Sentences with phrase «significant cognitive effects»

Since whole - brain radiation is associated with significant cognitive effects and the use of additional radiation therapy for progression is common in this population, the Yale researchers suspect that patients with the ALK mutation would benefit from radiation focused on individual metastases.

Not exact matches

Studies of the Nurse Family Partnership model followed children to 6 years and found significant program effects on language and cognitive functioning as well as fewer behaviour problems in a randomized controlled trial study.24 In addition, more recent evaluations of Healthy Families America have shown small, but favourable effects on young children's development.25, 26

«This well - designed set of experiments shows that chronic THC pretreatment appears to restore a significant level of diminished cognitive performance in older mice, while corroborating the opposite effect among young mice,» wrote Susan Weiss, director of the Division of Extramural Research at the National Institute on Drug Abuse, who was not involved in the study, in an e-mail.

It is critical for physicians to monitor these secondary tissue damages, as they are frequently the origin of significant long - term effects, including brain damage, cognitive deficits, psychosocial / behavioral / emotional changes, bodily damage and biochemical changes at the cellular level.

To begin to address such questions, Chang showed men pictures of women and tested for statistically significant effects of those pictures on men's attitudes about war and on their cognitive processes related to war.

While the treatment did have some favorable effects, in the main measure of outcome — measured with a cognitive test called the Alzheimer's Disease Assessment Scale - cognitive subscale — the researchers did not observe any statistically significant benefit compared with placebo.

Furthermore, the study found that cognitive intrusion — recurrent thoughts about the stressor — was a significant and key mediator, accounting for 69 percent of the total effect of stress exposure on insomnia.

According to Bonn - Miller, a number of products also contained a significant amount of THC — the chemical compound in cannabis responsible for making a person feel «high» — which has been shown cause cognitive impairment and other adverse health effects.

The clearest effect can be seen in the functional networks of the frontal lobe, especially significant to cognitive functions.

In fact, none of the other ingredients present in energy drinks and in the amounts in a can of energy drink actually produces a significant effect on physical or cognitive performance.

She said the 1.5 percentage - point difference in survival rates between women who got chemo and the ones who didn't was not statistically significant, especially considering the side effects of chemo, which can include fatigue, cognitive impairment and a prolonged disruption in schedule.

Therefore, while treatment with J147 enhanced the cognitive ability of the huAPP / PS1 mice, it had no significant effect on plaque load but produced a significant reduction of soluble Aβ levels.

The effect is considered a predecessor for dementia, along with other significant signs of cognitive decline.

The American Psychological Association has concluded that caffeine has significant effects on psychomotor and cognitive performance, psychological well - being, blood pressure and athletic performance.

Besides, «unlike medication, which was found to have no significant effect on mild cognitive impairment, «the exercise program has numerous other benefits (of which we're all aware).

One study that focused specifically on the relationship between exercise intensity and BDNF concentration levels found no significant changes in BDNF levels after the low - intensity exercise, but significantly elevated BDNF levels after high - intensity exercise.13 Ferris, L.T., et al. «The Effect of Burst Exercise on Serum Brain - Derived Neurotrophic Factor Levels and Cognitive Function,» Medicine and... continue

In terms of an actual diagnosis of mild cognitive impairment, however, the researchers only identified 37 people who developed that condition during the study, and the diets didn't have a significant effect on the risk for that diagnosis.

In the review, Mindfulness - Based Interventions for Improving Cognition, Academic Achievement, Behavior and Socioemotional Functioning of Primary and Secondary Students, the authors found that mindfulness - based interventions have a statistically significant positive effect on cognitive and socioemotional processes for students, but that they do not improve behavior or academic performance.

In fact, there were two significant negative effects shown in cognitive skills for the three - year - old cohort, meaning the control group that did not participate in any preschool program had higher cognitive scores.

PANSS negative Cognitive therapy did not have a significant effect on negative symptoms at any follow - up time: estimated improvement − 1.02 (95 % CI − 2.35 to 0.30) compared with the treatment as usual group.

Controls for family transitions had little impact on estimates of the effects of family poverty: all poverty variables remain significantly associated with cognitive functioning at the age of 5 years, except for transient experiences of poverty at the age of 3 years only (npn), which showed no significant risk effect on pattern construction.

Cannabis use can be a significant contributor to poor mental health, particularly when it begins at a young age.4, 5 The adverse mental health effects of cannabis use in the general population are increasingly recognised, including anxiety, depression, 6 — 8 psychotic disorders, 4, 9 — 12 dependence6, 7, 13 withdrawal14, 15 and cognitive impairment.16, 17 Starting to use cannabis before age 15 is associated with an increased likelihood of developing later psychotic disorders, increased risk of dependence, other drug use, and poor educational and psychosocial outcomes.5

There were no statistically significant effects on child cognitive development, internalising behaviour or externalising behaviour at post-intervention; however, internalising and externalising behaviours were marginally significant and may have reached statistical significance with a larger sample.

There were no significant effects on cognitive development (d = 0.13; 95 % CI − 0.08 to 0.41), internalising behaviour (d = 0.16; 95 % CI − 0.03 to 0.33) or externalising behaviour (d = 0.16; 95 % CI − 0.01 to 0.30) post-intervention.

The meta - analyses showed the most pronounced effect sizes for parent — child interaction and maternal sensitivity, whereas the effects on child behaviour and cognitive development were either small or not significant; however, small effect sizes can have meaningful impact on population - level outcomes.60 The non-significant outcomes for internalising and externalising behaviours were also small, but may be clinically relevant for large, at - risk populations.

Adding indicators of living circumstances reduces the association between poverty and cognitive functioning, although associations between persistent and cumulative poverty, as well as early poverty at the age of 9 months remain significant in addition and above the effects of the other variables included in the model.

Researchers of cognitive psychology in Quebec, Canada exploring the effect of stress on our brains have found an important link: numerous studies have demonstrated significant connections between stress, anxiety, distractibility, and the functioning of short term memory.

Monson and coauthors conducted a randomized controlled trial of the effects of cognitive - behavioral conjoint therapy delivered to patients with PTSD and their significant others to simultaneously treat PTSD symptoms and enhance relationship satisfaction, compared with a wait - list condition.

Our intention to treat analysis, however, showed that even with the most conservative estimate of the effects of selective withdrawal there was still a significant benefit of cognitive behaviour therapy.

The effect of cognitive behaviour therapy was still found to be significant when these trials were excluded, with remission rates in an intention to treat analysis of 105/161 in the cognitive behaviour therapy group and 69/152 in the comparison conditions.

These effects not only determine physical health but also emotional and cognitive development.3 — 5 Maternal separation and nonbonding have a significant impact on early brain development, which places children at risk of emotional and cognitive deficit.

The most recent follow - up study reported associations between duration of breastfeeding and childhood cognitive ability and academic achievement extending from 8 to 18 years in a New Zealand cohort of 1000 children.19 This study found that these effects were significant after controlling for measures of social and family history, including maternal age, education, SES, marital status, smoking during pregnancy, family living conditions, and family income, and measures of perinatal factors, including gender, birth weight, child's estimated gestational age, and birth order in the family.

In both the childhood and young adult (age - 18) follow - ups, the trial found statistically - significant effects on cognitive ability and reading and / or math achievement for a key subgroup (but not for the full sample).

Converging evidence reveals a significant impact of childhood trauma on neurobiological development (in terms of brain structure and function), psychological processes, hormonal and cognitive functioning, which may underlie the effect of childhood trauma on later psychological functioning.

Analyses of findings from an earlier intensive child development program for low birth weight children and their parents (the Infant Health and Development Program) suggest that the cognitive effects for the children were mediated through the effects on parents, and the effects on parents accounted for between 20 and 50 % of the child effects.10 A recent analysis of the Chicago Child Parent Centers, an early education program with a parent support component, examined the factors responsible for the program's significant long - term effects on increasing rates of school completion and decreasing rates of juvenile arrest.11 The authors conducted analyses to test alternative hypotheses about the pathways from the short - term significant effects on children's educational achievement at the end of preschool to these long - term effects, including (a) that the cognitive and language stimulation children experienced in the centres led to a sustained cognitive advantage that produced the long - term effects on the students» behaviour; or (b) that the enhanced parenting practices, attitudes, expectations and involvement in children's education that occurred early in the program led to sustained changes in the home environments that made them more supportive of school achievement and behavioural norms, which in turn produced the long - term effects on the students» behaviour.

Pretest to 30 - day follow - up analyses indicated significant treatment effects on parent - reported discipline style (Parenting Scale, Adolescent version), child behavior (Eyberg Child Behavior Inventory), and on social cognitive theory constructs of intentions and self - efficacy.

For the cognitive and externalizing outcomes, the results were not consistent with causal effects; when comparing differentially exposed siblings none of the associations remained significant.

Our finding that the severity of depressive symptoms was a significant but relatively smaller contributor to physical disability in this sample (after controlling for the possible effects of age, sex and duration of pain) is consistent with findings of some previous studies of patients with chronic pain, but not with some treatment studies, which found that depression level contributed to less significant improvement in pain - related disability.11, 27 It is not surprising that cognitive, pain and behavioural variables accounted for more physical disability than depressive symptoms but it is notable that social support (as measured by the MPI), sense of control over life, and catastrophising did not significantly contribute to physical disability.

We also found significant pretest by condition interaction effects on teacher reports of skills associated with executive function, including inhibitory control and shift (cognitive flexibility), and on teacher reported internalizing and externalizing behavior.

Stress - reactive rumination («SR - rumination») was related to depressive symptoms, independently of negative cognitive style («NCS») or stressors, of which main effects were significant in both boys and girls.