Sentences with phrase «significant changes in the current»

However, hypoxia - associated genes, Flt - 1 and EPOR, showed no significant changes in the current study.

Wes Bolsen, CMO and head of government affairs at Coskata, discussed a recent Sandia National Labs and General Motors study demonstrating that 90 billion gallons of feedstock - flexible ethanol is possible in the U.S. without a significant change in current land use.

Not exact matches

As someone who teaches and advises in the field and has an obligation to keep current with emerging developments, given the significant rate of change in the last ten years, I could not imagine how a director of a company could remain current without ongoing requirements rather than passing familiarity or osmosis (I am speaking here of directors who have chosen not to upgrade their education).

Such statements are based upon the current beliefs and expectations of management and are subject to significant risks, uncertainties and changes in circumstances that could cause actual outcomes and results to differ materially.

There can be a successful European Union, and many of the changes that are needed to ensure success are likely to be relatively easy to implement, especially if they are part of an overall package that includes significant debt restructuring and forgiveness, but the current structure is not in place.

Continental Europe, Japan, and the UK are the only developed economies large enough to absorb a significant change in the volume of capital inflows, but none of them are eager to absorb the current account implications.

Many factors could cause BlackBerry's actual results, performance or achievements to differ materially from those expressed or implied by the forward - looking statements, including, without limitation: BlackBerry's ability to enhance its current products and services, or develop new products and services in a timely manner or at competitive prices, including risks related to new product introductions; risks related to BlackBerry's ability to mitigate the impact of the anticipated decline in BlackBerry's infrastructure access fees on its consolidated revenue by developing an integrated services and software offering; intense competition, rapid change and significant strategic alliances within BlackBerry's industry; BlackBerry's reliance on carrier partners and distributors; risks associated with BlackBerry's foreign operations, including risks related to recent political and economic developments in Venezuela and the impact of foreign currency restrictions; risks relating to network disruptions and other business interruptions, including costs, potential liabilities, lost revenues and reputational damage associated with service interruptions; risks related to BlackBerry's ability to implement and to realize the anticipated benefits of its CORE program; BlackBerry's ability to maintain or increase its cash balance; security risks; BlackBerry's ability to attract and retain key personnel; risks related to intellectual property rights; BlackBerry's ability to expand and manage BlackBerry (R) World (TM); risks related to the collection, storage, transmission, use and disclosure of confidential and personal information;

Many factors could cause BlackBerry's actual results, performance or achievements to differ materially from those expressed or implied by the forward - looking statements, including, without limitation: BlackBerry's ability to enhance its current products and services, or develop new products and services in a timely manner or at competitive prices, including risks related to new product introductions; risks related to BlackBerry's ability to mitigate the impact of the anticipated decline in BlackBerry's infrastructure access fees on its consolidated revenue by developing an integrated services and software offering; intense competition, rapid change and significant strategic alliances within BlackBerry's industry; BlackBerry's reliance on carrier partners and distributors; risks associated with BlackBerry's foreign operations, including risks related to recent political and economic developments in Venezuela and the impact of foreign currency restrictions; risks relating to network disruptions and other business interruptions, including costs, potential liabilities, lost revenues and reputational damage associated with service interruptions; risks related to BlackBerry's ability to implement and to realize the anticipated benefits of its CORE program; BlackBerry's ability to maintain or increase its cash balance; security risks; BlackBerry's ability to attract and retain key personnel; risks related to intellectual property rights; BlackBerry's ability to expand and manage BlackBerry ® World ™; risks related to the collection, storage, transmission, use and disclosure of confidential and personal information; BlackBerry's ability to manage inventory and asset risk; BlackBerry's reliance on suppliers of functional components for its products and risks relating to its supply chain; BlackBerry's ability to obtain rights to use software or components supplied by third parties; BlackBerry's ability to successfully maintain and enhance its brand; risks related to government regulations, including regulations relating to encryption technology; BlackBerry's ability to continue to adapt to recent board and management changes and headcount reductions; reliance on strategic alliances with third - party network infrastructure developers, software platform vendors and service platform vendors; BlackBerry's reliance on third - party manufacturers; potential defects and vulnerabilities in BlackBerry's products; risks related to litigation, including litigation claims arising from BlackBerry's practice of providing forward - looking guidance; potential charges relating to the impairment of intangible assets recorded on BlackBerry's balance sheet; risks as a result of actions of activist shareholders; government regulation of wireless spectrum and radio frequencies; risks related to economic and geopolitical conditions; risks associated with acquisitions; foreign exchange risks; and difficulties in forecasting BlackBerry's financial results given the rapid technological changes, evolving industry standards, intense competition and short product life cycles that characterize the wireless communications industry.

At the same time, the community should advocate for necessary change and self - regulate in areas where there are significant risks of public harm that have not been addressed by current law.

The movement of price provides evidence of the current trend, but the MACD is flagging up changes in momentum which can sometimes precede a significant price reversal.

But with their current management problems, it is more likely that they may stay in the Championship for quite some time unless there is a significant change at the top.

The current and projected future impacts of climate change on nature in Massachusetts are very significant, requiring a thoughtful and comprehensive approach and a sustained effort.

Dana has intimate familiarity with what it takes to make significant changes in a large, urban district like my own, and she is less - than - starry - eyed about the ability of any other district to follow suit without outside funding — over and above the current USDA reimbursement rate, OR that amount plus six cents.

In a letter to the chairman of LAG, environment secretary Liz Truss MP said the report «did not show that the impacts of lead ammunition were significant enough to justify changing current policy».

In interviews, de Blasio administration officials and Albany lawmakers agreed that a three - year extension was the easiest way to maintain the current system of mayoral control without significant changes, a win for de Blasio.

City politicians past and present have come out in support of renaming the Queensboro Bridge in Long Island City after former Mayor Ed Koch, but City Councilman Peter Vallone Jr. (D - Astoria) said the bridge's current name is too significant to be changed.

However, the VDC plan also has several significant advantages: members vest in a year, compared to 10 years years for any current DB pension plan; they can control their own investment profile with the advice of experts; and the DC plan is portable, meaning it follows employees when they change jobs in the public or private sectors, in or out of New York.

The paper states: «Even though the ambient air in the city of Jena is comparably clean, the significant association between rapid changes in nitrogen oxides and onset of myocardial infarction (MI) suggests that the current EU statutory limits do not sufficiently protect against effects relating to the cardiovascular health of the population.

«Using a numerical climate model we found that sulfate reductions over Europe between 1980 and 2005 could explain a significant fraction of the amplified warming in the Arctic region during that period due to changes in long - range transport, atmospheric winds and ocean currents.

«There is a significant difference in what the President would like to be investing in clean energy technology and what Congress seems at the current moment to be inclined to invest,» he said, adding that he believes «there is a good chance of that picture changing.»

By and large, current methods are essentially switches to turn the neuron on or off and can produce dramatic changes in neuronal activity that can manifest in significant behavioral changes.

New Zealand has been faced with the changes and challenges of significant health reforms yet there remains little published literature about health professional job satisfaction and levels of psychological distress in the current working environment.

- Patient in need of significant lifestyle changes (e.g. diet, exercise, sleep, stress management)- Patient is self - prescribing supplements, herbs, vitamins or natural therapies - Patient interested in natural approach to ailment - Natural Medicine Consult / Patient not progressing with current treatment - Adjunctive / supportive therapy needed for continuation of conventional treatment / side effect reduction

The other significant change over that period was the use of the revers in the construction of the lapel, as the Victorians used elaborate three - part patterns to cut a fold of cloth from the lining into the front of the lapel, a universal consideration of frock coats and dress coats of the period, but abandoned in favor of the current single - piece lapels at the same time as the switch to morning coats and lounge suits.

Significant changes have been made to the Teachers» Pension Scheme, but also there have been changes to the way that pensions can be accessed in the form of the Freedom and Choice initiative and also the new State Pension that replaces the current two tier Basic State Pension and Additional State Pension.

To this end, our current work plan is focused on three core objectives: (1) To build a dynamic «Frontiers of Innovation» community composed of scientists, scholars, policymakers, policy analysts, practitioners, and other creative individuals who are motivated to engage in the kind of transformational thinking that is needed to break down disciplinary barriers and catalyze significant change in early childhood policy and practice.

Teachers pay and benefits are set to undergo significant changes; September 2013 sees the introduction of performance related pay; and don't underestimate the difficulties of coping in the current economic climate.

We don't anticipate any significant pricing changes for the 2015 Ford Focus ST, which comes in ST1, ST2, and ST3 trim levels, so expect something close to the current car's $ 24,450 starting price when the updated 2015 model goes on sale later this year.

Audi engineers made some significant changes in the car's basic blueprint that improve its overall driving dynamics when compared with the current A4.

NVH IMPROVEMENTS HAPPEN AT HYUNDAI SPEED Since the launch of the current generation in 2010 as a 2011 model, Elantra has undergone significant changes to reduce cabin noise.

While styling will closely parallel the current version and its 4.5 - litre turbo - diesel V8 remains unchanged in displacement and outputs, significant changes to the car's gearing and ECU are expected to elicit better response and driveability than before, without forgoing the car's traditional utilitarian edge.

Since the launch of the current generation in 2010 as a 2011 model, Sonata has undergone significant changes to reduce cabin noise.

The new spy shots do not allow us to discover significant differences compared to the current model, but confirmed the slight increase in length, with changes even lower to maximize interior space.

The first and second generation Mercedes A-Class had a tallboy design, while the current third generation Mercedes A-Class got significant design change, when it was launched globally in 2012.

NVH IMPROVEMENTS HAPPEN AT HYUNDAI SPEED Since the launch of the current generation in 2012 as a 2013 model, Elantra Coupe has undergone significant changes to reduce cabin noise.

* Training / Behavior Modification hasn't resulted in an acceptable change in the dog; * There is significant risk and / or evidence that dog is going to seriously injure someone; aggression problems don't automatically mean the dog will injure someone or is dangerous; I am referring to the idea that even with reasonable precautions, supervision, training and behavior modification, the dog is still going to get around all of that and hurt someone; * You have made a reasonable effort to work with the dog and situation; meaning you have PAID a professional to help you, worked the situation properly and diligently, and you still can't trust the dog to not hurt itself, another animal or a person; * The dog is so dangerous you can't place the dog with someone else; * The owner isn't willing, or is unable, or unqualified, to work with the dog any further, even with supervised professional help; some people won't follow instructions, so some of these dogs would be fine in the hands of someone else, but not the current owner; * Regardless what you do (behavior modification, training, and / or behavioral medications) nothing has made the dog manageable, and your trainer is recommending you consider euthanasia; * Even behavioral medications can't alleviate the problem; I am experienced working with drugs prescribed by veterinarians and can give you feedback as to how things are going, or when you might wish to consider another drug; * This dog is too dangerous to work with.

Following their historic lead, there's truth to the old adage that birds of a feather flock together, as there are numerous women in contemporary society that continue to effect change globally in the way art is perceived, understood and collected, among them Agnes Gund, the current President Emerita of MoMA; Sheikha Al Mayassa Al Thani, who at 31 is the Director of the Qatar Museum Authority with an unlimited acquisition budget; Emily Fisher Landau, famed art collector and philanthropist, who founded the Fisher Landau Center for Art and is a trustee and generous donor for the Whitney Museum of American Art; Rosa de la Cruz, who with her husband Carlos, founded the de la Cruz Collection Contemporary Art Space (Miami), which provides education and awareness in the visual arts; Dasha Zhukova, the formidable founder of the most significant private art foundation in Russia, the Garage Museum of Contemporary Art; and Miuccia Prada, CEO of Prada fashion and co-founder of Fondazione Prada, which promotes contemporary art and other arts - related interests; all of these remarkable women share the passion that Beth has developed for the arts and artists.

So, the honest answer in statements to the press regarding extreme weather events is this: «climate change is happening and is possibly a factor in this weather (or hurricane) event but our current understanding shows no significant (or some) correlation.

It is possible, therefore, that the effects of recent accelerations in climate change have not yet started to have a significant contribution to or impact on current sea levels; but based on international scientific opinion, it is more a case of when, rather than if.

Research indicates that the Arctic had substantially less sea ice during this period compared to present Current desert regions of Central Asia were extensively forested due to higher rainfall, and the warm temperate forest belts in China and Japan were extended northwards West African sediments additionally record the «African Humid Period», an interval between 16,000 and 6,000 years ago when Africa was much wetter due to a strengthening of the African monsoon While there do not appear to have been significant temperature changes at most low latitude sites, other climate changes have been reported.

So, yes, I do think that there is a reasonable case to be made that climate change had a significant role in the current Syrian mess.

Given projected increases in the frequency and intensity of extreme precipitation events in the Midwest (Chapter 2: Our Changing Climate, Key Message 6), 57 it appears that sewer overflow will continue to constitute a significant current health threat and a critical source of climate change vulnerability for major urban areas within the Midwest.

Older people are at much higher risk of dying during extreme heat events.136, 50,241,233 Pre-existing health conditions also make older adults susceptible to cardiac and respiratory impacts of air pollution25 and to more severe consequences from infectious diseases; 257 limited mobility among older adults can also increase flood - related health risks.258 Limited resources and an already high burden of chronic health conditions, including heart disease, obesity, and diabetes, will place the poor at higher risk of health impacts from climate change than higher income groups.25, 50 Potential increases in food cost and limited availability of some foods will exacerbate current dietary inequalities and have significant health ramifications for the poorer segments of our population (Ch.

Continue current trajectory - decline, change direction and possible significant economic growth in the sector.

Oleg Sorokhtin of the Russian Academy of Sciences Institute of Ocean Studies, and many other Russian scientists maintain that global climate depends predominantly on natural factors, such as solar activity, precession (wobbling) of the Earth's axis, changes in ocean currents, fluctuations in saltiness of ocean surface water, and some other factors, whereas industrial emissions do not play any significant role.

Changes in downwelling and upwelling currents might well have significant oscillatory (periodic or non-periodic) effects over a wide range of periods, but it is certainly possible to set some limits on the strength of these effects.

They explain how, overall, Antarctic sea ice cover (frozen sea surface), for separate reasons involving wind changing in relation to the location of certain warming sea water currents, shows a slight upward trend, though it also shows significant melting in some areas.

But a quick glance at current funding guidelines and the latest list of grants by the key players in the Environmental Grantmakers Association — which includes representatives from 250 foundations around the world — shows little significant change.

A significant and serious concern among mainstream climate scientists in this regard is the inability of the models to predict climate surprises, that is, rapid non-linear changes in the climate system that have happened in the historical climate record and that may be triggered by current human activities.

This puts me roughly in the same camp as James Annan, though possibly I am less skeptical that there could be benefits for moderate warming, and I am probably more skeptical of claims about the supposedly significant level of damage from the current level of anthopogenically induced climate change.