Sentences with phrase «significant change of pace»

Not exact matches

David Solomon, president and co-chief operating officer of Goldman Sachs, discusses how the significant growth of tech giants in 2016 and the pace of technological change is leading to «significant strategic shifts» as companies reevaluate their business strategies.

The pace of innovation in healthcare has accelerated in the last decade due to changing demographics and significant unmet medical needs.

The pace of innovation in healthcare has accelerated in the last decade due to demographic changes and significant unmet needs in major disease areas like cancer and neurodegenerative disorders.

Three significant characteristics of lasting change include sustainability, consistency, and pacing.

The ambitious targets of tech entrepreneurs also create a high - pressure environment and the fast pace of change in the tech industry leaves many entrepreneurs facing a significant growth challenge.

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

Although the pace of change has already been very rapid, a significant number of the measures outlined above are due to take effect in 2017.

This highly unusual characteristic may enable the variants to help to maintain a fundamental tension crucial for evolutionary success: promoting the generation of significant diversity within a portion of the population but keeping the pace of this change within certain bounds, maintaining it relatively constant overall and so supporting the stability of the genome and the cohesiveness of the species.

The way students learn and educators teach is changing at an unprecedented pace, with 49 % of educators believing the foreseeable future will bring significant changes to the way they teach *.

The education secretary has in her grasp some key levers to head off the perfect storm that is beginning to gather: in seeking information, before the election, about the workload challenges facing schools, she knows that: Ofsted needs extensive reform, possibly replaced with validated peer - to - peer accountability and the incoherent sequencing and pace of curriculum changes need to be rethought with school leaders thinking about what will have a significant impact on children's learning.

It doesn't really change the gameplay in any significant way, but seeing it brought back was a refreshing change of pace.

By the time he worked on the paintings in this exhibition, John Hoyland: Stain Paintings 1964 — 1966 at Pace (September 25 — October 21, 2017), his work had undergone a number of significant and radical changes.

Hence: http://www.nature.com/nclimate/journal/v4/n4/full/nclimate2161.html, and Greenland's ice loss has doubled since the early 2000s http://www.bbc.com/news/science-environment-28852980 and its ice melt is accelerating http://www.rtcc.org/2014/04/14/greenland-ice-melt-accelerating-say-scientists/) An extremely comprehensive study in 2012 found that «the pace of ice loss from Greenland is extraordinary, with nearly a five-fold increase since the mid-1990s, http://goo.gl/rkHa9J Changes in rates of increase are significant.

[2] In addition to the risks from spills, the burning of heavy fuel oil by ships emits significant quantities of black carbon, potent in accelerating the already rapid pace of Arctic climate change.

This level of cost reduction is hopefully possible to accomplish with massive investments in R&D, but there is significant risk that such cost reductions will not happen at the pace needed to curtail climate change.

Humans have been changing Earth's landscapes at globally significant levels for at least 3000 years, and doing so by increasingly productive and efficient means, according to our new research challenging the claim that use of land by industrial civilization is destroying planetary ecology at an accelerating pace.

For my part, I would be both surprised and disappointed to see any significant diminution in the volume of legal publishing that is undertaken but I would be surprised if the pace of change in formats and methods of communication, perhaps with, to some extent, a reduction in the amount of scholarly publishing, are not likely outcomes.

Undoubtedly, this has to do with the pace of change in tax and customer characteristics but I think that a significant reason is that the law publishers, with their legacies, have more to lose from abandoning books and print subscriptions and use lack of customer push as an excuse for maintaining the status quo.

With an uplift in the market and a real change of pace, we expect to see a number of significant deals coming to fruition this year.

Amidst the rapid pace of innovation and changing consumer expectations, Accenture has released Fjord Trends 2016, its ninth annual report examining the most significant emergent digital trends expected to transform design, organizations and society in the year ahead.