies to treat patients.
Next steps will be to conduct efficacy studies to
show whether reducing mutant huntingtin can
slow down disease
progression.
Dr. Ready said the crossover at
progression could have influenced the survival data; in fact, an analysis of six patients who crossed over to sunitinib
showed that tumors that had been growing either
slowed their growth or shrank following crossover.
The study conducted in the laboratory of Don Cleveland, Ph.D., UCSD Professor of Medicine, Neurosciences and Cellular and Molecular Medicine and member of the Ludwig Institute for Cancer Research,
shows that therapeutic molecules known as antisense oligonucleotides can be delivered to the brain and spinal cord through the cerebrospinal fluid (CSF) at doses
shown to
slow the
progression of ALS in rats.
Behaviorally, the mice with 110 CAG repeats
showed a sharp decline in both rotarod and open field performance from around 4 weeks of age whereas the 240 CAG repeat mice displayed a 2 - 3 week delay in the onset of behavioral decline with a much
slower progression of decline in both tasks as compared to 110 CAG repeat counterparts.
Finally, it's worth pointing out that it's possible the trial will
show that the drug doesn't work - that it doesn't
slow the
progression of HD.
A new discovery
shows that an interaction in neurons could
slow the
progression of Parkinson's disease.
These knockouts
showed a significantly
slower disease
progression and longer survival.
Data
show that infected children with
slow progression of disease and Elite controllers develop neutralizing antibody and ADCC.
And in animal studies using mice with HD, research has
shown that «environmental enrichment» - giving the mice more stimulating surroundings - delays the onset and
slows the
progression of the disease.
There are currently no disease - modifying treatments that have been
shown to
slow the
progression or delay the onset of HD in humans; however, several compounds have demonstrated promise in animal models of HD.1 Robust and sensitive markers of disease
progression are required to assess their efficacy in humans.
Namely, not only that the lifters in the «
slow speed» group built 3 times more muscle, but they also
showed nearly five times more
progression in strength than the «fast speed» group!
300 patients with Alzheimers, and those with their vascular risk factors treated
showed significantly less decline;
slowed progression of their disease.
The ketogenic diet (KD) is a low carbohydrate, high fat diet which decreases blood glucose and elevates blood ketones and has been
shown to
slow cancer
progression in animals and humans.
All dietary intervention studies in MS so far were either negative in terms of
slowing disease
progression or
showed only a positive trend without major effects.
A daily serving of papaya has also been
shown to reduce the risk of macular degeneration and
slows down the
progression of other age related diseases.
The latest research on neurodegenerative disease
shows that not only can you prevent neurodegenerative diseases such as Alzheimer's and Parkinsons, but you can also
slow their
progression and even reverse them.
Ghee from grass - fed cows contains the cancer - fighting fatty acid conjugated linolenic acid (CLA) which aids in weight loss and has been
shown to
slow the
progression of some types of cancer and heart disease.
Classically, OA has been treated with non-steroidal anti-inflammatory drugs (NSAIDs), although research has
shown that these medications only offer pain relief but do not
slow down the
progression of the disease.
High dose selenium has been
shown to
slow the
progression of ARMD and researchers suggest it may be through reducing VEGF production in the retina (10).
A study
showed just 15 goji berries a day improved and
slowed the
progression of AMD.
Studies have
shown that supplementing with L - carnitine
slows the
progression of fast - developing Alzheimer's disease.
Furthermore, turmeric is a strong neuroprotective that has
shown promise in
slowing the
progression of neurological diseases like Alzheimer's and depression.
Moreover, models of experimental carcinogenesis in animals have
shown the potential to modify a number of metabolic actions and steps in the cell cycle in a way that early events in the cascade of cancer development may be counteracted while stages of
progression may be
slowed down.
That being said, moderate alcohol consumption has been
shown to
slow the
progression of rheumatoid arthritis.
A study conducted by the Institute for Basic Research in Developmental Disabilities in New York
showed that walnuts can improve memory deficits and learning skills and may also have a beneficial effect in reducing the risk, delaying the onset, and
slowing the
progression of Alzheimer's disease.
Research
shows that social interactions for people living with dementia can be more cognitively stimulating than any other exercise, and may contribute to
slowing the
progression of the disease.
Research
shows low phosphorous diets
slow kidney disease
progression.
They have also both been
shown to actually
slow down the
progression of adrenal disease.
However, some studies have
shown that low doses can be used safely over the long - term and may even
slow the
progression of chronic kidney disease in cats.3 Other medications like buprenorphine, tramadol, amantidine, gabapentin, and corticosteroids (e.g., prednisolone) have all been used to improve patient comfort in cats with arthritis.
Some studies have
shown that regular exercise may help to delay atrophy and
slow the
progression of spinal cord damage — a healthy diet is also beneficial as is the maintenance of a healthy bodyweight.
The medication
shows promise in
slowing the
progression of the disease.