Sentences with phrase «significant burdens of»

Feeding babies with formula does, of course, require additional preparation time and equipment when there are two or more babies and, even for mothers with adequate help at home (which not all women have), this can be a significant burden of both time and expense.

Our results suggest the need for future studies involving long - term ambulatory cardiac monitoring to better delineate the risk associated with transient vs persistent perioperative AF, as well as randomized clinical trials to determine optimal strategies for antithrombotic therapy in patients with perioperative AF and a significant burden of other risk factors for stroke,» the authors write.

The American Journal of Nursing paper concludes: «We believe that in tackling the significant burden of post critical illness physical, psychological, and cognitive morbidity, the CCRC presents a bold and innovative step to modify these PICS symptoms and to improve ICU survivors» quality of life.

Four genes also exhibited a significant burden of rare damaging variants, suggesting a functional link to disease risk.

By performing a meta - analysis of rare coding variants in whole - exome sequences from 4,133 schizophrenia cases and 9,274 controls, de novo mutations in 1,077 family trios, and copy number variants from 6,882 cases and 11,255 controls, we show that individuals with schizophrenia carry a significant burden of rare, damaging variants in 3,488 genes previously identified as having a near - complete depletion of loss - of - function variants.

When work and family responsibilities become so all consuming that women have no time for female friendships, this can add a significant burden of stress onto busy women's lives.

Even though the document does place Bitcoin exchanges under a very significant burden of regulation, what it also means is that nothing worse is going to come.

This is because the non-Indigenous policies and structures that govern the native title process require us to endure the significant burden of proving that our connection to our country exists — even though the experience of colonialism has taken many of us from our country and the meaning of land and resources has changed to accommodate non-Indigenous legal and commercial values.

Not exact matches

In the workplace, if you think about all of the different forms of identity or proof that you are who you say you are and that you have access to what you say you do, that's already a significant burden on workers.

Hernandez's defense, led by Michael Fee, however, spun the conversation as proof of a close friendship between the men, which could lead the jury to question Hernandez's motive for murder, a significant element in the burden of proof for the prosecution.

While residents in the above states pay lower taxes compared to those in places like New Jersey, there are still «plenty of Americans are facing a significant tax burden,» GOBankingRates says.

Also, more controversial provisions — such as requirements to execute enforceable written contracts under the Best Interest Contract and Principal Transactions Exemption, and changes to PTE 84 - 24 (other than the addition of the Impartial Conduct Standards)-- are not applicable until January 1, 2018, while the Department is honoring the President's directive to take a hard look at any potential undue burdens and decides whether to make significant revisions.

The United States Chamber of Commerce has also objected to his Buy American stance, claiming that whenever the government has enacted domestic sourcing rules in the past, «the resulting experience has been higher overall construction costs, increased compliance burdens, reduced competition, and disruption of supply chains without significant American job creation.»

They have a significant impact on almost every area of personal finance, and much of the planning we do is intended to reduce our tax burden.

The company aims to increase digital ordering and its base of app users, driving a lot of traffic without imposing a significant labor burden on staff, Li explained.

This is sound policy as far as it goes, but the question arises as to how to finance significant deficits over a period of time without unduly increasing the public debt burden.

In addition, indicators of financial stress — such as loan arrears — remain low, suggesting that the high debt - servicing burden is not yet imposing a significant constraint on consumer spending.

Proactive tax planning minimizes our clients» tax burdens and builds a solid foundation of tax - reduction strategies that can result significant tax savings.

There is no debt more stifling than student loan debt, which, at average of more than $ 30,000 per borrower, is a significant burden for more than 40 million Americans.

A duty to die is more likely when continuing to live will impose significant burdens — emotional burdens, extensive caregiving, destruction of life plans, and, yes, financial hardship — on your family and loved ones.

The IRS, of all groups, has come out on the side of taxpayers, writing in 2015 that «the IRS's approach to FATCA implementation has created significant compliance burdens and risk exposures to a variety of impacted parties.»

Is commitment to God finally one of those crushing burdens that, in claiming to make our life significant, actually mutilates us?

To confess that power and lovingkindness belong to God is to relieve ourselves of a significant existential burden, and also to accept an ethical mandate.

It is significant that over the years the Dodgers have been unable to find in their annual glitter of rookies one really outstanding player to share the Dodger burden.

The first author of the study, Chandran Alexander, assistant professor of pediatrics at Penn State College of Medicine, said, «Mothers» significant others have a role to play in reducing the burden of colic.

A package of proven prevention and treatment measures are now available that, if taken to scale, would have a profound impact on reducing child deaths and would lead to a significant reduction in the diarrhoea burden in the medium to long term.

«We applaud the members of the Senate Republican Conference for championing these reforms and taking significant steps to ease the cost burden borne by every employer in the state — especially Upstate,» said Greg Biryla, the executive director of the Rochester - based Unshackle Upstate.

«While we understand the significant cost of complying with the recent court rulings overturning decades of New York State policy on 24 - hour homecare cases, we strongly believe that it is unfair to continue to ask home care workers to bear the financial burden of providing needed round - the - clock care.»

While Medicaid represents the single largest cost to Erie County, more than $ 211.7 million this year alone — the local share of more than $ 1 billion annually — prior administrations failed to take significant action to help reduce this burden on local taxpayers.

adoption of a real property tax cap, as advocated by Governor Paterson, coupled with significant mandate reform and local government consolidations - actions that would reduce the enormous size and cost of local government, and the state's crippling real property tax burden.

«Exempting the provision of workplace electricity will remove a significant administrative burden in calculating what is often a relatively small sum.

Burden described the change as «a significant shift of bulk away from the High Line along 10th Avenue that will greatly improve the feeling of openness from both the north and the south.»

ALBANY, NY (02/10/2014)(readMedia)-- The Business Council of New York State, Inc. presented testimony today outlining how the adoption of the Executive Budget's business tax reform provisions will lower business tax burdens and produce significant job, income and economic benefits for the state.

«There will be significant cuts, but they must be thoughtful, deliberate, and not place an unfair burden on the backs of seniors, our children, veterans or our most vulnerable citizens.»

As the Rokita court noted, voters who lack Photo ID undoubtedly exist somewhere, but the fact that Plaintiffs, in spite of their efforts, have failed to uncover anyone «who can attest to the fact that he / she will be prevented from voting» provides significant support for a conclusion that the Photo ID requirement does not unduly burden the right to vote.

«We would be very concerned indeed if this proposal goes ahead without significant consultation since the additional burdens for self - employed people both in terms of administration and potential costs will almost certainly be substantial enough to discourage entrepreneurship altogether.

Nonetheless, the burden of compromise fell heaviest on the Liberal Democrats; and within the Programme for Government coalition agreement a significant number of their flagship policies were diluted (e.g. electoral reform), forestalled (e.g. House of Lords reform) or disregarded entirely (e.g. UK - wide federalism).

If the Governor and Legislative Leaders are going to talk the talk about tax reform they better walk the walk with results or taxpayers will make them walk the plank in the deep waters of the 2014 election with the heavy burden of failing to fulfill the promise of significant tax relief!»

Significant mandate relief is sorely needed to free all 62 counties of the burden of paying for Medicaid.

But, if one assumes realpolitik has a significant presence in New York's Legislature and there's pressure to come to some sort of compromise ethics agreement in this year's budget, it's easy to imagine a scenario in which lawmakers prefer to burden their allies rather than themselves.

The passage of the bills, known collectively as the Criminal Justice Reform Act and spearheaded by the Council speaker, Melissa Mark - Viverito, was the most significant step yet toward reducing the burden of a two - decade - old policing policy that treats public disorder as harbingers of more dangerous offenses, and has resulted in hundreds of thousands of outstanding criminal court warrants for minor infractions.

As associate professor and first - author Johan Bollen writes in an e-mail to Science Careers, they wanted their new system to «enable scientists to set their own priorities, fund scientists... not projects, avoid proposal writing and reviewing, avoid administrative burdens, encourage all scientists to participate collectively in the definition of scientific priorities, encourage innovation, reward scientists that make significant contributions to data, software, methods, and systems, avoid funding death spirals (no funding - > no research - > no funding) but still reward high levels of productivity, create the proper incentives for scholarly communication (publishing to communicate, not to improve bibliometrics), enable funding of daring and risky research, and so on.»

Conversely, the large volume of surgeries performed annually means that the population burden of long - term postoperative opioid use remains significant.»

This candidate vaccine has the potential to have a significant impact on public health in view of the high disease burden in endemic countries.»

«Despite this significant clinical burden, there is a general lack of objective evidence to guide wound management,» Dr. Kim said.

Basal cell carcinoma is one of the most common cancers and its incidence is increasing worldwide, putting a significant burden on health services.

IBS accounts for 10 per cent of visits to GP surgeries and the condition has a significant and escalating burden on society as a consequence of lost work days and time spent on regular hospital appointments.

Third, M.D.s often graduate from medical school with significant financial debt; remediation of basic - science deficiencies extends training, prolonging and increasing financial burdens.

Non-rechargeable batteries already created significant amount of landfill, imposing serious environmental burden on industrialized societies.

In a move unprecedented in Canada, the University of Toronto has taken a significant step to alleviate some of the financial burdens grad students bear.