Sentences with phrase «significant changes in the expression»

Utilizing this very sensitive technique they were able to demonstrate significant changes in the expression of over 4000 genes.

Based on the CT based anatomical observations in probainognathians, it appears that the MSX2 gene underwent a significant change in its expression 240 - 246 million years ago and triggered the evolution of many typical mammalian traits including hair and whiskers, an enlarged cerebellum, complete ossification of the skull roof, and more importantly, the mammary glands, that define mammals today.

But the researchers found no significant changes in the expression of genes known to be involved in calcification from prior studies comparing strains with dramatically different calcification levels.

In control bees kept under anesthesia, there was no significant change in the expression level at any time - point sampled.

Not exact matches

In collaboration with Yi Xing from UCLA, the team catalogued and analyzed how gene expression patterns in skin cells differed among the Esrp knockouts and found hundreds of significant changeIn collaboration with Yi Xing from UCLA, the team catalogued and analyzed how gene expression patterns in skin cells differed among the Esrp knockouts and found hundreds of significant changein skin cells differed among the Esrp knockouts and found hundreds of significant changes.

When Bordenstein and Brucker compared gene expression patterns in normal and microbe - free offspring, they found significant changes in many of the genes involved in the immune response (Science, doi.org/m87).

The genomics era has had a profound impact on life science research, leading to significant developments such as the use of expression quantitative trait loci (eQTLs), which link polymorphisms in single genes to quantifiable changes in gene expression associated with specific diseases.

The team found significant changes in gene expression after light exposure in all cell types in the visual cortex — both neurons and, unexpectedly, nonneuronal cells such as astrocytes, macrophages and muscle cells that line blood vessels in the brain.

Mao's study examined mitochondria - associated gene expression in the mouse eye tissue and found significant changes in several genes involved in oxidative stress response.

«We observed small but significant changes in the gene expressions between normal and diabetic corneas,» said Mehrnoosh Saghizadeh Ghiam, PhD, assistant professor of biomedical sciences and neurosurgery, a researcher in the Regenerative Medicine Institute Eye Program and the lead author of the study published in the journal PLOS ONE.

Based on analyses of over 600 drug and breast cancer cell pairings, researchers showed that, for some cells, drug exposure can cause significant changes in gene expression — indicating the successful action of a drug on its target — without affecting cell growth or survival.

The most significant changes occurred in a gene called RbAp48, whose expression declined steadily with aging across the study subjects.

In these cases, drug exposure caused significant changes in tumor cells» gene expression profile but had no lasting physical effecIn these cases, drug exposure caused significant changes in tumor cells» gene expression profile but had no lasting physical effecin tumor cells» gene expression profile but had no lasting physical effect.

In order to find non-linear differential expression we developed a method to identify significant changes between different post-mortem intervals.

Proteomic analysis to profile protein abundance resulted in the identification and relative quantification for 912 proteins with two or more unique peptides and 86 proteins with significant abundance changes after treatment with the neurotoxins, while microarray analyses to profile gene expression revealed 181 genes with significant changes in mRNA after treatment.

Our data suggest that changes in the expression of genes associated with drug resistance and cancer cell «stemness», induced by treatment with MIA - 602, lead to a significant reduction in the efflux capacity of drug resistant cells.

Pair-wise comparisons (FDR < 0.05, > 1.5-fold expression levels) were performed between the following populations of cells to reveal non-redundant, significant changes in gene expression.

Significant changes in gene expression between anoikis - resistant and total population cells are shown in Table 1.

So while scrolling through Fashion Week photos online, it's healthy to remember that what's significant about fashion blogging isn't just the opportunity it provides to show off Valentino pumps or rave about Phoebe Philo, but also its role as a bellwether for the changing nature of consumerism and self - expression in the digital era.

There's no significant change in the understanding of climate change or global warming which continue to be valid expressions (while CAGW is just a concept invented by skeptics to use as they like and in a way that does not reflect main stream views).

The National Oceanic and Atmospheric Administration should play a significant role in the Obama administration as a key agency on climate change and oceans — with freedom of scientific expression ensured.

In each of the above areas — entry restrictions, advertising and paralegals — the courts did ultimately inspire, if not dictate, significant change: citizenship requirements were ultimately deemed invalid by the Supreme Court of Canada in Andrews, advertising restrictions were liberalized in the context of a series of post-Charter cases finding freedom of expression protections applied to commercial speech and professional advertising, and paralegal regulation has been reviewed in provinces across Canada following the courts» attention to the issuIn each of the above areas — entry restrictions, advertising and paralegals — the courts did ultimately inspire, if not dictate, significant change: citizenship requirements were ultimately deemed invalid by the Supreme Court of Canada in Andrews, advertising restrictions were liberalized in the context of a series of post-Charter cases finding freedom of expression protections applied to commercial speech and professional advertising, and paralegal regulation has been reviewed in provinces across Canada following the courts» attention to the issuin Andrews, advertising restrictions were liberalized in the context of a series of post-Charter cases finding freedom of expression protections applied to commercial speech and professional advertising, and paralegal regulation has been reviewed in provinces across Canada following the courts» attention to the issuin the context of a series of post-Charter cases finding freedom of expression protections applied to commercial speech and professional advertising, and paralegal regulation has been reviewed in provinces across Canada following the courts» attention to the issuin provinces across Canada following the courts» attention to the issue.

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