Sentences with phrase «sided use of evidence»

Giving providers assurance that guidelines can be used only in their favor may be an important step toward gaining their support; but allowing such one - sided use of evidence in a court of law raises disturbing questions of fairness and of validity under the U.S. Constitution's Fifth and Fourteenth Amendments» due process and equal protection mandates, and under state constitutional principles as well.

Not exact matches

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

The weight of evidence, then, seems to he on the side of those who hold to the view expressed by Carroll A. Wise, of Garrett Theological Seminary «The belief that the excessive use of alcohol is simply a matter of habit is no longer scientifically tenable.»

Whilst van Gaal admitted that his side created more when playing four in midfield, as shown by their two second half goals in West London, he also suggested that it allows them less «control» of the game — using the chances that QPR created themselves in the second half as evidence:

The prone or side sleep position can increase the risk of rebreathing expired gases, resulting in hypercapnia and hypoxia.54, — , 57 The prone position also increases the risk of overheating by decreasing the rate of heat loss and increasing body temperature compared with infants sleeping supine.58, 59 Recent evidence suggests that prone sleeping alters the autonomic control of the infant cardiovascular system during sleep, particularly at 2 to 3 months of age, 60 and can result in decreased cerebral oxygenation.61 The prone position places infants at high risk of SIDS (odds ratio [OR]: 2.3 — 13.1).62, — , 66 However, recent studies have demonstrated that the SIDS risks associated with side and prone position are similar in magnitude (OR: 2.0 and 2.6, respectively) 63 and that the population - attributable risk reported for side sleep position is higher than that for prone position.65, 67 Furthermore, the risk of SIDS is exceptionally high for infants who are placed on their side and found on their stomach (OR: 8.7).63 The side sleep position is inherently unstable, and the probability of an infant rolling to the prone position from the side sleep position is significantly greater than rolling prone from the back.65, 68 Infants who are unaccustomed to the prone position and are placed prone for sleep are also at greater risk than those usually placed prone (adjusted OR: 8.7 — 45.4).63, 69,70 Therefore, it is critically important that every caregiver use the supine sleep position for every sleep period.

Because of the potential for suffocation, entrapment, and strangulation and lack of evidence to support that bumper pads or similar products that attach to crib slats or sides prevent injury in young infants, the AAP does not recommend their use.

While the researchers found evidence supporting the use of medical cannabinoids to be limited, side - effects were both common and consistent.

There is plenty of anecdotal evidence out there claiming a link between cell phone use and cancer: Keith Black, chairman of neurosurgery at Cedars - Sinai Medical Center in Los Angeles, says that the brain cancer (malignant glioma) that killed O. J. Simpson's attorney, Johnnie Cochran, was the result of frequent cell phone use, based on the fact that the tumor developed on the side of the head against which he held his phone.

Initially used to protect against side - effects such as fractures, there is also some evidence that taking the drug extends the lives of women with breast cancer.

The guidance paper, jointly published this month in ACOEM's Journal of Occupational and Environmental Medicine (JOEM) and AAOHN's journal Workplace Health & Safety, summarizes current evidence regarding marijuana consumption; discusses possible side effects, including temporary impairment as it relates to the workplace; reviews existing federal and state laws that impact employers; and suggests various strategies available for monitoring marijuana use among employees.

He pointed out that the best evidence on both sides of the debate comes from digitizing maps from PowerPoint slides, none of which were intended to be used in this way.

«Limited data on medical cannabis use in children: Strongest evidence supports use to reduce seizures, side effects of chemotherapy.»

His current research seeks to document how people on either side of the controversy collect and use evidence about the claim that GMOs increase crop yields.

The objectives of the guidelines for the rational and responsible use of antimicrobials are: - Optimal outcome for male and female patients - Optimal use of antibiotics (range, mode of administration, dose, duration)- Minimizing side effects, such as adverse effects, development of resistance, nosocomial infections, C. difficile infections and costs The basics of the guidelines are evidence, international and national guidelines, the epidemiology of antimicrobial resistance at the USZ and the ex-factory prices of drugs.

Regardless of the type of legal proceeding or which side uses scientific evidence, the forensic scientist must be able to write a report and testify under oath about: what facts or items of evidence were analyzed or tested; what tests or analyses were used; how valid or reliable those tests or analyses have been found to be by other courts; why and how the forensic scientist was qualified to conduct those tests or analyses; and, what the results of the tests or analyses were and how those results are relevant to the issues in dispute.

Phase I Trials initial studies to determine the safety and pharmacologic actions of drugs in humans, and the side effects associated with increasing doses; in some cases can also be used to gain early evidence of effectiveness.

I really would love to hear your side of this and any evidence for the use of smoothies.

It details the practical uses of these herbs, the evidence behind them, a description of the plant, how to take it, and possible interactions and side effects.

I also hike a bit and do the occasional 5 - 10 mile run (used to be a cross-country runner — now I err on the side of less is more considering emerging evidence on endurance training and heart damage).

Despite the high use of sleep medication, increasing evidence has demonstrated that long - term use of such drugs may have negative side - effects including dependency, day - time drowsiness, nausea, fatigue, confusion, and memory problems (Ramar & Olsen, 2013).

To help fill the gaps for participants, sessions included exploring what leadership really means, understanding the process of policy analysis, figuring out how to get others to see all sides of an issue, figuring out how to effectively use research - based evidence, strategizing how to get quality teaching even without resources, and learning how to use the media to communicate a vision.

The teachers on the left side of the bell curve (see below) were more accurately identified this year, and the teachers on the «right» side became more effective due to the new and improved teacher evaluation system constructed by the state... and what might be renamed the Hogwarts Department of Education, led by Hanna Skandera — the state's Voldemort — who, in this article pointed out that these results evidence (and I use that term loosely) «that the system is doing a better job of pointing out good teachers.»

The sell - side in these types of situations tends to value companies at peak multiples of trough earnings, and only shifts to the more mid-cycle earnings and valuation we use when there's clear evidence the cycle has turned.

There is evidence that pancreatic secretions are suppressed during an attack of pancreatitis, so food delivered in this manner stimulates the pancreas less than we used to believe, while it helps maintain the health of the gastrointestinal tract and decrease inflammation and adverse side effects.

There is very weak veterinary clinical and experimental evidence based upon a limited number of studies to indicate that adding transdermal nitroglycerine to other therapies used for management of left - sided congestive heart failure in dogs speeds the resolution of clinical signs.

There is evidence that pancreatic secretions are suppressed during an attack of pancreatitis, so food delivered in this manner stimulates the pancreas less than we used to believe, and helps to maintain the health of the gastrointestinal tract and decrease inflammation and side effects such as those listed above.

When patients have evidence of these fluid accumulations as a result of right - sided heart disease, the term right - sided congestive heart failure (CHF) is used.

The side scan sonar equipment used to image the bottom of the Gulf may have been faulty, and the claimed supporting evidence is purely circumstantial.

On the other side of the Arctic, Russian martime operations using icebreakers on the Northern Sea Route began in 1932 and give no evidence for improving ice conditions in this period; rather the opposite, as 1937 and 1940 were noted for heavy ice in the Laptev Sea.

Until two years ago I used to teach both sides of the climate change debate and invite students to discuss the issue and reach their own conclusions based on the evidence available, I have now been stopped from doing this — apparently it confuses the students.

«The growing use of bottled water is evidence that the old ways of managing water challenges are putting us on the wrong side of history.

Let's also hear from loonies of the precautionary environmentalist side — the ones who had quite enough evidence in 1990 that AGW was a problem and would likely lead to many problems including increased storms (heat energy could become kinetic energy, they reasoned), so let's start turning off lights not in use & a myriad of other measures that not only save the earth but save us money.

As Mashey documents here, so well, this whole party has been a set - up, with scientists on one side, bound by the rules of evidence and by their own integrity, and think tanks, PR counsellors and their aides and allies on the other side, using any technique aailable (including, apparently, obtaining, using and disseminating stolen emails), to defend the right of fossil fuel companies to continue, unrestrained, in the sale and distribution of a substance that is threatening the human habitability of planet earth.

The question is the intent of the parties, and the court can look at all relevant evidence to decide whether both sides really meant to use e-signatures to accept the contract.

The Obama administration in 2015 tasked PCAST (President's Council of Advisors on Science and Technology) to advise «whether there are additional steps on the scientific side, beyond those already taken by the Administration in the aftermath of the highly critical 2009 National Research Council report on the state of the forensic sciences, that could help ensure the validity of forensic evidence used in the Nation's legal system.»

In Georgia, Motions in Limine can be filed as late as the morning of trial and they are aimed at preventing the other side from using improper arguments or introducing irrelevant evidence during the trial.

On the one hand, the court sent a clear direction to trial judges that they must take a more robust role as the gatekeeper of expert evidence, which should mark the end of either side using «hired guns.»

But what kind of driving evidence and signs of impairment are the police going to have for someone they suspect would blow.05 to warrant the use of the road side device?

There are BCCA decisions which suggest that where the parties have lead expert evidence on the issue of factual causation — certainly where both sides do, perhaps even where just one side «leads» the evidence, the robust and pragmatic approach can not be used.

My greatest concern is that I may never end up on the winning side of this fight because my narcissistic spouse has initiated the split after collecting «evidence» to use against me in what can only be referred to as an ambush.

US research published in Antimicrobial Agents and Chemotherapy indicated use of antibiotics was prevalent among terminally ill patients in hospice care arrangements — despite their unwanted side effects and little evidence that the medications improved symptoms or quality of life for these patients.