Sentences with phrase «signaling proteins within»

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Within the framework of research projects of the German Center for Diabetes Research (DZD), scientists of the Research Unit Protein Science (PROT) and the Institute of Experimental Genetics (IEG) at Helmholtz Zentrum München (HMGU) have now investigated how drug treatment affects these signal carriers.
In bird eyes, suitable radicals are believed to be generated within cryptochrome, a light - absorbing protein that produces an as - yet - unidentified signaling molecule in a quantity determined by the field direction, resulting in an avian magnetic compass.
The Ras proteins are small GTPase enzymes that transmit signals within cells.
When attractant or repellant chemicals attach themselves to receptor sites on the surface membrane of a bacterium, it triggers a process within the cell that leads to the modification of the signal protein, CheY (pronounced «Key - Y»), enabling it to bind to the switch and change the bacteria's direction of movement.
In general, protein kinases are mainly responsible for the transmission of extra-cellular signals within cells.
Cell receptors will receive a signal from outside, and when it binds, that information is transmitted through the receptor to other proteins within the cell, [creating] a chain of events to change how the gene works in the cell.
They then conducted biochemical analyses to identify neuroligin - 3, confirm that the protein could stimulate tumor growth in cultured samples of several kinds of human high - grade gliomas and study which signals the protein uses within glioma cells to promote their growth.
These signals are passed within the cell from one protein to another and ensure cell growth and survival.
Characterization of a nuclear export signal within the human T cell leukemia virus type I transactivator protein Tax.
Optogenetics, a technology that allows scientists to control brain activity by shining light on neurons, relies on light - sensitive proteins that can suppress or stimulate electrical signals within cells.
Around 60 % of human colorectal cancers have mutations in the KRAS, BRAF or ERBB genes — all of which encode proteins coupled to the Ras pathway, a well - known way of transmitting signals within cells.
When Walter arrived in Blobel's lab as a fresh - faced apprentice, Blobel and his colleagues had limned the outlines of the so - called signal hypothesis, which purported to explain how proteins, which are made in cellular machines called ribosomes, find their pre-destined locations within cells.
They receive signals from outside the cell via partner receptors on the cell surface, and G - proteins help deliver those signals to their proper destinations within the cell.
There is also another mechanism by which cellular amino acid nutrition impacts on mTOR signalling; this involves the amino acids generated within the lysosomes by intracellular protein degradation and autophagosomal digestion [23,24].
Gene ontology (GO) analysis of genes within 250 kb of a PORE sequence revealed enrichment in processes such as transcription regulator activity (p < 0.001), sex determination (p < 0.005), insulin receptor signaling (p < 0.001), development (p < 0.0005), and protein phosphorylation (p < 0.005).
In a similar fashion, other tools assess whether mutations fall within annotated Pfam domains or signaling peptides of the encoded protein.
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