Sentences with phrase «signal transduction mechanisms»

We discovered several Eph receptors and ephrins, and research in our laboratory is dedicated to the characterization of Eph receptor signal transduction mechanisms and biological functions using biochemical, mass spectrometry, molecular biology and cell biology approaches in conjunction with animal models.

We have identified three classes of signal transduction mechanisms that may be mediated or modulated by NG2.

The signal transduction mechanisms of Eph receptors are intriguing, and complex, because these receptors engage in multiple modes of signaling.

Klemke, Wang, and their colleagues are involved in research on aspects of the basic biology behind metastasis — trying to identify the signal transduction mechanisms that lead to the spread of breast cancer cells.

Intra - and intermolecular signal transduction mechanisms in membrane - embedded (photo --RRB- receptor / transducer complexes are studied using the photoreceptor / transducer complex NpSRII / NpHtrII, which is responsible for the photoactive behavior of the halophilic archaeon Natronomonas pharaonis.

Furthermore, the hedgehog pathway, a reactivated embryonic pathway in cancer cells, was reported as pyrvinium - sensitive signal transduction mechanism [65].

Not exact matches

It is expected that the molecular mechanisms underlying the inhibition of interferon signal transduction by C proteins would then be fully identified.

They regulate signal transduction and indirectly control plant defense mechanisms.

The actin cytoskeleton mediates these responses, but the signal transduction pathway leading to chloroplast movement and the mechanism of chloroplast motility is not entirely understood.

Given the predominant role for DAG on regulating Ras / Erk and PKC - θ signaling and Cbl - b for regulating PI (3) K signaling, we hypothesized that T cells deficient in DGKζ or Cbl - b would alter TCR signal transduction through distinct mechanisms, such that DGKζ - deficient T cells would demonstrate strongly enhanced Ras / ERK activation, but only modestly enhanced NF - κB activation, and Cbl - b — deficient T cells would demonstrate modestly enhanced Ras / ERK activation and strongly enhanced NF - κB activation.

Molecular mechanisms of heart failure and arrhythmogenesis with focus on signal transduction

Understanding the underlying mechanisms allows identifying putative sites for pharmacological intervention and opens the prospect of engineering artificial molecular switches derived from the highly efficient systems that have evolved for cellular signal transduction.

Helicobacter pylori effector protein CagA activates the signal transduction and activator of transcription 3 (STAT3) signaling pathway: a potential mechanism for gastric cancer development.

Symposia III: Mechanisms of Baro and Chemoreceptor Sensory Transduction: A Link to Sympatho - excitation in Disease Researchers will discuss how sensory neuronal signals are powerful regulators of the hypertensive state and the role of gaseous messengers in oxygen Sensing by the carotid body.

The Neurophysics Group has the objective to study physical mechanisms underlying signal perception and transduction in the nervous system and to apply experimental physics methods to problems in neuroscience.

One mechanism could be to differentially regulate the molecular components involved in cue detection, such as ORs or VRs [20] or in known elements of their signal transduction pathways, under the control of sex - specific hormones.