Sentences with phrase «significant alterations»

"Significant alterations" refers to important changes or modifications that have a noticeable impact or effect on something. Full definition
It is now known that cancer results in significant alterations in carbohydrate, protein, and lipid metabolism.
Keeping the core of a fictional story, but making significant alterations.
One of the most significant alterations in this model year involves incidents with other brands and accidental acceleration upon driver attempts to hit the brakes.
Until significant alterations in our approach changes, we will not see a big difference.
The scans of those with brain injuries showed significant alterations in the structure of the brain.
A growing number of scientists have predicted that, if present trends continue, there will be significant alterations in climate patterns from the beginning of the twenty - first century onward.
A further study on the semi-precocious rodent Octodon degus [132] showed that short, repeated separations in the first three weeks of life resulted in significant alterations of density of neurons releasing corticotropin releasing factor (CRF) in brain regions involved in emotion regulation.
From the present study, it was concluded that generalized demodecosis in dogs is associated with significant alteration in trace elements and oxidant / anti-oxidant imbalance and this imbalance might be secondary to changes caused by demodectic mange.»
CHASSIS AND STEERING REFINEMENTS Under the skin, the new 2014 Elantra Sedan Sport trim level has significant alterations aimed at enhancing handling and steering.
They may move through space without suffering significant alteration.
The New York Crossings project has undergone at least one significant alteration since it was unveiled.
In these canine cells we induced a morphological change similar to what happens in cancer progression and we have seen displayed significant alterations in the modulation of genes, called epigenetic lesions,» says Manel Esteller.
Even subtle variations in DCC during adolescence produce significant alterations in prefrontal cortex function later on.
This type of variation can cause significant alterations to the genome and lead to psychiatric disorders, said Sebat, who is a professor and chief of the Beyster Center for Genomics of Neuropsychiatric Diseases at UC San Diego School of Medicine.
Also significant alterations in body composition, lean body mass, body mass index and plasma transthyretin levels.
As part of the procurement process for ninth - through 11th - grade assessments, both ACT and SAT must provide a group of three math and English language arts assessments that are essentially ready - made and do not need significant alterations.
DDC makes such significant alterations to so many systems that it creates tangible changes in the way the 7 - series responds to inputs - and does so without confronting the driver with three million possible combinations of settings.
The most significant alterations include a 100 mm longer wheelbase, a wider front track, a 20 mm lower roofline and a 40 kg weight reduction.
It is also said that the all - wheel drive system in the i30 will require significant alterations to the bodystructure.
The major difference between herbal medicines and western pharmaceuticals is the lack of significant alteration from its natural form.
It's one of the more significant alterations Nordic Games made, and it's something that anyone who hates micro-transactions will be happy to see.
Defense verdict in a case where the defendant doctor admitted significant alterations to the medical chart of the plaintiff's minor.
The standard states that the organization that must comply with the requirements is the one that has authority or approval to build on or make planned significant alterations to the public space, but not necessarily an organization that may have approved the construction or otherwise have an interest in the property.
It has done so in Pt 11 of the Companies Act 2006 (CA 2006): Ch 1 of which clarifies the parameters of the derivative suit in England and Wales and introduces some potentially significant alterations to the common law acquis in this area.
The iPhone's design hasn't changed a great deal from the 6S, with the only significant alterations other than the loss of the headphone socket being the larger and more protruding camera lens, and the two speaker grilles at the bottom of the phone.
Along with the findings that the main cause was a lack of police control, and that there had been significant alteration of statements and other attempts by the police to pass the blame on to the fans, was the conclusion that in 41 cases «what happened... after 3.15 pm was significant in determining the outcome.»
Default retirement The most significant alteration in the sphere of employment law is likely to be felt by employers in the realms of retirement as, after much discussion about the wording of the transitional provisions, last month saw the end of the well - known but not well - loved default retirement age of 65.
CHASSIS AND STEERING REFINEMENTS Under the skin, the new 2014 Elantra Coupe has had significant alterations aimed at enhancing handling and steering.
FINDING THE RIGHT PERSON When you are inviting any professional to make significant alterations to your home, it's always reassuring if they come highly recommended.
Whitehead's last book, Modes of Thought, and his late lecture, «Immortality,» provide evidence that there was no significant alteration of the major doctrines of Process and Reality.)
You can make some easy changes and see if those help the problem, but remember that this is another issue that may lead to significant alterations in your co sleeping arrangement, depending on how things go.
These commonly require a legislative supermajority: in consequence any significant alteration in the existing constitutional arrangements is normally preceded by an often protracted period of scrutiny and consensus building.
«These significant alterations are likely to lead to saltier and more perennial streamflows throughout Appalachia, where at least 7 percent of the land has already been disturbed by mountaintop - removal mining,» says Nippgen, who notes that mountaintop removal is not part of Wyoming's coal industry.
Scientists who choose to do their postdoctoral work in industry must deal with another significant alteration in mindset.
There were significant alterations in SIDS cases compared with controls occurring in 2 patterns (Table 3).
At the end of the trial period, the researchers did not recorded any significant alterations of in respect of body weight or body fat percentage.
Prior research by the same researchers on the effects of glucose and caffeine consumption showed improvements in declarative memory and attention span with no significant alteration of the subjective state of the individuals.
«The results of this study demonstrate that there are significant alterations in the expression of ER - alpha and ER - beta in PCOS that may be related to abnormal follicular development,» Magoffin et al conclude.
Over the course of this third solo outing for the god of thunder, Thor will lose his allies, his freedom, those flowing golden locks, and also something more permanent, but none of these will be the most significant alteration to the character in Taika Waititi's zippy, slightly tilted, often joyfully frenzied film: Thor is finally in on his own joke.
Beta testing the MMORPG has led to some significant alterations to the UI, like adopting a more Skyrim-esque compass instead of their bulkier minimap.
Outside, significant alterations have sharpened the look, and you'd be forgiven for seeing hints of the Ford Explorer, itself a good - looking mid-size SUV.
Likewise, we expect the new CC's pricing not to receive any significant alterations either.
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