Sentences with phrase «signaling cascades involved»

Multiple compounds with the Super DMZ 5.0 formula have been clinically demonstrated to activate / inhibit key signaling cascades involved in the regulation of blood glucose, glycogen synthesis, fatty acid synthesis, transcriptional regulation, and cytokine - mediated inflammation.

We are currently investigating the details of the signaling cascades involved in these phenomena, as well as attempting to identify cytoplasmic binding partners for NG2 which may serve as effector molecules for activation of downstream signaling events.

Not exact matches

Bohn noted isoquinolinone 2.1 is one example of a new class of «biased» kappa agonists that avoid many central nervous system side effects by preferentially activating a G protein - mediated signaling cascade without involving another system based on β - arrestin protein interactions.

Moreover; in addition to the various mutations that have been highlighted and interact in key component of signaling cascades, different types of RNAs have been shown to be involved in melanoma pathogenesis such as: miRNAs and lncRNAs [48, 49].

Inhibition of signaling pathways, especially of the Wnt / β - catenin and hedgehog transduction cascades are newly described modalities involved in antitumor activity of the anthelminthics.

Now, this is actually a relatively simplified form of this cascade, and every day we're learning more about other factors that are involved in insulin signaling.

The epidermal growth factor receptor (EGFR) pathway is a complex signaling cascade that is involved in the development and progression of cancer.

Activation of the insulin receptor involves its autophosphorylation, which is followed by phosphorylation of several target proteins in the signaling cascade.