Our laboratory has spent many years delineating the regulation of translation initiation by the mTORC1 and ERK
signaling cascades during LTP, LTD, and memory formation in the hippocampus.
In subsequent experiments, the Einstein team deciphered other parts of the Rac1
signaling cascade during invasion and showed that this signaling mechanism is regulated differently in normal breast epithelial cells.
Not exact matches
Detailed biochemical and sophisticated imaging experiments are employed to delineate the molecular
signaling cascades that couple receptors to the translational apparatus
during long - lasting synaptic plasticity in the hippocampus, amygdala, cortex, and striatum, and whether these types of translational control are required for memory formation, social behaviors, and behavioral flexibility.
8.30 Hana Paculová CDK12 connects transcriptional regulation to DNA damage repair pathway 8.55 Karol Kaiser Wnt secretion
during nervous system development 9.20 Simona Hankeová The role of Notch
signaling in vasculogenesis 10.00 Coffee break 10.30 Tomáš Doležal Extracellular adenosine regulates complex host - pathogen interactions through the energy release for the immune response 10.55 Ondřej Bernatík and Igor Červenka Regulation of diverse function of Dvl by phosphorylation 11.20 Jan Ryneš Dissection of Axin interactome: rational approach for control of
signaling cascades via intervention with specific protein - protein interactions 12.05 Targeting opportunities: discussion & sum - up 13.00 Lunch and departure
Melanocytes have the capacity to respond to a diverse number of extracellular
signals, including UVR, endocrine
signaling cascades that occur
during pregnancy, micro-environments of the stem cell hair bulge vs. differentiated hair follicle niches, and hypoxic conditions found in metastatic melanoma tumors.
In the Lu laboratory, we aim to elucidate the
signaling cascades that establish neural circuit connections
during brain development, to understand how sensory experiences and environmental factors affect neural circuit wiring and cognitive behaviors, and to identify novel factors required to maintain the health of neural circuits
during aging.
Her research focuses on the
signaling cascades underlying neural circuit connections
during brain development, to understand how sensory experiences affect neural circuit wiring, and to identify novel factors required to maintain the health of neural circuits
during aging.