Sentences with phrase «significant activation of»

The discovery that any kind of art creation resulted in the significant activation of reward feelings are interesting, particularly for art therapists who see art as a beneficial mental health tool.

Not exact matches

Somerville, Mass., April 1, 2010 — Voter Activation Network (VAN), the company whose «VoteBuilder» software helped propel the Democratic Party to a significant technological advantage over the GOP in 2008, announces the release of «VoteSuppressor,» a software program especially tailored to the needs of Republican campaigns.

In 2 cases, the researchers were able to capture «significant» activation of the child's temporal lobes, coinciding with the times they were being exposed to their mothers» voices.

But activation of the Kyoto protocol would still be highly significant, as it would free negotiators to begin to discuss what to do next.

Between - group analysis of phase 2 demonstrated a significant activation cluster in the ipsilateral posterior insula (pIns) in group P. Using the pIns as a seed region the PPI analysis yielded a significant enhanced coupling to the midbrain (periaqueductal grey / ventral tegmental area) after analgesia onset in group A only.

Brain scans taken after the exercise intervention showed a significant decrease in the intensity of brain activation in eleven brain regions while participants correctly identified famous names.

Genetic analysis also revealed significant increase in activity in two genes that may be involved in mitochondria function, suggesting that osteoclast activation might be linked to the reaction of mitochondria to microgravity.

A statistically significant exclusion pattern among PIK3R1, PIK3CA, PTEN and AKT1 mutations (P = 0.025) reflects the well - known activation of PI3K signaling in breast cancer.

The new studies identify activation of endothelial Toll - like receptor 4 by Gram - negative bacteria as a critical event in formation of cerebral cavernous malformations, a significant predisposing condition for stroke and seizure for which effective medical therapies are lacking.

Kessler Foundation researchers published results of their TBI - MEM trial, the first study to demonstrate significant changes in cerebral activation after memory retraining in individuals with traumatic brain injury (TBI).

Chronic schizophrenia patients showed a significant drop in activation of these regions, «thus it appears that they fail to engage these frontal regions,» said Belger.

We found that ~ 90 % knockdown of ABL1 alone resulted in enhanced ABL2 expression and did not produce a significant decrease in the phosphorylation of CrkL, a reporter for the activation state of the ABL kinases (Fig. 2K), and did not inhibit metastasis (Fig. 2, L and M).

Interestingly, we did observe a small but significant reduction in lipopolysaccharide (LPS; via TLR4 and TLR2), TNFα, and IL - 1β — dependent activation of NFκB (Fig. 5C and an approximate IC50 in Fig. 5C, right panel; Supplemental Fig. 3B).

In 2005, the identification of an activating mutation in JAK2 (the V617F mutation) as a STAT5 - activating and disease - causing genetic alteration in a significant proportion of patients with myeloproliferative neoplasms (MPNs) has emphasized the oncogenic role of the JAK tyrosine kinases in hematologic malignancies.2 — 5 JAK2 is a member of the Janus tyrosine kinase family comprising three other mammalian non-receptor tyrosine kinases (JAK1, JAK3 and TYK2) that associate with cytokine receptors lacking intrinsic kinase activity to mediate cytokine - induced signal transduction and activation of STAT transcription factors.6 All JAKs share a similar protein structure and contain a tyrosine kinase domain at the C - terminus flanked by a catalytically inactive pseudokinase domain with kinase - regulatory activity, by an atypical SH2 domain and by a FERM domain that mediates association to the membrane - proximal region of the cytokine receptors.7, 8 Soon after the discovery of JAK2 V617F, we and others described that activating JAK1 mutations are relatively common in adult patients with T - cell acute lymphoblastic leukemia (ALL) and participate in ALL development allowing for constitutive activation of STAT5.9 — 11 Several STAT5 - activating JAK1 mutations were also reported in AML and breast cancer patients.10

The efficacious quality of RIPK2 inhibitor 1 in resolving intestinal inflammation may arise from the fact that it can have a small but significant effect on TNFα -, IL - 1β -, and LPS - driven NFκB activation as seen in Fig. 5 and Supplemental Fig. 3B.

Three recent experimental studies focused on low consumption / exposure.949596 In one study, 29 smokers each consumed a single cigarette, immediately after which they had a significant decrease in blood vessel output power and significant increase in blood vessel ageing level and remaining blood volume 25 minutes later, as markers of atherosclerosis.94 In another study, human coronary artery endothelial cells were exposed to the smoke equivalent to one cigarette, which led to activation of oxidant stress sensing transcription factor NFR2 and up - regulation of cytochrome p450, considered to have a role in the development of heart disease.95 These effects were not seen when heart cells were exposed to the vapour from one e - cigarette.95 A study exposed adult mice to low intensity tobacco smoke (two cigarettes) for one to two months and found adverse histopathological effects on brain cells.96

Jim (University of Missouri, Columbia) has made significant contributions to diverse aspects of plant genetics and plant genetic engineering, ranging from the development of mini-chromosomes and chromosome painting techniques to elucidating the mechanisms underlying centromere activation / inactivation.

Flow cytometry revealed no significant changes in NK cells and CD8 + T cell frequencies in the spleens of the treated mice, suggesting that activation of existing cells was responsible for killing the HIV - LucR - infected cells.

Contrasting the perception of anxiety sweat with sport sweat, significant brain activations were detected in the right insula (BA 44, 47, 48; Fig. 3a), the right precuneus (BA 4, 5; Fig. 3b), the left supramarginal gyrus (BA 40), the right thalamus, the dorsomedial frontal gyrus (BA 6, 8, 9), the right inferior frontal gyurs (BA 44), the right anterior (BA 24) and posterior (BA 23, 29) cingulated gyrus (Fig. 3c), the right substantia nigra, the left fusiform gyrus (BA 37; Fig. 3d), the left cerebellum (BA 19, 30) and the medial vermis (see Table 2).

Comparing results on greater activation of sham acupuncture points than baseline (3c, sham > rest) from 164 subjects, 15 experiments and 200 foci, showed significant convergence in cerebellum, supramarginal gyrus, superior temporal gyrus and thalamus.

No significant differences in ab muscle activation were found between the exercises and all seem to work the midsection muscles equally, with the exception of the crunch, which activates the internal oblique muscles a bit less.

Certain conditions such as Hashimoto's Hypothyroidism, other autoimmune diseases, stubborn acne and PCOS tend to do better off all grains and legumes because of their lectin content, which along with problematic proteins (i.e. gluten in many grains) causes significant inflammation and immune activation for them.

The combination of 5 - HTP and calcium in Cerenity PM provides a significant and natural boost to melatonin levels, aiding in the conversion and activation of this crucial sleep hormone.

It is not healthy for our bodies to be at either of these extremes, but rather in neutral spine which promotes maximum blood flow, healthy muscle activation, and protects our vertebrae, facets and discs of our spine from significant stress and strain.

If you feel like you're about to flip off the bench using a 70 - pound dumbbell but you typically handle 100 - pounds in each hand, then you're probably lacking significant levels of core activation, rotary stability, and full - body tightness.

Conclusion «The lack of significant differences in muscle activation between stable and unstable bench press may allow use of unstable loads by practitioners to add variety to resistance training programs», the researchers concluded.

Sundar Pichai, Senior Vice President at Google, tweeted back in September, to stress the significant data of 1 billion Android activations.

When the datasets of both dogs were combined by spatial warping, activation of the caudate cluster was significant at p < 0.05 after correcting for FDR over the search volume of the ventral brain from olfactory bulb to internal capsule (p < 0.01 height and cluster extent > 6).

Activation of the caudate cluster (CD) was significant at p < 0.05 after correcting for FDR over the search volume of the ventral brain from olfactory bulb to internal capsule (p < 0.01 height and cluster extent > 6).

The contrast of reward versus no - reward hand signals revealed a significant cluster of activation in the region of the right caudate of both dogs (Fig. 3).

Because of the prior hypothesis regarding the caudate, we considered activations in this region significant at p < 0.01 (although p < 0.05 was used to visualize the full extent of activation).

That should have a significant impact on the activation energy of CO2 in a mixed gas environment.

Activation doesn't require significant pressure, yet there's enough travel to provide a hint of tactile feel.

We found significant reduction of symptoms (p < 0.029), and trend - level improvement for schema mode activation (p = 0.054), but not maladaptive schemas (p = 0.291).

This may explain why in their original paper Coan et al [3] observed the regulation of dlPFC activation only by spouse handholding — and why EFT seems to have caused a significant decrease in dlPFC function also by spouse handholding alone.

Interactions between handholding and DAS were detected in the substantia nigra / red nucleus, F (1, 50.0) = 4.0, p =.05, and hypothalamus, F (1, 42.6) = 6.1, p =.02, both due to small positive DAS / activation correlations during the alone condition and small negative DAS / activation correlations during the stranger condition, although none of these correlations was significant.

The construct validity of the scale was supported by significant relationships between activation scores and physicians» ratings of mania and between the depression index scores and clinical ratings of depression.

When we compared the group effects of the secure priming and neutral priming conditions, the contrast (task > baseline) revealed a significant activation in the whole brain analysis.

Beyond this, transference not only prompts goal activation and goal pursuit — when mental representations of significant others are activated — but also specifies both the how and why of goal pursuit based on the activated relationship.

In the current study, we found significant increases in sAA, as a proposed measure of SNS activation, in response to a standardized conflict discussion in couples.