Sentences with phrase «significant burden»

Critics of more liberal immigration policies claim that such migrants from low - income countries are «cast - offs» and impose significant burden on host communities.

The present technique can realize a more diverse, higher - level genome editing operation as it can efficiently conduct intended modification in a way that does not put significant burden on the cells.

We know these plans for current spending in 2015 - 16 are likely to place a very significant burden on public services.

Money worries, health problems and even the sharing of household chores can place significant burdens on all family relationships.

Research and reporting evaluating the effect of abortion restrictions in Texas found that health center closures resulted in significant burdens for women, including delay, increased travel distances, high out - of - pocket costs, and overnight stays.

As one Native Title Service Provider (NTSP) commented, the current nature of the law «and the lack of substantive reform — results in significant burdens of proof and contributes to the fostering of unsustainable relationships with other stakeholders».

He and Young bear some pretty significant burden of proof.

Director Rich Cordray gave a presentation in which he said, «Student loan debt is one of the most significant burdens facing our young people, and it certainly hits close to home for a growing number of Americans.»

Next to Medicaid, pension costs are the most significant burden on local governments.

ADLI Law Group recognizes that litigation imposes significant burdens upon our business clients.

Even though the document does place Bitcoin exchanges under a very significant burden of regulation, what it also means is that nothing worse is going to come.

... very significant burden on some PBCs and that compulsory consultation should only be applied to decisions to surrender native title rights and interests in land or waters.33

Right now it requires a pretty significant burden to indict someone on their speech and it should be that way.

The regulatory environment can pose significant burdens to life sciences companies, but intelligent strategic advocacy on Capitol Hill and appropriate engagement of federal regulatory agencies can also provide new markets and opportunities for innovative products.

According to CEO John Chen, the move positions the company for growth and removes a significant burden on its balance sheet.

In the workplace, if you think about all of the different forms of identity or proof that you are who you say you are and that you have access to what you say you do, that's already a significant burden on workers.

That European law could put a significant burden on digital platforms and advertisers to obtain clear consent from consumers when using their digital data.

per borrower, is a significant burden for more than 40 million Americans.

There is no debt more stifling than student loan debt, which, at average of more than $ 30,000 per borrower, is a significant burden for more than 40 million Americans.

Staff appreciation programs can be implemented without major budgetary strains, or any significant burden to management.

A duty to die is more likely when continuing to live will impose significant burdens — emotional burdens, extensive caregiving, destruction of life plans, and, yes, financial hardship — on your family and loved ones.

Crabbe is not a capable facilitator or creator to flourish in a role without a creator making his shots for him, while Middleton for a large part was able to carry a significant burden for the bucks as a primary option.

Moreover, formula feeding imposes a significant burden on the nation's economy.

As health care professionals, not being able to provide a clear reason for the death is also a significant burden.

The high cost of maintaining such a large military posed a significant burden on the comparatively badly developed and inefficient Soviet economy.

So, the court ruled that Photo ID requirement doesn't place an undue or significant burden on the right to vote:

When the income level of the sponsor is this low, there is an obvious risk that the migrants and their family will become a significant burden on the welfare system and the taxpayer.

They have no revenue yielding potential, and at the same time impose a significant burden on the private sector and on the average Ghanaian citizen.

He comments: «Osteoarthritis causes a significant burden to individuals and the healthcare system as a whole.

Basal cell carcinoma is one of the most common cancers and its incidence is increasing worldwide, putting a significant burden on health services.

There is a significant burden in cost of care and quality of life for people suffering from this disability.

«The findings from this trial are very encouraging to those of us who have spent many years working on vaccine candidates to protect against dengue, a disease that is a significant burden in much of the world and is now endemic in Puerto Rico,» said Stephen Whitehead, Ph.D., of NIH's National Institute of Allergy and Infectious Diseases (NIAID).

Complex wounds are a significant burden on patients and on the economy, costing the North American health - care system $ 10 billion a year.

Our results suggest the need for future studies involving long - term ambulatory cardiac monitoring to better delineate the risk associated with transient vs persistent perioperative AF, as well as randomized clinical trials to determine optimal strategies for antithrombotic therapy in patients with perioperative AF and a significant burden of other risk factors for stroke,» the authors write.

While this therapy is effective, patients must self - inject FVIII product twice or three times every week intravenously, which represents a significant burden on these patients and their families.

The American Journal of Nursing paper concludes: «We believe that in tackling the significant burden of post critical illness physical, psychological, and cognitive morbidity, the CCRC presents a bold and innovative step to modify these PICS symptoms and to improve ICU survivors» quality of life.

«For patients and families, uncertainty is a significant burden,» he continues.

Four genes also exhibited a significant burden of rare damaging variants, suggesting a functional link to disease risk.

Uterine leiomyomas, also called fibroids, cause a very significant burden to women's health but relatively little has been known about the mechanisms of tumorigenesis involved.

And because MCFAs do not place a significant burden on the pancreas (since they require no digestive enzymes), they help the pancreas to more efficiently produce and use insulin.

Autoimmune disease affect over 23 million Americans causing a significant burden to society and the quality of life.

I don't recommend other yogurts as the lactic acid content from the fermentation is a significant burden to your liver.

I'd make sure to emulate the behaviour of screen items changing state, as the cursor rolled over them, and this placed a significant burden on the development effort.