Sentences with phrase «shows human endothelial cells»

Not exact matches

In experiments conducted on human lung endothelial cells and in mice, the researchers showed that NS1 caused permeability of the endothelium, which lines the walls of blood and lymph vessels.

Specifically, the study — reported online in The Journal of Infectious Diseases — shows that E. coli K1 modulates the protein peroxisome proliferator - activated receptor - gamma (PPAR - γ) and glucose transporter - 1 (GLUT - 1) levels at the blood - brain barrier in human brain microvascular endothelial cells.

Professor Takao Hamakubo's group at the Department of Quantitative Biology and Medicine, Research Center for Advanced Science and Technology (RCAST), have shown that PTX3 forms strong bonds with histones and partially unfolds, leading to a disordered coaggregation of histone and PTX3 and protecting human endothelial cells from damage.

In keeping with this, recent studies showed that flavanols, a subclass of flavonoids that is richly represented in natural cocoa beans, increase NO production by cultured human vascular endothelial cells (16) and improve endothelium - dependent vasorelaxation (NO - dependent) in finger (2) and brachial (3) arteries of healthy humans.

Figure 2 shows sets of results for four areas of human corneal endothelial tissue; central endothelium (defined by endothelial cells within a 4 mm trephined boundary), central - intermediate endothelium (defined by endothelial cells within an 8 mm trephined boundary), intermediate - peripheral endothelium (defined by endothelial cells between the 4 mm trephine edge and 12 mm from the center of the corneal endothelium), and the peripheral endothelium (defined by the 8 mm trephined edge and 12 mm from the center of the corneal endothelium).

When human corneal endothelial cells were stimulated with EGF following wounding, staining also appeared in the periphery (not shown).

Figure 4 shows the mean survival curves obtained with the MTT assay in human umbilical vein endothelial cells (HUVEC), under conditions of normal and low proliferation rates (20 % and 2 % of FBS).

This effect on cell survival was not endothelial cell - specific, since IC50 values for kahweol treatment of several human tumoral cell lines were similar to those obtained for HUVEC (results not shown).

Human pulmonary artery endothelial cells cultured with serum from homozygous carriers showed an increase in MCP - 1 release in carriers of the minor allele, with the difference eliminated upon addition of tocilizumab.

There have, however, been some studies with encouraging results; for example, Chinese scientists took human endothelial progenitor cells exposed to resveratrol, and showed that telomerase activity increased.