What I'm saying is that the strictly linear MATHEMATICAL operation of integration — continuous or discrete — can not produce
signal components at frequencies other than those already present in the signal.
The fitness of the human Burkitt lymphoma cell line Ramos requires the expression of the BCR
signaling component Igβ and the co ‐ receptor CD19.
Scaffold proteins offer a simple, flexible strategy for regulating selectivity in pathways, shaping output behaviors, and achieving new responses from
preexisting signaling components.
CITATION: «De Novo Transcriptomics Reveal Distinct
Phototransduction Signaling Components in the Retina and Skin of a Color - Changing Vertebrate, the Hogfish (Lachnolaimus Maximus),» Lorian E. Schweikert, Robert R. Fitak and Sönke Johnsen.
The presence of these molecules in choanoflagellates suggests that
signaling components needed to communicate between cells is evolutionarily ancient.
Reverse transcriptase - polymerase chain reaction (RT - PCT) analysis of synthetic sensing and
signaling components confirms expression of components of the sensing gene circuit.
While homology - based approaches are likely to be reliable for well - conserved pathways such as the
core signaling components of the innate immune network, it is difficult to confidently assign function to the numerous proteases, protease inhibitors, and similarly diverse gene families in the absence of direct functional information.
When the TOR pathway was blocked in the fat body by the overexpression of
signaling components TSC1 / 2, CCHa2 expression was significantly reduced (Fig 1J).
I am currently working with Zika virus and how it affects the T cell response and T cell signaling through tumor necrosis receptor (TNFR)
signaling components OX40, 4 - 1BB, and CD27 in specific mouse model systems.
Recent studies have shown that Act1 is also a key
positive signaling component for the IL - 17 signaling pathway, critical for TH17 - mediated autoimmune and inflammatory responses.
We primarily use structural and biochemical approaches to study the relevant interactions between CAF - 1 and the replisome and to investigate their interplay with S phase and
checkpoint signaling components.
Both DAG and calcium are essential second messengers which activate
downstream signaling components such as protein kinase C and calmodulin dependent kinase.
Characterization of one of the targets of this translation regulatory machinery, the
ethylene signaling component EBF2, indicates that the signaling molecule EIN2 and the nonsensemediated decay proteins UPFs play a central role in this ethylene - induced translational response.
The B ‐ cell antigen receptor (BCR)
signaling component Igβ (CD79b) and the co ‐ receptor CD19 act as an alternative B ‐ cell signaling module that promotes the survival of B lymphoma and normal B cells via integrated ITAM / PI3K signaling.
Table 1: Trends in °C / decade of
the signal components due to MEI, AOD and TSI in the regression of global temperature, for each of the five temperature records from 1979 to 2010.
The MAPK cascades:
signaling components, nuclear roles and mechanisms of nuclear translocation
By establishing this model in animals deficient in TLR2 or TLR2 -
signaling components, the team will for the first time discover if this immune pathway plays a role in the progression of these AMD - like lesions.
Table 1: Trends in °C / decade of
the signal components due to MEI, AOD and TSI in the regression of global temperature, for each of the five temperature records from 1979 to 2010.
We use observed estimates of
the signal component of TLT changes and model estimates of climate noise to calculate timescale - dependent signal - to - noise ratios (S / N).