Forward - looking studies are examining other possible information couriers: glial cells (poorly understood brain cells that are 10 times as common as neurons), other kinds of
signaling mechanisms between cells (such as newly discovered gases and peptides), and the biochemical cascades that take place inside cells.
Not exact matches
These interactions suggest
mechanisms for communication
between distinct
signal - transducing pathways.
The
mechanism that allows individual Purkinje cells to differentiate
between the two kinds of climbing fiber
signals is an open question.
But that is probably not the only route through which neuregulin - 1 confers its benefits, and the group is exploring other possible
mechanisms — such as whether the protein improves
signaling between neurons, which is impaired in Alzheimer's — says the study's first author Jiqing Xu, a research associate in Lee's group.
This was found to interfere with the same
mechanism, essentially by impairing the ability of alpha - synuclein to regulate the flow of synaptic vesicles, and hence compromising the
signalling between neurons.
Among the behavioral responses elicited through olfactory
signals, many are clearly distinct
between adult male and female mice, including sexual conduct [3], [4], [6], aggressive responses to intruders [2], and parental care [16], but the
mechanisms that ensure such differentiated responses have not yet been fully elucidated in mammals [17].
Future experiments to validate this model by directly manipulating
signaling between conceptus and endometrium will allow for a more precise understanding of the
mechanisms of pregnancy failures that occur during the periimplantation period after normal fertilization and SCNT cloning.
The relationship
between FOXO1 and the sirtuins, both of which are inhibited by insulin receptor
signaling, may be the key
mechanism behind the life - extending effects of calorie restriction with adequate nutrition (CRAN).
Even the most eminent of them often show no capabilty of distinguishing
between coherent
signal transmission through a semitransparent atmosphere (a well - undersood problem) and diffusive transfer of thermal energy through all
mechanisms, including moist convection (a poorly understood problem).
Confidence in premises 1 - 6 is enhanced by the agreement
between the simulations and observations of the 20th century surface temperature and the distinct
signals produced by the various forcing
mechanisms.
Acceptance of the child's interests with responses that are prompt and contingent to what the child
signals supports learning, in part, by facilitating the child's development of
mechanisms for coping with stress and novelty in his or her environment.2 With repeated positive experiences, a trust and bond develop
between the child and parent that in turn allow the child to ultimately internalize this trust and then generalize their learning to new experiences.