Not exact matches
However, Stephen Back, a neurologist at the Oregon Health and Science University in Portland, points out that there is not yet proof that myelin - producing
cells are stuck in arrested development in infants with brain
injuries, although this has been
shown both in mice and in adults with multiple sclerosis.
In an earlier article, Jenkins
showed that females with severe hypoxic ischemic
injury benefit from a combination treatment of hypothermia and NAC, which provides the rate - limiting amino acid for the primary anti-oxidant in all
cells.
A new mouse study
shows that triggering a gene inside astrocytes activates the star - shaped
cells and may improve the brain's ability to heal from a range of debilitating conditions, from stroke to concussions and spine
injuries.
Dr. Gabriel Ferguson, a postdoctoral fellow in the lab of Dr. Martinez - Agosto and first author of the study, built upon the lab's previous research that utilized the blood system of the fruit fly species Drosophila,
showing that a specific set of signals must be received by progenitor
cells to activate their differentiation into
cells that can work to fight infection after
injury.
Earlier work has
shown that grafted stem
cells reprogrammed to become neurons can, in fact, form new, functional circuits across an
injury site, with the treated animals experiencing some restored ability to move affected limbs.
«We now have the first marker for the capacity of brain immune
cells to remove toxic materials,» says Haass, «and its increase long before full Alzheimer's dementia
shows that there is early neuronal
injury that does not yet affect memory, but already triggers a microglia response.»
In addressing the first question, the study
showed that the brain's immune
cells, microglia, which are known to become activated by LPS exposure as well as in most brain
injuries and diseases, begin spewing out pro-inflammatory factors that change astrocytes» behavior.
The study
showed that a peripheral nerve
injury in rats sends a message from damaged nerve
cells to spinal cord immune
cells known as glial
cells, which normally act as «housekeepers» to clear out unwanted debris and microorganisms.
The experiment
shows that β1 - integrin — one of 28 types of integrin — maintains a link between the stem
cell and its environment, and interacts biochemically with a growth factor called fibroblast growth factor [FGF] to promote stem
cell growth and restoration after muscle tissue
injury.
While it is generally accepted that MSC are mostly quiescent during postnatal life, MSCs in different niches can presumably differentiate into the specific
cells of closely related niches during physiological turnover,
injury or disease, as
shown for other stem
cell types (e.g., muscle satellite
cells).
Takayama's team was able to confirm that the sounds were associated with
injury to the
cells — suggesting that the model was accurately approximating what happens in a diseased lung — and to
show how a therapeutic surfactant, which lowers the tension between liquids and solids, could reduce those
injuries.
The MRI results - to - date for 94 % (17/18) of the subjects in Cohorts 2, 3, and 4 are consistent with formation of a tissue matrix at the
injury site, which is supportive evidence
showing that AST - OPC1
cells have durably engrafted at the
injury site and helped to prevent cavitation.
In 1963, Hruban and colleagues
showed that damaged structures within a
cell were sequestered and degraded, and that this was a normal and beneficial response to cellular
injuries such as starvation or oxygen deprivation.
Dr. Keristead created oligodendrocytes from hESCs, and
showed that an injection of these
cells into rats with spinal cord
injuries could significantly improve their motor functions.
AST - OPC1, an oligodendrocyte progenitor
cell population derived from human embryonic stem
cells, has been
shown in preclinical testing in animals and in vitro to have three potentially reparative functions that address the complex pathologies observed in demyelination disorders, such as spinal cord
injuries, and multiple neurodegenerative diseases, including multiple sclerosis and white matter stroke.
Images of hMito + (red) and GFAP (green) immuno - reactivity within hGDAsBMP (A, C, E, F) and hGDAsCNTF (B, D, G, H) transplants at the center of
injury sites
showing comparable densities of GFAP + intermediate filaments (green) within hMito immuno - positive
cell bodies and process of both types of hGDAs.
This is the «
show reel» of Dr Haluk Deda, a Turkish neurosurgeon who is setting up shop in Dubai, where he plans to offer autologous stem
cell transplants to treat chronic spinal cord
injuries and ALS, a condition with no known cure that generally leads to death within three to five years of diagnosis.
Calcitonin gene - related peptide (CGRP) has been
shown to improve survival of lung epithelial
cells and reduce hyperoxic lung
injury in rats.
Research has
shown that high temperatures can damage and kill cancer
cells, usually with minimal
injury to normal tissues.
Studies have
shown that excess iodine causes thyroid
injury by generating reactive oxygen species, which lead to premature damage and programmed
cell death in thyroid tissues.
Stem
cells show remarkable potential as treatments for a variety of equine disorders from orthopedic
injuries to organ regeneration, but we still need to answer...
Stem
cells show remarkable potential as treatments for a variety of equine disorders from orthopedic
injuries to organ regeneration, but we still need to answer many questions to unlock the full potential of these biological superheroes.
An international team of researchers, funded by Morris Animal Foundation, has
shown that adipose (fat) stem
cells might be the preferred stem
cell type for use in canine therapeutic applications, including orthopedic diseases and
injury.
As early as 2005, statistics
showed 2,600 deaths and 330,000
injuries were caused each year by
cell phone distraction.3 As a result, the push to ban certain forms of DWD has been compared to the famous car safety campaigns of the 20th century, including the campaign to mandate the use of seatbelts and to establish a nationwide blood alcohol content limit of.08.
A PET scan, which stands for Position Emission Tomography (it looks at glucose metabolism), is used to
show how the
cells use glucose, as an indication of brain
injury or a marker for brain
injury.