Several studies have
shown median survival to be more than 6 months.
In one study dogs treated with surgery for olfactory meningiomas,
showed a median survival of 138 days.
However, in a separate study, 35 % of dogs benefited from piroxicam and mitoxantrone and
showed a median survival time of 291 days.
Fifteen dogs treated in this manner
showed a median survival of 287 days and an overall survival of 956 days.
According to some reports, dogs treated with system chemotherapy
showed a median survival time of 5 months to 31 months.
Not exact matches
Study results
show that patients with prior knowledge of MGUS had better overall
survival (
median 2.8 years) than patients with MM who didn't know when they had MGUS (
median survival 2.1 years), although patients with prior knowledge of their MGUS status had more coexisting illnesses.
Appearing in Lancet Oncology, long term results of EORTC trial 22921 with 10.4 years
median follow - up
show that 5 - FU (fluorouracil) based adjuvant chemotherapy after preoperative (chemo)- radiotherapy for patients with cT3 - resectable T4 M0 rectal cancer does not improve
survival or disease - free
survival.
For example, data from seven multi-institutional U.S. clinical trials
showed patients who had no visual residual disease had a
median survival of 64 months compared with 29 months for those with minimal residual cancer.
The data reported today
show continued increases in
median event - free
survival and muscle function scores as well as achievement of developmental milestones.
As a recent study has
shown, clearing senescent cells both reduces negative effects of aging pathologies and also extends
median lifespan and
survival.
In 2005, the chemotherapy temozolomide (Temodar ®) was approved to treat newly diagnosed GBM patients based on a randomized phase III clinical study that
showed that it added 2.5 months to the
median survival of patients.
The approval came on the heels of the first phase III clinical trial ever
shown to improve overall
survival in patients with the disease, with
median overall
survival of 10.1 months, versus 6.4 months in the control group.
Although researchers found that delivering the Isis drug directly into the brain nearly doubled
survival time in a mouse model of SMA3, systemic administration in the rodents — which usually die within two weeks — has been
shown to extend
median survival by up to eight months.
The results also
showed that the combination therapy significantly prolonged progression - free
survival, with a
median of 19 months for the combination versus 9 months for the chemotherapy group.
Studies have
shown that surgery to remove the spleen (splenectomy), offers a
median survival time of 19 - 83 days.
In the 50 % of cats that
showed at least some response to therapy,
median survival time increased to 150 to 180 days as opposed to 75 to 86 days in the 50 % that did not respond.
Recently, a
median survival time of 7 months was reported for dogs receiving radiation therapy along with chemotherapy; whereas a combination of surgery and chemotherapy
showed more encouraging
median survival rates of 235 - 366 days with up to 28 % surviving two years after diagnosis.
In the 50 % of cats that
showed at least some response to therapy,
median survival time increased to 150 - 180 days as opposed to 75 - 86 days in the 50 % that did not respond.