Sentences with phrase «signals against protein»

«Stop signals against protein clumps: Synthesis of faulty protein chains leads to the formation of toxic aggregates.»

Not exact matches

Researchers at Bonn University, together with collaborators from the Sainsbury Laboratory in Norwich, identified a protein that allows plants to recognize a chemical signal from the worm and initiate immune responses against the invaders.

Cohen's first breakthrough in this area occurred when he discovered, working with worms, that reducing the activity of the signaling mechanism conveyed through insulin and the growth hormone IGF1, a major aging regulating pathway, constituted a defense against the aggregation of the Aβ protein which is mechanistically - linked with Alzheimer's disease.

It is a rare autoimmune disease that results in the body producing antibodies against the NMDA receptor, a protein that plays an important role in signal transduction in the brain.

The scientists could demonstrate the potential of the protein arrays in the context of plant hormone signaling pathways, which, for example, mediate responses to drought stress or against pathogens.

Toll / interleukin -1 receptor (TIR) domain - containing proteins play important roles in defense against pathogens in both animals and plants, connecting the immunity signaling pathways via a chain of specific protein - protein interactions.

My Honours project focused on genetically validating the Signal Transducer and Activator of Transcription 3 (STAT3) protein as a therapeutic target by using a novel transgenetic mouse model in which a short hairpin RNA directed against STAT3 can reversibly be induced by the administration of doxycycline.

Recently, interest has developed regarding the possibility of targeting intracellular inhibitory proteins to improve T cell activity against cancer, including diacylglycerol kinase ζ (DGKζ)(9, 10) and Casitas b - lineage proto - oncogene b (Cbl - b)(11), which attenuate signal transduction events downstream of the TCR and CD28.

Double - Stranded RNA - Binding Protein 4 Is Required for Resistance Signaling against Viral and Bacterial Pathogens