Sentences with phrase «signaling by another molecule»

Signaling by molecules called prostaglandins plays a key role in the body's response to inflammation.

Not exact matches

The researchers interpret this to mean that it is being spread by larger molecules, most likely special signaling proteins, that diffuse more slowly than ions.

The researchers looked for 200 types of immune - signaling molecules called cytokines and identified 64 that were different, usually more abundant, in the eyes affected by NIV.

The protein expressed by the gene is thought to bind to serotonin receptor molecules and ferry them to the cell surface, positioning them to receive serotonin's signals from neighboring cells.

Now, the «smart» bandage developed by the team provides direct, noninvasive measurement of tissue oxygenation by combining three simple, compact and inexpensive components: a bright sensor molecule with a long phosphorescence lifetime and appropriate dynamic range; a bandage material compatible with the sensor molecule that conforms to the skin's surface to form an airtight seal; and an imaging device capable of capturing the oxygen - dependent signals from the bandage with high signal - to - noise ratio.

When they react to external stimuli, by binding molecules, for example, a structural transformation takes place on the inside that triggers a signalling cascade (see 2012 Nobel Prize in Chemistry).

A study in this issue of JCI Insight demonstrates that mice lacking the proinflammatory signaling molecule TAK1 are protected from obesity and insulin resistance induced by a high fat diet.

Gene expression is the process where information stored as DNA is converted (transcribed) by enzymes into related molecules called RNAs, and then into proteins that make up the body's structures and signals.

Using small - molecule inhibitors to eliminate the activity of the proteins produced by the bird - specific, median signaling zone in chicken embryos, the researchers were able to induce the ancestral molecular activity and the ancestral anatomy.

In bird eyes, suitable radicals are believed to be generated within cryptochrome, a light - absorbing protein that produces an as - yet - unidentified signaling molecule in a quantity determined by the field direction, resulting in an avian magnetic compass.

«That upheld our hypothesis, which was that biochar could interfere with cell signaling, most likely by binding with the fatty - acid molecules that the speakers were using to broadcast their message.»

Loss of LKB1 by regulatory T cells was also associated with increased levels of signaling molecules or cytokines associated with the Th2 immune response, Kai said.

Brassinosteroids and auxins are two growth promoting plant hormones and the study goes further in showing that their signalling molecules were also stimulated by biochar application.

The team concludes that these signals are generated by speeding electrons produced when cosmic rays collide with molecules in the air (Physical Review Letters, DOI: 10.1103 / PhysRevLett.105.151101).

In what Grashorn calls a «serendipitous discovery», his team has worked out that these signals are generated by speeding electrons produced when cosmic rays collide with molecules in the air.

If indole allows pathogenic bacteria to withstand antibiotics, it may be possible to thwart drug resistance by blocking indole signaling with small molecules, Collins says.

This seems to be triggered by the collective release of a signalling molecule called interferon - beta, although what causes this is unclear.

«We found that AIM2 inhibits tumorigenesis in multiple animal models of colorectal cancer by restricting the pro-survival signaling molecule, Akt, which is commonly hyperactive in many human cancers.»

And it's essential to understand how neurobiological processing conducted by molecules and cells and electrical signaling gets translated into behaviors, from simple bodily movements to complex social interactions.

The molecule appears to be a potent signal broadcast by an immune system under siege.

Cell biologists would like to reduce the complex communication patterns traced by molecules that regulate the health of the cell to a set of signaling rules.

In a study published in the journal Nature Medicine, the researchers reported that the tumor - suppressing protein AIM2, or Absent in Melanoma 2, helps prevent colon cancer by restricting a signaling molecule called Akt.

The ER / PR receptors also have no known direct connection to the signaling molecules activated by MC1R.

Frey and his colleagues made use of mathematical models to analyze the complex interplay between ecological factors and population dynamics, and were able to demonstrate that populations can indeed respond in a coordinated fashion to chemical information even when the signal molecules are generated by only a subset of the cells.

Cytokines can reach the brain several ways: directly through the blood - brain barrier or indirectly by binding to nerve fibers elsewhere, which send signals to the brain to produce the inflammation molecules.

Whereas Mary Wang» ombe focuses on the receptor protein and its function, Badou Mendy concentrates on isolating the signal molecule released by the nematodes.

Estrogen molecules caught by the longer aptamer are likely held above the bilayer, and so do not create the electrical signal.

«By tweaking the dormant state of the molecule, we can get myostatin to signal without the need for cutting, basically picking the lock without a key.

By scanning through the sample, plane after plane, researchers can gather the fluorescence signals emitted from molecule - bound dyes over the entire depth.

Therefore, by measuring the atoms» neutron scattering signals, the team was able to discern the movement of tRNA in water, providing valuable insight into how the large molecule relaxes in different environmental conditions.

By interaction with externally docking ligand molecules, external signals are transmitted into the cell.

It was originally investigated in 1995 by pharmacologist Franco Borsini and a team of researchers at Boehringer Ingelheim Italia in Milan as an antidepressant because of its ability to regulate neurotransmitters — the brain's chemical - signaling molecules.

Bacterial cells communicate with one another by using chemical signal molecules, which they synthesize and secrete into their surroundings.

As target depth increases, the single - scattered signal (red) becomes negligibly small, because it is more likely that the waves will get bounced around by other biological molecules in their path (blue).

Unbalanced signaling by two molecules that regulate breathing leads to sleep apnea in mice and rats, researchers report in the Jan. 23, 2017, Proceedings of the National Academy of Sciences.

Advances in understanding the cells and molecules that transmit pain signals are providing new targets for drugs that could relieve various kinds of pain — including those poorly controlled by existing therapies

By using pharmacological small molecule inhibitors as well as neutrophils from genetically modified mouse strains the team could identify essential receptor and signaling pathways involved in the nicotine - mediated activation of neutrophils.

Gleevec incapacitates the enzyme by docking into a pocket on the enzyme's surface that is usually reserved for a signaling molecule known as ATP.

«Recent work by other groups has shown that bile acids act as signalling molecules in the host, almost like a hormonal network, with an ability to influence host metabolism.

Remarkably, giving animals injections of lithium salts — which mimics WNT signaling by inhibiting the molecule GSK3 — or giving animals a more specific GSK inhibitor, the researchers were able to restore normal synapse and spine numbers and also improve some of the most significant psychiatric - like behavioral abnormalities in these mice.

But in the mid-1980s, three U.S. investigators discovered that it is a signal - transmitting molecule naturally used by the pulmonary, cardiac and other systems, a discovery that received the 1998 Nobel Prize.

I ache to see your action potential in action To be blinded by the searing speed of your electric signal As it sparks from node to node To behold the violent beauty of vesicles fusing with your presynaptic membrane — Pouring their contents into your synaptic cleft How I wish to be your postsynaptic cell So that I may be flooded by your molecules

Using radio telescopes in Spain, France, and Australia, a team headed by researchers from the Max Planck Institute for Radio Astronomy in Bonn, Germany, scanned the LMH for signals in the precise wavelengths that would reveal the presence of more complex molecules.

They found these molecules not with optical telescopes but by tuning in with exquisitely sensitive antenna dishes that can receive the extremely faint radio signals generated by molecular clouds.

Jirtle says the nutrients probably help by providing a ready supply of methyl molecules, which act as stop signals at key places in the genome.

A chemical interaction with target molecules subtly alters the magnetic signal from the xenon; by detecting this change researchers can identify the molecules in a complex mixture.

When a low - energy neutrino or antineutrino from a supernova collides with a water molecule in the tank, the resulting light signal is recorded by about 100 of 13,000 photomultipliers, ultrasensitive light - detecting devices that turn a tiny flash of light into a larger recordable burst of electricity.

An Israeli - led team has found that some of the receptor molecules carried by our cells can cause them to self - destruct, even if they are not triggered to do so by an external signal.

The team at Barts Cancer Institute, part of Queen Mary University of London, have found that a molecule, called focal adhesion kinase (FAK), signals the body to repair itself after chemotherapy or radiotherapy, which kill cancer cells by damaging DNA.

Now, an international group led by Prof. Danny Porath of the Hebrew University of Jerusalem reports reproducible and quantitative measurements of electricity flow through long molecules made of four DNA strands, signaling a significant breakthrough towards the development of DNA - based electrical circuits.