Sentences with phrase «signaling factors»

Here we used our knowledge of the developmental biology of many other animal models to provide the positive and negative signaling factors to guide the developmental choices of these tissue and organ stem cells.

Fiona Doetsch's group uncovered that the choroid plexus secretes a wide variety of important signaling factors in the CSF, which are important for stem cell regulation throughout life.

«The mineral zinc acts as a catalytic, structural and signaling factor in the regulation of a diverse array of cellular pathways involving hundreds of enzymes and proteins,» he said.

Moreover, small amounts of singlet oxygen produced during metabolic reactions can act as a local signaling factor that oxidizes and modifies target molecules, but the underlying mechanisms are poorly understood.

Jessell's work has revealed how gradual changes in the concentration of secreted signalling factors induce and steer the molecular switches that turn genes on and off to determine the identity of specific neuronal subtypes, as well as the precise positions in which they are generated.

His lab has also reported that a different signaling factor called phospholipase C - beta3 (PLC - β3) antagonizes mast cell activation by blocking STAT5.

The findings not only help explain how singlet oxygen functions, they introduce a method that can be used for further exploration of this important signaling factor.

We don't use the signal factor.

It seemed so obvious that if fairly small changes in development, which adjusted the timing and concentrations of growth and signaling factors, could have led to the evolution of birds from nonavian dinosaurs, we could readjust those changes in development and get a dinosaur from a chick embryo.

The enhancement of minis appears to provoke the postsynaptic neuron to release a signaling factor, still unidentified, that goes back to the presynaptic cell and activates an enzyme called PKA.

Using certain genes and signal factors, the team led by Prof. Dr. Thomas Holstein of the Centre for Organismal Studies demonstrated how the origin of nerve cell centralization can be traced back to the diffuse nerve net of simple and original lower animals like the sea anemone.

In the course of their research, however, the scientists discovered that the nerve net of the embryonic sea anemone is formed by a set of neuronal genes and signal factors that are also found in vertebrates.

In the future, the research team plans to investigate the composition of the signaling factors secreted by the choroid plexus, as well as how these change in different states and affect neural stem cells.

Specifically, the data reveal distinct transitions in factors that influence the different cellular states including cell cycle regulators, transcription factors, and signaling factors.

But any trading strategy that already uses share buybacks as a signaling factor might benefit from an augmentation that accounts for past buyback completion rate.