Sentences with phrase «signaling factor in»

«The mineral zinc acts as a catalytic, structural and signaling factor in the regulation of a diverse array of cellular pathways involving hundreds of enzymes and proteins,» he said.
Fiona Doetsch's group uncovered that the choroid plexus secretes a wide variety of important signaling factors in the CSF, which are important for stem cell regulation throughout life.

Not exact matches

In 2007, we had 12.5 factors sending warning signals.
The fifth, and most recent, factor is the US Federal Reserve's signals that it might end its policy of quantitative easing earlier than expected, and its hints of an eventual exit from zero interest rates, both of which have caused turbulence in emerging economies» financial markets.
Moreover, Google's algorithm considers social signals as one of its most important ranking factors — socially shared content is a vote of approval, or at the very least importance, so it makes sense Google would consider it when deciding whether a post should rank well in organic search.
Signals of trust, merit, and intent of source can be determined in a couple ways... with an algorithm that looks at on - site or off - site signals, or without an algorithm at all, using offline factors (rarely discussedSignals of trust, merit, and intent of source can be determined in a couple ways... with an algorithm that looks at on - site or off - site signals, or without an algorithm at all, using offline factors (rarely discussedsignals, or without an algorithm at all, using offline factors (rarely discussed, BTW).
Social signals are becoming a bigger factor in the organic search ranking algorithm each day.
For Target, the investment signals a move to put its money where its mouth is in its attempt to reclaim some of the cool factor that made it a hit among discount retailers for so long through relationships with popular designers and brands.
These two factors signal to us that the Euro is likely to go higher, the US dollar lower and gold priced in dollars to increase.
After adjusting for seasonal factors, the headline Markit / JMMA Purchasing Managers» Index ™ (PMI ™) posted 47.7 in August, down from 47.9 one month previously, signalling the sharpest worsening of Japanese manufacturing sector operating conditions since April 2011.
The uneventful April FOMC expectedly left the door open for a possible rate hike in June without committing the Federal Reserve for policy action, and policymakers also signaled easing concerns over foreign risk factors.
The Ninth Circuit took a similar approach in Berson v. Applied Signal Technology, Inc., and ultimately fashioned a standard for loss causation in Nuveen v. City of Alameda when it held that a plaintiff can establish loss causation «by showing that the defendant misrepresented or omitted the very facts that were a substantial factor in causing the plaintiff's economic loss.»
So what are the factors the could signal a recover in natural gas prices?
There is significant edge in how factor signals are constructed.
It uses a complex algorithm to factor everything in and then looks for key signals that tell it to place a trade.
Another important thing that Whitehead was onto is that we do not in non-laboratory conditions start from a single factor, like an intensity meter, and react by signaling the presence of the factor by a sensation.
Our age is a major factor in how our brains read, or misread, all those signals.
Vettel's recent 18 - race streak was a huge factor in his championship challenge last year, before the Singapore start crash signalled the beginning of the end of his title hopes.
In a study that was done in 2001, titled Factors associated with Toilet Training in the 1990s done by Dr. R. Schum et al, AND another study done in 2003 titled Relationship between age at initiation of toilet training and duration of training: a prospective study by Blum NJ, Taubman B & Nemeth N show that while boys and girls often show readiness signals / behavior at similar ages, it has been shown that girls begin and complete potty training earlier than boyIn a study that was done in 2001, titled Factors associated with Toilet Training in the 1990s done by Dr. R. Schum et al, AND another study done in 2003 titled Relationship between age at initiation of toilet training and duration of training: a prospective study by Blum NJ, Taubman B & Nemeth N show that while boys and girls often show readiness signals / behavior at similar ages, it has been shown that girls begin and complete potty training earlier than boyin 2001, titled Factors associated with Toilet Training in the 1990s done by Dr. R. Schum et al, AND another study done in 2003 titled Relationship between age at initiation of toilet training and duration of training: a prospective study by Blum NJ, Taubman B & Nemeth N show that while boys and girls often show readiness signals / behavior at similar ages, it has been shown that girls begin and complete potty training earlier than boyin the 1990s done by Dr. R. Schum et al, AND another study done in 2003 titled Relationship between age at initiation of toilet training and duration of training: a prospective study by Blum NJ, Taubman B & Nemeth N show that while boys and girls often show readiness signals / behavior at similar ages, it has been shown that girls begin and complete potty training earlier than boyin 2003 titled Relationship between age at initiation of toilet training and duration of training: a prospective study by Blum NJ, Taubman B & Nemeth N show that while boys and girls often show readiness signals / behavior at similar ages, it has been shown that girls begin and complete potty training earlier than boys!
Signals are the most important factor of the training because without them, parents will not be successful in the training process.
Fetuses use vitamin D in the womb for many important processes including regulation of the metabolism of neurotropic factors and neurotoxins, signaling neuronal differentiation, and protecting the brain from inflammation.
Each factor involved in the tumor response — whether it is the speed with which chemotherapeutic drugs reach the tissue or the degree to which cells signal each other to grow — is characterized by a mathematical equation that captures its essence.
In complex wound management, we think a lot about what the signaling pathways are and what factors can be involved and what kind of things we could do to improve things.
A number of individual genes have been linked to suicide, such as those involved in the brain's response to mood - lifting serotonin, and a signalling molecule called brain - derived neurotrophic factor (BDNF), which regulates the brain's response to stress.
One factor keeping cells in this immature state is the PTEN gene, which suppresses a signalling pathway involved in cell growth.
In contrast, Loeys - Dietz is traced to a genetic defect in the TGF — beta (transforming growth factor — beta) signaling pathwaIn contrast, Loeys - Dietz is traced to a genetic defect in the TGF — beta (transforming growth factor — beta) signaling pathwain the TGF — beta (transforming growth factor — beta) signaling pathway.
They began snipping off the tip of a growing tail at one stage and stapling it, with fine tungsten wire, to a later stage, to see if the growth factors in action during early tail growth could override the stopping signals.
«Thus, we hypothesize that Gdf3 combines with Ndr1 and Ndr2 to facilitate Nodal signaling during zebrafish development, acting as an essential factor in embryonic patterning,» said Pelliccia, a graduate student in molecular biology.
In averaging out what is and is not a good candidate signal, she says, the study overlooks the factors that made Kepler 452 b so promising in the first placIn averaging out what is and is not a good candidate signal, she says, the study overlooks the factors that made Kepler 452 b so promising in the first placin the first place.
It seemed so obvious that if fairly small changes in development, which adjusted the timing and concentrations of growth and signaling factors, could have led to the evolution of birds from nonavian dinosaurs, we could readjust those changes in development and get a dinosaur from a chick embryo.
A study published in the journal PLOS ONE reports that the synthetic molecule JK - 31 blocks the signalling of a «growth factor» chemical that promotes the creation of networks of blood vessels to feed tumors.
Designed for use in spinal fusion surgery of the lower back, Infuse consists of a titanium cage that houses a collagen sponge soaked in bone morphogenetic protein (BMP), a growth factor that signals bone - forming cells to produce new tissue.
Suppression of signaling by insulin and the related hormone insulin - like growth factor - 1 (IGF - 1) extends life span in many species.
«CRKII most likely regulates the stability of mutated epidermal growth factor receptors and drives cancer growth by promoting signaling, or communication, within cancer cells,» said Julia Petschnigg, lead author on the paper and a postdoctoral fellow at U of T. «We found that a combinatorial chemotherapy that inhibits those mutated receptors and CRKII could be beneficial in treating lung cancer.»
The second gene, TNFRSF6B, encodes a receptor related to those that bind tumor necrosis factor (TNF)-- a key chemical signal for triggering inflammation in IBD as well as in patients with other autoimmune disorders such as rheumatoid arthritis and psoriasis.
In addition, using methods for the analysis of regulatory networks developed by the Califano lab in the Center for Computational Biology and Bioinformatics, Department of Systems Biology, the researchers identified a number of transcription factors (gene regulators) that have the potential to mimic the environmental signals that trigger papillae to induce new hair growtIn addition, using methods for the analysis of regulatory networks developed by the Califano lab in the Center for Computational Biology and Bioinformatics, Department of Systems Biology, the researchers identified a number of transcription factors (gene regulators) that have the potential to mimic the environmental signals that trigger papillae to induce new hair growtin the Center for Computational Biology and Bioinformatics, Department of Systems Biology, the researchers identified a number of transcription factors (gene regulators) that have the potential to mimic the environmental signals that trigger papillae to induce new hair growth.
About ten years ago, research results showed that things are not quite as simple as that: «Under most conditions, H2O2 is not an undesired side product but rather an essential chemical messenger that plays an important role in regulating the way in which body cells respond to signals from outside such as hormones and growth factors,» says Dr. Tobias Dick of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ).
The STAT3 protein - it stands for «signal transducer and activator of transcription 3» - is a suspected factor in the relapse of nearly 40 percent of children with AML.
In addition to its known roles in cancerous cells, STAT3 also is an essential mediator of cytokine and growth factor signals in normal cells that are important for diverse processes including immunity and inflammatioIn addition to its known roles in cancerous cells, STAT3 also is an essential mediator of cytokine and growth factor signals in normal cells that are important for diverse processes including immunity and inflammatioin cancerous cells, STAT3 also is an essential mediator of cytokine and growth factor signals in normal cells that are important for diverse processes including immunity and inflammatioin normal cells that are important for diverse processes including immunity and inflammation.
SU101 targets the signal transduction activated by a messenger called platelet - derived growth factor, which controls the genes involved in tissue formation and wound healing.
Since it is known that 13 different members of the fibroblast growth factor, or Fgf, family act as signaling proteins between the two different tissues — dental mesenchyme and oral epithelium — during murine tooth development, Javed and colleagues looked for changes in Fgf ligands in the mice lacking Sp7.
Frey and his colleagues made use of mathematical models to analyze the complex interplay between ecological factors and population dynamics, and were able to demonstrate that populations can indeed respond in a coordinated fashion to chemical information even when the signal molecules are generated by only a subset of the cells.
«This should signal that mental health is an important factor to consider in targeting outreach for binge drinking prevention and cessation programs.»
Her work described the regulatory link between the metabolic enzyme ATP - citrate lyase and histone acetylation levels in mammalian cells, and established that glucose utilization in the hexosamine biosynthetic pathway regulates growth factor receptor signaling.
Among the issues to be resolved there would be, for example, how to identify the environmental factors that control the production of aggressive morphs; what costs and benefits interaction involves for each participant; the taxonomic status of the deceit and the variability level in the chemical signal used for misleading ants; or what happens with related aphid species which also relate with ants.
These include a family of signaling molecules called protocaderins, which regulate neuronal development and short - range interactions between neurons, and a family of transcription factors called zinc fingers, which are mainly expressed in embryonic and nervous tissues and are thought to play roles in brain development.
Both the mice with modifications in BDNF signalling on top of Alzheimer's transgenes and the APP / PS1 mice treated with CDNF underwent an extensive behavioural test battery to measure neurotrophic factor effects on memory functions.
To unravel the complex signaling pathway map, the scientists used their own findings from the analysis of factors regulated up or down in the interplay between tissue and stem cells, linking them with the signaling pathways described in existing literature.
Once focused mainly on detecting radio signals from extraterrestrial civilizations, the institute now employs scientists studying many factors important for the existence of alien life — from Kepler team members who are detecting and characterizing exoplanetary systems, to astrobiologists searching for life in the most extreme environments on Earth and in the solar system's exotic nooks and crannies.
The team's findings paint a clear picture: in alert mode, the stem cells emit signaling substances, which in turn induce tissue cells to release the connective tissue growth factor (CTGF) messenger.
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