Sentences with phrase «shows early changes»

The new mice, created by researchers at King's College London and the University of Massachusetts Medical School, are particularly strong in showing early changes connected to the development of ALS, Fallon said.

Not exact matches

The chart below shows the percentage changes of the CPPI compared to the same month a year earlier going back to the Financial Crisis.
In early 2015, Ford CEO Fields was preparing to deliver a «change the world» — style speech at CES, the annual consumer electronics trade show, spanning urbanization, the middle class, air quality, and millennials.
A Pew poll predating the accident showed that 66 per cent of Americans support TransCanada's project to link Canada's oilsands to Texas refineries and, I argued earlier this week, there's no reason why they should change their minds.
Bush was suspended from The Today Show when the tape was released, and earlier this year he expressed remorse for not having «changed the subject.»
Indeed, in a classic paper written in the early 1960s, Mundell (Mundell, 1963) showed how, in a world of complete asset substitutability and perfect capital mobility, real interest rates would be largely determined by international market forces with the exchange rate moving in response to changes in domestic monetary policy to provide most of the desired accommodation or tightening.
LONDON — The arrival of the Bank of England's new governor has prompted an immediate change in the voting behaviour of the central bank's policymaking panel, with all nine members deciding to maintain the status quo, minutes to their meeting earlier this month showed Wednesday.
For 2017 and 2018, these forecasts will show little change from our earlier forecasts.
The exchange rate against the US dollar peaked at US68.5 cents in early July, but it subsequently came down quite sharply, falling by almost 4 cents in the middle of the month, and has shown little net change since.
The change is less dramatic for what the Commerce Department calls «intellectual property,» but still the statistics show an increase, a 4.6 percent annualized rate of increase this year so far from 4.2 percent a year during that earlier five - year period.
C. F. Evans writes, «when also it was shown that Mark was the earliest of the Gospels, and that Matthew and Luke had written theirs by reference to his, then the situation was vastly changed.
Here the «contemporized» tradition («Show me your faith apart from your works, and I by my works will show you my faith»; 1:18) appears diametrically opposed to the earlier Pauline formulation unless one takes into account the changed historical context; then differences still remain but they can be viewed as compatiShow me your faith apart from your works, and I by my works will show you my faith»; 1:18) appears diametrically opposed to the earlier Pauline formulation unless one takes into account the changed historical context; then differences still remain but they can be viewed as compatishow you my faith»; 1:18) appears diametrically opposed to the earlier Pauline formulation unless one takes into account the changed historical context; then differences still remain but they can be viewed as compatible.
As a matter of fact, Cobb later qualifies his statement and recognizes «substantive changes» occur between Religion in the Making and Process and Reality.17 Ford, noting Cobb's earlier position, gives a detailed interpretation of seven passages in Religion in the Making to show that Whitehead had not yet ascribed to God physical feeling which allows the contrast between God's temporal and non-temporal natures.18
Harnack set out to show from his penetrating studies of early Christianity that the relevance of Christianity to the modern world lay not in theological dogmatism but in the understanding of Christianity as an historical, changing, evolving process.
I think one of the reasons they did well late in the game last season is because Musgrave was running plays to set up other plays later in the game, like running a play 3 - 4 times early, then showing the same look later while changing it enough to surprise the defense.
It took them a while to figure out what the show was, which you can see in the amount that they completely changed their early marketing campaigns.
The one currently on show at Geneva is just a concept, and the styling is set to change slightly, but the first production examples are set to appear early in 2018.
This is an incredibly difficult question to answer for a variety of reasons, most importantly because over the years our once vaunted «beautiful» style of play has become a shadow of it's former self, only to be replaced by a less than stellar «plug and play» mentality where players play out of position and adjustments / substitutions are rarely forthcoming before the 75th minute... if you look at our current players, very few would make sense in the traditional Wengerian system... at present, we don't have the personnel to move the ball quickly from deep - lying position, efficient one touch midfielders that can make the necessary through balls or the disciplined and pacey forwards to stretch defences into wide positions, without the aid of the backs coming up into the final 3rd, so that we can attack the defensive lanes in the same clinical fashion we did years ago... on this current squad, we have only 1 central defender on staf, Mustafi, who seems to have any prowess in the offensive zone or who can even pass two zones through so that we can advance play quickly out of our own end (I have seen some inklings that suggest Holding might have some offensive qualities but too early to tell)... unfortunately Mustafi has a tendency to get himself in trouble when he gets overly aggressive on the ball... from our backs out wide, we've seen pace from the likes of Bellerin and Gibbs and the spirited albeit offensively stunted play of Monreal, but none of these players possess the skill - set required in the offensive zone for the new Wenger scheme which requires deft touches, timely runs to the baseline and consistent crossing, especially when Giroud was playing and his ratio of scored goals per clear chances was relatively low (better last year though)... obviously I like Bellerin's future prospects, as you can't teach pace, but I do worry that he regressed last season, which was obvious to Wenger because there was no way he would have used Ox as the right side wing - back so often knowing that Barcelona could come calling in the off - season, if he thought otherwise... as for our midfielders, not a single one, minus the more confident Xhaka I watched played for the Swiss national team a couple years ago, who truly makes sense under the traditional Wenger model... Ramsey holds onto the ball too long, gives the ball away cheaply far too often and abandons his defensive responsibilities on a regular basis (doesn't score enough recently to justify): that being said, I've always thought he does possess a little something special, unfortunately he thinks so too... Xhaka is a little too slow to ever boss the midfield and he tends to telegraph his one true strength, his long ball play: although I must admit he did get a bit better during some points in the latter part of last season... it always made me wonder why whenever he played with Coq Wenger always seemed to play Francis in a more advanced role on the pitch... as for Coq, he is way too reckless at the wrong times and has exhibited little offensive prowess yet finds himself in and around the box far too often... let's face it Wenger was ready to throw him in the trash heap when injuries forced him to use Francis and then he had the nerve to act like this was all part of a bigger Wenger constructed plan... he like Ramsey, Xhaka and Elneny don't offer the skills necessary to satisfy the quick transitory nature of our old offensive scheme or the stout defensive mindset needed to protect the defensive zone so that our offensive players can remain aggressive in the final third... on the front end, we have Ozil, a player of immense skill but stunted by his physical demeanor that tends to offend, the fact that he's been played out of position far too many times since arriving and that the players in front of him, minus Sanchez, make little to no sense considering what he has to offer (especially Giroud); just think about the quick counter-attack offence in Real or the space and protection he receives in the German National team's midfield, where teams couldn't afford to focus too heavily on one individual... this player was a passing «specialist» long before he arrived in North London, so only an arrogant or ignorant individual would try to reinvent the wheel and / or not surround such a talent with the necessary components... in regards to Ox, Walcott and Welbeck, although they all possess serious talents I see them in large part as headless chickens who are on the injury table too much, lack the necessary first - touch and / or lack the finishing flair to warrant their inclusion in a regular starting eleven; I would say that, of the 3, Ox showed the most upside once we went to a back 3, but even he became a bit too consumed by his pending contract talks before the season ended and that concerned me a bit... if I had to choose one of those 3 players to stay on it would be Ox due to his potential as a plausible alternative to Bellerin in that wing - back position should we continue to use that formation... in Sanchez, we get one of the most committed skill players we've seen on this squad for some years but that could all change soon, if it hasn't already of course... strangely enough, even he doesn't make sense given the constructs of the original Wenger offensive model because he holds onto the ball too long and he will give the ball up a little too often in the offensive zone... a fact that is largely forgotten due to his infectious energy and the fact that the numbers he has achieved seem to justify the means... finally, and in many ways most crucially, Giroud, there is nothing about this team or the offensive system that Wenger has traditionally employed that would even suggest such a player would make sense as a starter... too slow, too inefficient and way too easily dispossessed... once again, I think he has some special skills and, at times, has showed some world - class qualities but he's lack of mobility is an albatross around the necks of our offence... so when you ask who would be our best starting 11, I don't have a clue because of the 5 or 6 players that truly deserve a place in this side, 1 just arrived, 3 aren't under contract beyond 2018 and the other was just sold to Juve... man, this is theraputic because following this team is like an addiction to heroin without the benefits
This can surely change if Goff shows some improvement during the preseason and early in the year.
If we do get someone who tackles early in the build up because if you tackle late in this league you are shown a card, someone who can stick their head on any type of cross, and someone who can take the space in front of them and charge with the ball, while also having the pace to change directions if there is a counter.
Ainsley Maitland Niles in his two or so matches a CM has shown me that he can protect the back four and attack very well.Why is Wenger destroying the player at LB?I remember also telling everyone here earlier in the season that we should change our formation to four back and that Monreal and Kolasinac shouldn't be in the same team as one has to be rested and deputise for the other.I don't care how consistent Monreal is and to me he has no CB qualities.He at times looks almost world class at LB but to me he has no qualities of a CB.Why is Xhaka also starting?Coquelin is twice the player he is for the role Xhaka should be playing.
I don't see how two mediocre wrs changes the fact we need to finally hit on at least one game changer at wr early and our history shows we can find oline late lall we have to do is look at what Rd Wagner and Alex Lewis we're drafted but if they are cool with getting left in the past with this pre historic style of offense than we will continue to be mediocre
Please you guys should stop this chambers, i really hate Costa for his antics but i watched the match on tv and so the way he behaved throughout the game, i thinkers he has changed... early in the second half Chambers prevented a tap - in from Pedro and ended up landing in post, Pedro left his side only for Diego Costa to show up and check on him #class
The 3 - 1 win which the Blues picked up last season was followed by a home win, but the victory for Pep's men earlier this term showed how the dynamic has changed between these two.
Add that to Jack Cork's England debut earlier this season, which followed on from Tom Heaton and Michael Keane becoming England internationals, and it certainly shows things are changing significantly at Burnley Football Club.
Support groups can be great for these early days, since you can often show up late, nurse your baby or change them, try to comfort a crying infant, etc, without it being a big deal since everyone is in the same situation.
In other words, even when home visitation programs succeed in their goal of changing parent behaviour, these changes do not appear to produce significantly better child outcomes.21, 22 One recent exception, however, was a study of the Home Instruction Program for Preschool Youngsters (HIPPY) model with low - income Latino families showing changes in home parenting and better third - grade math achievement.23 Earlier evaluations of HIPPY found mixed results regarding program effectiveness.
Scores of animal and human studies show that early life stress, such as severe early social deprivation, leads to long - term changes in the brain, cognitive and social problems, and heightened susceptibility to anxiety, depression, and drug abuse in adulthood.
Longitudinal research using these techniques shows that although genetic factors primarily account for developmental continuity, some evidence can be found for genetic contributions to change, especially during the transition from early to middle childhood (Fulker, Cherny, & Cardon, 1993) and perhaps from middle childhood to late adolescence (Loehlin, Horn, & Willerman, 1989).
But «there is a whole group of women and doctors who are delivering early for convenience or due to a very minor change in some test that has not been shown to be helpful,» he says.
«While studies have shown that changing the admissions process will not increase diversity, we know that increasing access to resources from an early age will.»
On the East Coast, Fall is slowly, belatedly settling in — the sky darkens early now, the leaves show signs of withering, and the mind naturally turns to questions of change.
The numbers are a change from earlier in the year, when a poll showed the majority of voters said they were in favor of holding a constitutional convention, despite the fact that they had not heard much about it.
Mr. Espaillat's filing shows that he has yet to pay rent for the use of the Northern Manhattan Democrats for Change office his campaign is using as its headquarters, and that he owes $ 3,500 to consulting group Bedford Grove for holding a fund - raiser for him earlier this month.
Yet the snapshot of 2000 Britons, taken by YouGov for the Fabian Society earlier this month, also shows that voters north of the border are the strongest advocates when it comes to certain changes.
nice speech man, but you need to patient with this we all not happy with their policy, but let them fail totally before you come to show, don; t kill your ambition early, make sure you change ekiti and turn it to mega city, so therefore your work will speak for you and you will be able make all Nigerian proud on you
Focused on delivering an on - time spending plan — which polls earlier this month showed 62 percent of voters wanted the timely budget, stronger ethics laws be damned — the governor and legislators jettisoned plans for a minimum wage hike, the Dream Act and changes to the criminal justice system from the spending plan.
Speaking to BBC One's The Politics Show, Jon Cruddas said the «magic» of Tony Blair's early years had changed into an «extraordinary» resilience.
Duke scientists have shown that it's possible to pick out key changes in the genetic code between chimpanzees and humans and then visualize their respective contributions to early brain development by using mouse embryos.
Climate change may harm early - flowering plants not through plant - pollinator mismatch but through frost damage, a Dartmouth College - led study shows.
A study published yesterday in Nature Climate Change showed that early exposure to high levels of CO2 during the larval stage of development had significant negative effects on the fish's size, metabolism and ability to sense threats in their environment.
Scanning back through complete publication lists (not the censored ones on scientists» own Web sites) shows just how frequently people change direction early in their scientific careers.
Our study shows that after that early programming state, after weaning, and after the lactation period, when we introduced a new type of diet it changed the epigenome in a way that actually affects metabolism and potentially will reduce some of the damage caused by an early - life high - fat exposure,» Pan says.
Studies including Wang's earlier work in Africa have shown that even small changes in soil moisture in drylands could be significant enough to cause large changes in vegetation productivity.
While the documents show API learned of potential climate change risks as early as 1968 and had formed committees to examine smog pollution in the 1940s, Exxon CEO Lee Raymond said in November 1996 that climate science was unsettled.
On the western side the ice cores showed deposits of PFASs initially increasing as they were used more and more in European industry in the 1980s, and then decreasing as industrial output changed in the early 2000s.
Patients who had changed versions of this gene showed early promise, often attending college, but then experienced cognitive decline consistent with a degenerative disease.
Earlier work has shown that epididymis cells release small packets filled with RNA that can fuse to sperm and change their genetic payload.
4 Some things never change: Edison's early film loops included one showing «cooch» dancers; another reenacted the decapitation of Mary, Queen of Scots — arguably the first horror flick.
A recent study published earlier this month in Nature Climate Change by University of Georgia demographer Mathew Hauer showed that Florida could lose as many as 2.5 million people to sea - level rise by the end of the century.
a b c d e f g h i j k l m n o p q r s t u v w x y z