Sentences with phrase «side chain with»

start from the 39 min mark he says there will be a side chain with ANOTHER COIN THAT WILL BE HAND IN HAND WITH VERGE!!!! THAT MEANS A DROP FOR A ONE TO ONE RATIO!!!

Using sazetidine - A as a template, medicinal chemists developed multiple series of novel ligands with modifications to the pyridine core, azetidine ring, and alkynyl side chain with the objective of designing α4β2 - nAChR partial agonists of high specificity.

Replacement of the side chain with an isopropyl group led to the most potent compound 88, showing an IC50 of 2 nM for antiviral activity and suitable pharmacokinetic properties.

The picture below shows how to fix the elastic: we fix the side chains with carbines and connect it to the elastic band, and fix it in the ring with a clip that connects to the vertical chain (which goes through the hair extensions).

Not exact matches

Napster co-founder Sean Parker's proposal to sell first - run movies to home viewers at $ 50 a pop has stirred up various corners of Hollywood, with big movie studios and theater chains up in arms over the Screening Room idea while multiple major filmmakers have landed on opposing sides of the argument.

In an effort to align the two cultures, now nearly every week a team from New York — distribution, product development, supply chain, IT — flies to Germany to work side by side with the Eisfeld team, and vice versa.

He also innovated on the supply - chain side, sharing the rich customer data generated by his direct sales with his suppliers — an unprecedented move that enabled Dell to deliver computers almost in real time, keeping costs and inventories low.

The chain has been working to appeal to customers beyond coffee and doughnuts, with new menu items such as a crispy chicken sandwich and side dishes to boost breakfast and lunch sales.

When Cara Operations merged with Fairfax Financial's Prime Restaurants in October, the 130 - year old company cemented its grip on Canada's casual dining market by adding East Side Mario's and Casey's to an arsenal that already included nationwide chains like Swiss Chalet and Milestones.

The chain also just started testing family - style meals with two new sides: macaroni and cheese and baked beans.

The Italian chain is serving a traditional turkey dinner with Italian sides and desserts including bruschetta, gnocchi and tiramisu.

At the top, there are the networks (Visa, MasterCard, etc.), who enjoin issuers (banks) and brokers to deal with their respective sides of the chain.

On the flip side, a separate study by the GT Nexus, a supply chain platform, found that 75 percent of U.S. adults have come across an unavailable product in stores over the past year, with 63 percent encountering that issue online.

It's actually a separate anonymous currency that's designed to live side - by - side with Bitcoin on the same block chain.

Red Robin is known for great gourmet hamburgers and tasty cocktail concoctions, but the 400 - plus - unit chain also serves a huge tower of onion rings that comes with a side of this creamy, sweet - and - smoky dipping sauce.

On the beverage side, the chain is participating in the craft beer movement, with an average of 24 tap handles at most locations.

At present, these retail - side offerings do not converge with barcoding technologies such as RFID that are used across the value chain for product tracking and inventory management.

That caused a chain reaction in terms of player roles with Can moving in to the role occupied previously by Wijnaldum and Wijnaldum himself moving over to the right hand side of the central midfield to take the role vacated by Lallana.

First up for Arsenal is a home encounter with Chelsea, the defending Premier League champions, the side Arsene Wenger's Gunners are aiming to dislodge from the top of the food chain.

Vandals hacked 15 cottonwood trees with a chain saw at a nature area within Burnham Park on Chicago's South Side, Park District officials said Wednesday.

When you have finished a feeding session move the safety chain attached with the other charm to either the «L» bead for the left side or the «R» bead for the right side to keep track of which breast the baby nursed off of last.

With the merger at its foundation, FoodCorps is launching a rigorous supply - side initiative focused on improving the school meals supply chain.

Stringer's drift toward the pragmatic center has taken place as his Upper West Side base has itself grown wealthier, with chain stores taking the place of local shopowners and billionaires moving into 15 Central Park West.

Moskowitz's Success Academy charter school chain is looking to create a new Upper West Side school to open in the fall of 2014, along with five other schools across the city, and representatives said they're seeking input before moving forward with the plan.

Eva Moskowitz's Success Academy charter school chain is under fire from all sides for its harsh discipline policies and treatment of students with special needs.

They are also all saturated fats, chains of single - bonded carbon atoms with hydrogen atoms neatly lined up on either side of each carbon.

This Cuban link chain with diamonds is a little on the shorter side at 22 inches.

Grate needed three things to mimic proteins: raw components with a backbone that can support a large variety of side chains; the ability to put the side chains in a particular order; the stickiness, which chemists refer to as non-covalent bonds.

They made a variety of monomers by adding different side chains to cyanuric chloride, with each monomer a single building block analogous to an amino acid.

It typically takes many years to initiate such trials because of the stringent safety testing that must be done before testing in humans begins, but Reynolds said it may be possible to move faster as the therapy only involves modifying a patient's dietary intake and supplementing with a medium - chain triglyceride oil, both of which have no known side effects.

Polymers are strings of molecules with a central backbone and may contain side chains called «pendant groups» that dangle from the central structure.

They have synthesized a physically cross-linked elastomer composed of a central block onto which side chains are grafted (like a bottle brush) and with linear terminal blocks at each end.

In a protein the cogs and springs are the molecules that make it up: amino acids form its backbone each with side - chains of different molecules branching out on all sides in three dimensions.

The team modified a n - type conjugated polymer with semi-fluoroalkyl side chains — which are found to have several unique properties, such as hydrophobicity, rigidity, thermal stability, chemical and oxidative resistance, and the ability to self - organize.

In the new study, the researchers were able to determine that the water molecules directly touched the protein's «side chains,» the portions of the protein molecule that bind and unbind with each other to enable folding and function.

Images produced by the study clearly show the structure of the proteasome complex — with the protein backbone of each of its 28 subunits visible along with most of the side chains of the proteins.

These are simulated crystal structures of virgin - DEB and T4H - DEB (chemically known as 1,4 - distyrylbenzene, a trans - isomer of DEB intermediate product after the capture of first 4 atomic hydrogen with 2 CH bonds on opposing sides of the carbon chain).

With a few simple alterations to the side chains that branch out from the polymer backbone, the researchers were able to create a shape - shifting version of the hole - punching agent.

In this case, the handholds are the amino acid side chains of a protein that will interact with other proteins or small molecules, and the body is the folding of the protein that incorporates all the amino acids into one structure.

A number of different domain types interact with histone tails to read, write or erase protein side chain modifications.

Interestingly, the unique mass feature identified in our nontargeted assay of bsl1 - 1 inflorescences is consistent with a C21 pregnane that would result from side chain cleavage (Kolbe et al., 1994)(Supplemental Figure 6).

Since two stereocenters were present in the structure, the initially mixture of four stereoisomers was subsequently separated into the single components to evaluate the effects associated with the absolute configuration of the side chains.

With more than 120 members coming from the 3 sides of the knowledge triangle - universities, research organisations, and industry - the EIT RawMaterials Knowledge and Innovation Community has initiated radical innovation in the critical materials value chains for the benefit of the European society and beyond - from mine to market.

Due to the free rotation of the side - chains, it was not straightforward to define the mutual spatial relationships among the functional groups, although previous studies had reported the fixed distances between Cβ atoms substituted with key functional groups on the rigid cyclic peptide nucleus.

Further modifications focused on the replacement of the side chain methyl group with several alternative substituents.

The replacement of the Arg3 - Nal4 peptide bond with an (E)- alkene isostere in compound 7 produced a negative effect on CXCR4 inhibitory activity, probably due to the lack of H - bonding of amide moiety and a different interaction of pseudo -1,3-allylic strain between the Arg3 carbonyl group and the Nal4 side chain.

The Meiler laboratory leads the further development of ROSETTALIGAND (Meiler, J.; Baker, D. «ROSETTALIGAND: Protein - small molecule docking with full side - chain flexibility»; Proteins 2006; 65; 538 - 548).

The chromophore establishes hydrogen bonds with water molecules and side chains of the adjacent amino acids as well as van der Waals contacts, all of which influence its fluorescent properties.

Hemicellulose is a shorter chain polysaccharide with a -(1g4) backbone and numerous covalently bound branching side chains.

Amongst the 22 amino acids vital for our body to function and manufacture proteins, glycine is the smallest and simplest, with only a single hydrogen forming its side chain.