«Something similar occurs in our bodies when we're infected with these viruses; there are
signals our cells detect that let our immune system know all is not well,» he said.
Not exact matches
Biosensors work by
detecting a biological element (enzymes, whole
cells or affinity biomolecules such as antibodies) and relaying the information through an electrical, optical or thermal
signal.
In most vertebrates and some mollusks, the eye works by allowing light to enter it and project onto a light - sensitive panel of
cells known as the retina at the rear of the eye, where the light is
detected and converted into electrical
signals.
We perceive sound after vibrations in the inner ear are
detected by «hair
cells» and transmitted to the brain as electrical
signals.
The inner ear comprises the hearing organ or cochlea, together with the five balance organs (the saccule, utricle and three semicircular canals), which contain the sensory
cells, or hair
cells, that
detect mechanical vibrations and convert them into electrical
signals.
King hypothesizes that proteins that the single -
celled ancestors of animals used to interact with the extracellular environment — to capture bacterial prey by binding to their
cell surface and to
detect chemical
signals — were later repurposed to enable
cells to stick to and talk to each other.
Dr Coleman and her group have developed a sensitive test to allow them to
detect the location and number of the stem
cells after they've been added; they report that the stem
cells do not permanently integrate into the host tissue but instead produce
signals that encourage the host's own
cells to heal the fracture more efficiently.
Brain
cells not normally associated with communication send out a
signal when they
detect blood glucose levels are running low, and this triggers the stomach contractions.
Exactly how they
detect problems was unclear, but researchers now show that they respond to an SOS
signal from dying
cells that is relayed throughout the brain.
Because these light - sensitive
cells are in close contact with nerve bundles, they might be the ones responsible for
detecting visual cues and sending the
signal along the nerves, Sumner - Rooney says.
When a T
cell detects one, it morphs into a fighting machine, zapping invaders with lethal chemicals, multiplying into an army of identical killers or
signaling other immune - system troops to join the attack.
With careful observation and experiments with mouse oocytes, the precursors of eggs, they've
detected molecular
signals that create an asymmetry in the machinery that drives meiosis, the
cell - division process that gives rise to gametes.
Breast cancer
cells were bathed in a nutrient - rich liquid, and, as the cancer
cells grew, the investigators
detected secretions of a
signaling molecule called interleukin - 6 (IL6) in the liquid.
These receptors
detect viral RNA and
signal an innate immune response inside the
cell that is essential for limiting and controlling viral infections.
When an external
signal is
detected by the
cell, the other plasmid is also activated, leading to insertion of its sequences instead.
Normally, when the body
detects an outside invader such as a virus, a
signalling system known as the PKA pathway responds by turning on 99 genes that then activate T -
cells to destroy the invader.
They receive and process
signals from the retina's light -
detecting cells, the rods and the cones, and transmit them to another set of
cells that, in turn, transfer the information to the brain.
These
cells are now thought to serve as the immune system's principal sentinels in the skin — when they
detect damage
signals from nearby wounded skin
cells, they summon other, non-skin-resident immune
cells to the site of the wound.
They have
detected, for example, revved up
signaling molecules involved in inflammation, such as tumor necrosis factor α (TNFα) and other cytokines; skewed populations of natural killer
cells and other immune
cells; imbalances in the protein - destroying enzymes called proteases; and a shortening of the telomeres, the «end caps» on chromosomes, which indicates prematurely aged
cells.
Healthy hair
cells can
detect the magnified sounds from a hearing aid and convert them into neural
signals.
When these photoreceptors
detect light, they send a
signal to specialized neurons in the retina called retinal ganglion
cells, or RGCs, which then transmit visual information to the brain by firing electrical pulses along the optic nerve.
For sensor
cells to receive
signals, he says, there must be a mechanism for transforming the large, weak airborne sound waves into smaller but more powerful fluid - borne sound waves that the sensor
cells can
detect — a process called impedance matching.
We first considered that this could be an experimental artifact, since it is common for developmental genes to be expressed only in a few specific
cells, which could lead to the
signals from the marks being diluted out and not
detected.
As Danny peers at the laptop,
signals stream from more than 60 ultrathin electrodes — each sensitive enough to
detect the murmuring of a single
cell — and into the cables that emerge from his head.
Alterations in the genetic coding for a nerve
cell receptor, which
detects a chemical
signal that is key to behavioral change, could point the way to designing therapies most effective for patients suffering from schizophrenia, drug addiction and other mental illnesses.
Any
signal produced by the rod
cell is then
detected.
Because when the
cell detects an EJC within a certain distance from a «stop»
signal in a gene message, that is when it calls the NMD machinery into action, to halt decoding of the message and resulting in its degradation.
GFP immunoreactivity was
detected in a subset of geniculate ganglion neurons (169/682, 24.8 %; Fig. 2B, C), whereas the P2X3
signal was present in nearly all ganglion
cells (664/682, 97.4 %; Fig. 2B, C).
Moreover; in this study when siRNA was used to knockdown SPRINGTLY, a decrease in
cell proliferation, invasion and increase in pro-apoptotic
signals was
detected [48].
When it comes to defending against DNA viruses, however, the Salk team found something interesting: the
cell's response system begins the same way (with MRN
detecting either DNA or viral breaks) but never progresses to the global alarm
signal in the case of the virus.
Here we show how second messengers relevant to the Gq
signaling pathway can be
detected in living
cells using assays for DAG, PIP2, and Ca2 +.
The receptors
detect hormones and neurotransmitters and then
signal other proteins in the
cell to respond.
Microplate readers can be used to
detect GPCR
signal transduction in living
cells.
Each
detected PNB - specific
signal of such duration will be counted as a confirmation of PC
cell destruction; (2) theranostic dual - pulse treatment: the first pulse will be close to the PNB generation threshold to generate small non-invasive PNBs; upon
detecting such
signals the system will increase the energy to the ablative level and will generate the second pulse in the same direction to expose the same area or volume and to
detect ablative PNBs.
When male SCID / NOD mice were injected with 5 × 106
cells, a baseline
signal was not reported until two weeks after inoculation (Mitsiades et al., 2004), while Azab and colleagues, which inoculated 2 × 106 MM.1S - luc
cells, reported that it took 3 — 4 weeks for sufficient tumor progression to occur and be
detected (Azab et al., 2009).
A blood test can determine whether a person has a low red blood
cell count (which could
signal anemia) or a high white blood
cell count (which could indicate inflammation), while a stool test will help
detect inflammation and rule out infections with similar symptoms to Crohn's disease like C. difficile and E. coli.
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Chemo - receptors in the blood vessels
detect the spike in blood glucose, and then
signal the islet
cells of the pancreas to secrete a hormone called insulin.
This test
detects the small electrical
signals given off by the
cells of the retina when they respond to light.