Sentences with phrase «sickle cell disease at»

«Secondary benefits of this trial include the significant improvement in clinical care for children with sickle cell disease at each of the 29 sites because each location had a designated hematologist, neurologist, neuroradiologist and psychologist working as a team to identify and decrease further injury to the brain in this vulnerable population.»

Not exact matches

bluebird bio (BLUE)- The company's BCMA CAR - T drug candidate bb2121 remains attractive despite overblown fears on durability (peak sales of $ 2 billion or more), LentiGlobin has a good shot at success in TDT (Transfusion - Dependent ß - Thalassemia) and SCD (Severe Sickle Cell Disease), and they have a strong cash position.

Government funding for research into sickle - cell disease is pitifully inadequate (the Sickle - Cell Society receives no government funds atsickle - cell disease is pitifully inadequate (the Sickle - Cell Society receives no government funds at acell disease is pitifully inadequate (the Sickle - Cell Society receives no government funds atSickle - Cell Society receives no government funds at aCell Society receives no government funds at all).

Breech Twins and higher order multiples Previous CS Pre-Eclampsia Placenta praevia Cervical incompetence Previous late stillbirth Previous premature birth Grand multiparty Age under 18 Age over 35 Smoking Drug use Severe mental health issue Epilepsy Type 1 diabetes Type 2 diabetes Gestational diabetes Asthma GBS positive Abnormal antibodies Transplant recipient Congenital heart disease Known foetal abnormality Immunosuppressive medication MS Physical disability Intellectual disability Hypothyroidism Hyperthyroidism Previous shoulder dystocia Previous 3rd or 4th degree tear Sickle Cell anaemia BMI under 18 or over 35 at conception Previous massive PPH APH in current pregnancy HIV / AIDS Hepatitis B or C Active TB IUGR Oligohydramnios Polyhydramnios Child previously removed from custody because of abuse Uterine abnormalities such as uterine septum or double uterus Previous uterine surgery for fibroids Chronic renal problems Hypertension Auto immune condition Previous stroke or blod clot Cancer Domestic violence or abusive home Prisoners Homeless women

(borrowed from Dr Kitty) Breech Twins and higher order multiples Previous CS Pre-Eclampsia Placenta praevia Cervical incompetence Previous late stillbirth Previous premature birth Grand multiparty Age under 18 Age over 35 Smoking Drug use Severe mental health issue Epilepsy Type 1 diabetes Type 2 diabetes Gestational diabetes Asthma GBS positive Abnormal antibodies Transplant recipient Congenital heart disease Known foetal abnormality Immunosuppressive medication MS Physical disability Intellectual disability Hypothyroidism Hyperthyroidism Previous shoulder dystocia Previous 3rd or 4th degree tear Sickle Cell anaemia BMI under 18 or over 35 at conception Previous massive PPH APH in current pregnancy HIV / AIDS Hepatitis B or C Active TB IUGR Oligohydramnios Polyhydramnios Child previously removed from custody because of abuse Uterine abnormalities such as uterine septum or double uterus Previous uterine surgery for fibroids Chronic renal problems Hypertension Auto immune condition Previous stroke or blod clot Cancer Domestic violence or abusive home Prisoners Homeless women

A team of researchers at the Stanford University School of Medicine has used a gene - editing tool known as CRISPR to repair the gene that causes sickle cell disease in human stem cells, which they say is a key step toward developing a gene therapy for the disorder.

Researchers from Howard University will present their findings today at the American Physiological Society's Physiological and Pathophysiological Consequences of Sickle Cell Disease conference in Washington, D.C.

Alan Flake at The Children's Hospital of Philadelphia (CHOP) in Pennsylvania is planning a similar clinical trial of maternal stem cells in fetuses with sickle cell anemia, a painful, debilitating disease that often shortens life.

«New technology may standardize sickle cell disease screening for infants: UH Case Medical Center experts present new data at Annual Meeting of the American Society of Hematology.»

In a poster presentation (Abstract # 3379), Yunus Alapan, Umut Gurkan PhD and Jane Little, MD presented promising findings related to new technology aimed at facilitating early detection of sickle cell disease for infants in developing countries.

Like Paizley Carwell - Bowen, Hina underwent transplantation at Children's Hospital of Los Angeles to treat her sickle - cell disease.

Patients with sickle cell disease are commonly prescribed a daily, long - acting painkiller taken at a constant dose, and a short - acting painkiller to be taken as needed for episodes of more severe pain.

To assess risk, Thomas Adamkiewicz, codirector of the Hemoglobinopathy / Genomics Training Program at Morehouse School of Medicine in Atlanta, surveyed four medical centers and found that seven children with sickle - cell disease had been treated with umbilical cord blood from unrelated donors.

He would spend his Saturday mornings in the lab conducting microbiology experiments and got exposed to the science of DNA during a summer internship at the university's Center for Sickle Cell Disease.

An international research team led by biochemists at The University of Texas Health Science Center at Houston (UTHealth) reduced the sickling of red blood cells in a mouse model of the disease.

Rod Kellems, Ph.D., study co-author and chairman of the Department of Biochemistry and Molecular Biology at the UTHealth Medical School, added, «This research provides insight into how red blood cells work, revealing that SphK1 - mediated elevation of S1P contributes to sickling and promotes disease progression and highlights potential therapeutic opportunities for sickle cell disease.»

Similarly, carriers in the Jackson study of one copy of the genes that cause sickle - cell disease — a useful trait against malaria in Africa — appear to be more at risk for kidney disease.

A new study in the Journal of Clinical Sleep Medicine revealed that 44 percent of adults with sickle cell disease who report trouble sleeping actually have a clinical diagnosis of sleep disordered breathing, including sleep apnea, which lowers their oxygen levels at night.

Researchers at Johns Hopkins have successfully corrected a genetic error in stem cells from patients with sickle cell disease, and then used those cells to grow mature red blood cells, they report.

Colleen Dansereau, RN, MSN, CPN Program Manager, Gene Therapy Program As manager of the Gene Therapy Program, Colleen administratively manages the CAR T - cell therapy program as well as all administrative responsibility for all of the gene therapy clinical trials that take place at Dana - Farber / Boston Children's, for conditions including sickle cell disease, Wiskott - Aldrich Syndrome (WAS), and chronic granulomatous disease (CGD).

This year's Action Award honorees include global leaders in the fight to end cancer as we know it; a world leader in advancing the emerging field of regenerative medicine and game - changing cell therapy medical treatments; the president of a non-profit group focused on developing cures for chronic, debilitating and fatal diseases; a sickle cell and stem cell advocate and founder / science administrator of the Axis Advocacy; and the founding director of the Institute for Integrated Cell - Material Sciences (iCeMS) at Japan's Kyoto Universcell therapy medical treatments; the president of a non-profit group focused on developing cures for chronic, debilitating and fatal diseases; a sickle cell and stem cell advocate and founder / science administrator of the Axis Advocacy; and the founding director of the Institute for Integrated Cell - Material Sciences (iCeMS) at Japan's Kyoto Universcell and stem cell advocate and founder / science administrator of the Axis Advocacy; and the founding director of the Institute for Integrated Cell - Material Sciences (iCeMS) at Japan's Kyoto Universcell advocate and founder / science administrator of the Axis Advocacy; and the founding director of the Institute for Integrated Cell - Material Sciences (iCeMS) at Japan's Kyoto UniversCell - Material Sciences (iCeMS) at Japan's Kyoto University.

At the ISSCR 2016 meeting in San Francisco, attendees heard two inspirational stories from Kristin Macdonald and Adrienne Bell - Cors of what it's like to live with diseases such as retinitis pigmentosa (RP), and sickle cell disease, respectively.

Corn's lab is one of several using CRISPR to cure — at least in isolated cells and mice — sickle cell disease, where a single - letter DNA mutation stymies the oxygen - ferrying capacity of red blood cells.

Endocrinologist Vin Tangpricha notes that Emory studies are looking at vitamin D in the context of tuberculosis, sepsis, sickle cell disease, cancer, cystic fibrosis and pain sensitivity.

Children receiving care at Texas Children's Sickle Cell Program have the opportunity to participate in several National Institutes of Health (NIH)- funded research studies led by physician scientists, providing the latest treatments for this disease.

The Sickle Cell Program conducts state - of - the - art clinical and laboratory research aimed at gaining a better understanding of the disease, preventing its complications and ultimately finding a cure.

Mini Transplant May Reverse Severe Sickle Cell Disease Results of a preliminary study by scientists at the National Institutes of Health and Johns Hopkins show that «mini» stem cell transplantation may safely reverse severe sickle cell disease in aSickle Cell Disease Results of a preliminary study by scientists at the National Institutes of Health and Johns Hopkins show that «mini» stem cell transplantation may safely reverse severe sickle cell disease in aduCell Disease Results of a preliminary study by scientists at the National Institutes of Health and Johns Hopkins show that «mini» stem cell transplantation may safely reverse severe sickle cell disease in Disease Results of a preliminary study by scientists at the National Institutes of Health and Johns Hopkins show that «mini» stem cell transplantation may safely reverse severe sickle cell disease in aducell transplantation may safely reverse severe sickle cell disease in asickle cell disease in aducell disease in disease in adults.

LA JOLLA, CA — Researchers at the Salk Institute for Biological Studies have developed a way to use patients» own cells to potentially cure sickle cell disease and many other disorders caused by mutations in a gene that helps produce blood hemoglobin.

Sickle cell anemia is a genetic disease, says Damiano Rondelli, MD, the Michael Reese Professor of Hematology at the University of Illinois College of Medicine at Chicago.

People with sickle cell disease living in the malaria belt had more grandchildren than those around them in their area at the time the trait became widespread.

Just as children of Jewish descent are more likely to have Tay Sachs disease and African Americans are more likely to have sickle cell anemia, so children with certain characteristics are at greater risk of becoming jaundiced.

Phenotype and Epidemiological Profile of Children with Sickle Cell Disease Followed - Up at the Mother and Child Hospital of N'Djamena