Sentences with phrase «signal sequences in»

Not exact matches

After all, in a calculator, the pressing of «2» followed by «+» followed by «3» followed by «=» leads to a sequence of purely material (electronic) events that produce a final electronic signal to display the number 5.

«Such losses are particularly critical in the auditory system, because they reduce the temporal precision of signal transmission — and the quality of our perception of the acoustic environment is primarily dependent on rates of action potential generation and precise neural computation of their temporal sequences.»

The sequence is read by quantitative PCR, so that the signal is proportional to the protein concentration in the sample.

But to coax them down a specific path in the lab requires recreating the precise sequence and timing of environmental cues in the womb — the signals from proteins and hormones that tell cells what kind of tissue to become.

While the latter has a reputation for being hard to isolate, she explains that even degraded RNA generally contains enough intact sequence to analyze — provided investigators can detect the scarce tumor signals against the immense background of other RNA molecules in a sample.

When researchers sequenced the sponge's genome in 2010, they found genes that help individual cells cooperate as a group: how to divide, send signals to one another, and distinguish between friends and outsiders.

A second, well - understood form of epigenetic signaling, called DNA methylation, involves the addition of a methyl group — a carbon atom plus three hydrogen atoms — to particular bases in the DNA sequence.

In order for newly - produced secretory or membrane proteins to find their final destination, the proteins have signal - sequences connected to themselves as a form of address tag.

Detail of a crystal structure of unbound (right) and signal - sequence bound SRP forms (left, signal sequence depicted in red).

Researchers at Umeå University show in a new, detailed structural study, published in the journal Nature Communications, how the binding of the signal - sequence triggers a number of structural changes within the SRP particle.

Individual antennas in system transmit, in sequence, a weak microwave signals through the brain, while the other receiving antennas measure the reflected signals.

Previous studies identified three sub-events at intervals of 20 seconds in the seismic signals recorded during the 1980 Irpinia earthquake sequence, whose shared ground motion caused more than 3000 deaths and significant damage to structures.

Special heart cells create electrical signals that cause the heart's upper and lower chambers to beat in the proper sequence to pump blood through the body.

The lizard's signalling was reconstructed by digitising the position of multiple body parts through the sequence, subsequently combining the data from the two camera views to reconstruct the signalling motion in 3D, Ms Bian said.

In order to combine biologic components in any desired sequence signal converters must be connected between theIn order to combine biologic components in any desired sequence signal converters must be connected between thein any desired sequence signal converters must be connected between them.

The scientists then subtracted the EEG signals taken in response to a face sequence from those of a pattern - only sequence to extract the unique signature associated with the face stimulus and tracked how this electric signal evolved over time.

«The computational approach allows us to model, right down to the atomic level, how small changes in protein sequence can have a major impact on signaling,» said MacDermaid, assistant professor of research at Temple's Institute for Computational Molecular Science.

In many sequences, the normally continuous code for translating the DNA sequence into protein had been disrupted by a stop - codon, a signal to end translation.

For Virginia Postrel, writing in The Atlantic back in 2007, it was dramas like CSI and Numb3rs that were making braininess sexy and imparting a «geeky glamour» to the airwaves — and that was before the rise - to - total - dominance of House, a prime - time juggernaut whose climax each week involves a man having a scientific epiphany illustrated by an animated sequence of a corpuscle misinterpreting a hormonal signal from a gland.

The final component in this long series of signal sequences is the Yorkie effector protein that is the decisive factor at the end of the Hippo signaling pathway and determines the start of reactivation, growth, and division in the stem cells.

In the absence of an external signal, only the recording plasmid is active, and the cell adds copies of a spacer sequence to the CRISPR locus in its genomIn the absence of an external signal, only the recording plasmid is active, and the cell adds copies of a spacer sequence to the CRISPR locus in its genomin its genome.

As a result, they observed an interesting pattern — that the same components could both turn on and off some of the steps in the sequence — a phenomenon called paradoxical signaling.

«It's clear we lost the signal from the lander, but we don't know where it happened in the sequence of events,» Ferri says.

The image portrays a summery Finnish landscape in which the forest has been replaced by polymerase transcription signal (global run on sequencing = GRO - Seq).

Small organic sensor molecules were prepared that bind and signal the presence of unlabeled tripeptides in a sequence - selective manner.

Like many biological processes, it involves an entire sequence of molecular signals that result in the formation of new cells and tissue.

In most cells, the three - base sequence uracil - adenine - guanine is a stop signal that shuts down protein production.

To the other jug she added two enzymes that targeted the sequence that signaled the presence of a knight in the two threatened positions.

But in front of it was a termination sequence, flanked by two snippets that signaled the DNA recombinase.

Whatever their limitations, the two reports signal the dawn of a new era in genome sequencing and detecting changes in individual genomes.

Toll - like receptor 9 signaling activates NF - κB through IFN regulatory factor - 8 / IFN consensus sequence binding protein in dendritic cells.

Salt is involved in the last step in many signaling sequences and causes real cell membranes to thicken up.

Shannon entropy analysis of the NS5 polymerase mature protein revealed that a G374E mutation, in a region that contributes to interferon resistance in other flaviviruses by interfering with JAK - STAT signaling was present in both the Asian and American sequences from the 2007 - 2008 Venezuelan outbreak, but was absent in the sequences from the 2001 Venezuelan outbreak.

Transient assays were done in onion epidermal cells using the plant signal sequence fused to RBP and a GFP reporter (ssRBP - GFP fusion protein) with RBP fused to GFP as a control.

The group of researchers will work on further developing a highly integrated and parallel format with improved equipment for detection of the chemiluminescent signals resulting in a portable and inexpensive device for low - cost genome sequencing.

Our discovery that this conservation also extends to the level of HK transmembrane signaling allowed us to design a test system, whereby transmembrane fusions can be rapidly developed and tested in bacteria and then, with the addition of proper targeting sequences, function in plants.

While the Arabidopsis sequence may speed up plant science in general, the new MPK4 study will play into the hands of researchers interested in map kinase signaling, says Giraudat.

Jin found that types of neurons damaged in Parkinson's disease and Huntington's disease can broadcast the signals for starting or stopping newly learned action sequences.

Prior to the new study, scientists thought that the machinery in a cell created signalling peptides by cutting fragments out of proteins in sequence, and displaying these in order on the surface of the cell.

They also investigate how these interactions change in melanocytes depending on a combination of factors, including an individual's unique DNA sequence, DNA mutations that arise in a cell over time or due to environmental exposure, and the signals that are present in a cell's surrounding micro-environment.

After we have calculated the S indices for the 5,648 main - sequence stars based on the LAMOST spectra with signal - to - noise ratios higher than 10 in the blue part of the spectrum, including the subset of 48 superflare stars, it is possible to calculate the flare rates.

Gene ontology (GO) analysis of genes within 250 kb of a PORE sequence revealed enrichment in processes such as transcription regulator activity (p < 0.001), sex determination (p < 0.005), insulin receptor signaling (p < 0.001), development (p < 0.0005), and protein phosphorylation (p < 0.005).

Peptide quantification is facilitated by associating signal intensities in features with peptide sequences derived from MS2 spectra.

Although the reasons why Plasmodium proteins are difficult to express in heterologous expression systems are not clear, several protein characteristics, such as high molecular mass (> 60 kDa), presence of export motifs, and atypical signal peptide sequences negatively impact recombinant expression [12].

In nanopore sequencing devices, electrolytic current signals are sensitive to base modifications, such as 5 - methylcytosine (5 - mC).

Specifically, we have generated clusters of transcripts that behave the same way under the entire spectrum of the sixty - seven experimental conditions; we have assembled genes in groups according to their time of expression during successive days of ES cell differentiation; we have included expression profiles of specific gene classes such as transcription regulatory factors and Expressed Sequence Tags; transcripts have been arranged in «Expression Waves» and juxtaposed to genes with opposite or complementary expression patterns; we have designed search engines to display the expression profile of any transcript during ES cell differentiation; gene expression data have been organized in animated graphs of KEGG signaling and metabolic pathways; and finally, we have incorporated advanced functional annotations for individual genes or gene clusters of interest and links to microarray and genomic resources.

Consequently, the contrast between sequences with two levels of embedding against one also reflects manipulation — on top of encoding and maintenance — of the incoming acoustic signals in tonal working memory.

In experimental and prototype nanopore sequencing devices it has been shown that the electrolytic current signals are sensitive to base modifications, such as 5 - methylcytosine.

The sequence 888 is a signal to stay open to abundance in whatever form it appears, not just the forms we expect or have become attached to.

There's a striking, gutsy credibility about it all, which makes up for its dramatic flaws, such as the sequence in which Julian and Yanelly signal at each other in public while a guard benignly and implausibly looks on.