The next are medical treatments for hyperthyroidism (designed to slow the thyroid), radiation treatment for cancers of the head and neck, thyroid surgery (removal of some or all of the gland), or
side effects of drugs for other conditions.
Not exact matches
These risks and uncertainties include, among others: the unfavorable outcome
of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any
of our products or products using our proprietary technologies, which may lead to competition from generic
drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components
of our filings
for our products, including our clinical trial designs, conduct and methodologies and,
for ALKS 5461, evidence
of efficacy and adequacy
of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results
of our clinical development activities may not be positive, or predictive
of real - world results or
of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement
for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights
of third parties, or have unintended
side effects, adverse reactions or incidents
of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.
The new offering, «Watson
for Patient Safety,» will gobble up anonymized medical records, claims data, and millions
of electronic submissions to the FDA about potential
drug side effects (known as individual case safety reports) to see if it can learn about the hidden dangers
of medicines before they become too costly.
In addition to partnering with Celgene (celg) to better track negative
drug side effects, IBM (ibm) is applying its cognitive computing AI technology to recommend cancer treatment in rural areas in the U.S., India, and China, where there is a dearth
of oncologists, said Deborah DiSanzo, general manager
for IBM Watson Health.
Agios Pharmaceuticals shares plunged more than 18 percent after the company discontinued development
of an experimental
drug for rare blood disorder due to
side effects seen in a study.
She said that employers» increased use
of high - deductible plans, one
of the
side -
effects of the law, has resulted in patients paying more out
of pocket
for the
drug, and that's «where you're seeing a lot
of noise around EpiPen.»
Martin Shkreli, the founder and chief executive
of Turing, said that the
drug is so rarely used that the impact on the health system would be minuscule and that Turing would use the money it earns to develop better treatments
for toxoplasmosis, with fewer
side effects.
The existing
drugs for osteoarthritis cause a high frequency
of stomach ulcers and other
side effects such as high blood pressure.
ALKS 3831 is a treatment
for schizophrenia that avoids the
side effects of weight gain and metabolic problems that the incumbent
drug has, and a phase 3 trial
for it should read out in the fall
of 2018.
Many would argue that it's possible
for her to feel better without taking
drugs: she could try the «talking cure» (regular sessions with a counselor), or an alternative treatment such as herbal or light therapy If she goes to an M.D., though, she'll likely carry my a prescription
for an antidepressant such as Prozac or Zoloft — one
of these brave new medicines that promise such good results with so few
side effects,
• PLIVA vs. Mensing: Ruled that makers
of generic
drugs can not be sued
for failing to warn patients
of new dangers or
side effects.
When inflammation strikes, we are conditioned into reaching
for a quick fix in the way
of pharmaceutical or prescribed
drugs such as aspirin and ibuprofen, temporary panacea's that come with their own adverse
side effects and with long term use have the potential to create a host
of health problems independently.
This was before Mackey had won a single Iditarod, let alone four straight; before he used what he calls his marathon style — catnapping as his sled moves and covering 100 - mile chunks at a moderate pace without prolonged rest, instead
of sprinting from rest stop to rest stop like most other racers — to win an unprecedented double (the Yukon Quest, the world's other 1,000 - mile dogsled race, and just weeks later the Iditarod) not once but twice; before he became so dominant that slower competitors complained they had no chance to finish within five days
of him (the requirement
for an official place and a commemorative belt buckle); and before a rival pushed
for drug testing at the 2010 Iditarod, suspecting that Mackey's secret was his prescription
for medical marijuana to alleviate the
side effects of cancer treatment.
However there are a few
drugs which are known
for causing extra or spontaneous milk flow (known as galactorrhea) as a
side effect of their intended medical use.
Moms have fewer
drugs or no
drugs and experience less interventions and complications which means less risk
of side effects for mom and baby
Although amoxicillin is safe
for most babies and situations that call
for antibiotics, there is a chance
of side effects, like with most
drugs.
Many
of the epidural
side effects mentioned below are not improved with low - dose or walking epidurals, because women using these techniques may still receive a substantial total dose
of local anesthetic, especially when continuous infusions and / or patient - controlled boluses (single large doses) are used.34 The addition
of opiate
drugs in epidurals or CSEs can create further risks
for the mother, such as pruritus (itching) and respiratory depression (see below).
Other common
side effects of epidurals include: inability to pass urine (and requirement
for a urinary catheter)
for up to two - thirds
of women; 38 itching
of the skin (pruritus)
for up to two - thirds
of women administered an opiate
drug via epidural; 39, 40 shivering
for up to one in three women; 41 sedation
for around one in five women; 42 and nausea and vomiting
for one in 20 women.43
The
side effects of the
drug being used constantly results in the need
for a C - section.
Sources: American Society
for Reproductive Medicine, «Fact Sheet:
Side -
effect of injectable fertility
drugs,» revised 2012.
Many moms use fewer
drugs or no
drugs, which means less risk
of side effects for you and your baby, due to elimination
of the
Mothers should enter into labor and delivery informed about the stages
of labor,
drug - free ways to cope with labor pain, potential
side effects of labor medications, and benefits
for mother and baby
of immediate and exclusive breastfeeding.
«This discovery opens the way
for the rational design
of a new generation
of antipsychotic
drugs, hopefully with more desirable
effects and fewer
side effects.»
Hannes Stockinger, the senior author
of the study, adds: «If we coupled this delivery method with screening
of patient's tumours
for the presence
of a unique surface protein, which we can target with the Fab fragment - functionalized liposomes, we might be able to treat tumours more efficiently and decrease the
side effects of the delivered anti-cancer
drugs substantially.
But while the
drug had few
side effects, it wasn't an effective treatment
for either
of the diseases.
While the once - daily dosing, low
side -
effects profile, and shortened treatment duration
of interferon - free direct - acting antivirals are ideal
for injection
drug users, most trials
of these therapies
for HCV have excluded persons with recent injection
drug use.
Dr. McCabe said nanoparticles are a leading - edge technology also being studied
for delivery
of drugs for other conditions, such as cancer, heart disease, and bacterial infections, in order to target specific cells to reduce toxicity and
side effects of those medications and to make them more effective.
Some methods may be good at providing positive evidence that a
drug works,
for example, but other types
of studies may be better at finding evidence that it doesn't — or that it also causes unacceptable
side effects.
Not all chemotherapy
drugs are equally effective
for all people, and finding the best treatment
for an individual is a painful process
of trial and error that wastes time and exposes patients to toxic
side effects.
Stated differently, 98
of 100 men treated
for five years would receive no benefit from the
drug, yet they would all be exposed to risk
of its potentially serious and fatal
side effects, such as muscle breakdown and kidney failure.
The law also calls
for a new database that would scan hospital and insurance records
for trends in
side effects of certain
drugs and include data from 25 million patients by 2010.
The JDF Center
for Islet Cell Transplantation will fund 32 researchers to focus on four main goals: Reversing the overactive immune response that kills islet cells; finding new sources
for islet cell transplants, such as pigs or genetically engineered cells; persuading the body to accept the transplanted cells without immunosuppressive
drugs that often trigger worse
side effects than the disease; and overcoming the technical difficulties
of transplantation.
But
for around a third
of rheumatoid arthritis patients, these
drugs either fail or produce intolerable
side effects, says Paul Friedman, chief executive
of Incyte.
«Since epalrestat is already on the market and has no major adverse
side effects, our study provides a proof
of principle that it could become a valuable targeted
drug for the clinical treatment
of basal - like breast cancer,» Dong says.
In phase I trials, researchers test a new
drug or treatment in a small group
of people
for the first time to evaluate its safety, determine a safe dosage range, and identify
side effects.
But
for transplant recipients, one prospect has remained unchanged: a lifetime
of taking powerful
drugs to suppress the immune system, a treatment that can have serious
side effects.
The challenge,
of course, is to somehow meld a bewildering array
of data sets: all sorts
of historic and current medical records about each person and all sorts
of scientific reports on a number
of drugs,
drug tests, potential
side effects and outcomes
for other patients.
13 After a 1992
drug trial in the Welsh mining town
of Merthyr Tydfil, male subjects reported that sildenafil citrate hadn't done much
for their angina, but it did have an unusual
side effect on another part
of their anatomy.
For most of the past 20 years, therapies for hepatitis C relied on interferon drugs, which require regular injections for as long as one year and trigger miserable, flu - like side effects that prompt many patients to quit the regim
For most
of the past 20 years, therapies
for hepatitis C relied on interferon drugs, which require regular injections for as long as one year and trigger miserable, flu - like side effects that prompt many patients to quit the regim
for hepatitis C relied on interferon
drugs, which require regular injections
for as long as one year and trigger miserable, flu - like side effects that prompt many patients to quit the regim
for as long as one year and trigger miserable, flu - like
side effects that prompt many patients to quit the regimen.
Once the FDA green - lights a
drug and it is ushered into the hands (and IVs)
of patients, there is no real incentive
for a company to continue to collect information about
side effects in any systematic way.
Calcium is a «promiscuous» signal used by all cells
for a wide variety
of processes, he notes, and thus
drugs that target it could have major
side effects.
In a final year project, MChem undergraduate student Edward Howe, working in Professor David Smith's research team in the Department
of Chemistry at York looked
for a way
of eliminating the adverse
side -
effects associated pain - killing
drugs, particularly in the stomach, and the problems, such as ulceration, this could cause patients.
For example, light - activated switches can fine - tune anti-cancer
drugs, so they target only cancer cells and not healthy ones, thereby eliminating the
side effects of chemotherapy.
The combination
of the two
drugs could potentially shorten treatment time, reduce the
side effects of bedaquiline and improve patient outcomes
for those suffering from TB.
In the next month, they will begin searching
for about 45 volunteers who have severe hearing loss, most likely caused by the
side effects of drugs.
New findings by UH biomedical engineer Chandra Mohan and his team raise hope
for a new class
of drugs to treat lupus that may not include the long list
of adverse risks and
side effects often associated with current treatments.
New findings by a biomedical engineer and his team at the University
of Houston (UH) raise hope
for a new class
of drugs to treat lupus that may not include the long list
of adverse risks and
side effects often associated with current treatments
for this disease.
I wonder how many people with slightly elevated cholesterol would feel this rather minimal risk reduction to be worth the cost and the potentially bad
side effects of taking this type
of drug for the rest
of their lives.
«The results
of this study point to the potential
for an alternative treatment that avoids the typical
drug side effects, such as bloating and electrolyte imbalance, by imitating the body's natural physiology.»
After incurring a 12 - count federal indictment
for «withholding information and making false statements» to the U.S. Food and
Drug Administration (FDA) about side effects of its anti-cholesterol drug Triparanol, Merrell had to pay fines and pull it off the mar
Drug Administration (FDA) about
side effects of its anti-cholesterol
drug Triparanol, Merrell had to pay fines and pull it off the mar
drug Triparanol, Merrell had to pay fines and pull it off the market.