Not exact matches
The women
in the study (there were only eight) reported a
significant decrease in milk
production after a single dose of Sudafed.
In contrast, in cultures treated with X4 - ZFNs viral titers steadily decreased after peak viremia while cell growth remained exponential suggesting there was not significant viral production (data not shown
In contrast,
in cultures treated with X4 - ZFNs viral titers steadily decreased after peak viremia while cell growth remained exponential suggesting there was not significant viral production (data not shown
in cultures treated with X4 - ZFNs viral titers steadily
decreased after peak viremia while cell growth remained exponential suggesting there was not
significant viral
production (data not shown).
Fall and fall - related injuries are common among elderly individuals, with
significant socioeconomic consequences for individuals and society, and women are affected more than men due to the
decrease in female sex hormone
production.»
These changes were accompanied by severe EC damage,
decreased E-cadherin RNA level, elevated IFN - gamma
in splenocyte culture supernatant, and
production of
significant IgM antibody against intestinal microbiota.
Explains Dr. Michael Seidman, Tinnitus Center
in Bloomfield, Michigan2
in his article, «Medicines to Treat the Inner Ear»: «
Decreased blood supply causes
significant stress to the nerve tissue (of the inner ear) by causing the
production of free radicals.
For example, KBs were recently reported to act as neuroprotective agents by raising ATP levels and reducing the
production of reactive oxygen species
in neurological tissues, 80 together with increased mitochondrial biogenesis, which may help to enhance the regulation of synaptic function.80 Moreover, the increased synthesis of polyunsaturated fatty acids stimulated by a KD may have a role in the regulation of neuronal membrane excitability: it has been demonstrated, for example, that polyunsaturated fatty acids modulate the excitability of neurons by blocking voltage-gated sodium channels.81 Another possibility is that by reducing glucose metabolism, ketogenic diets may activate anticonvulsant mechanisms, as has been reported in a rat model.82 In addition, caloric restriction per se has been suggested to exert neuroprotective effects, including improved mitochondrial function, decreased oxidative stress and apoptosis, and inhibition of proinflammatory mediators, such as the cytokines tumour necrosis factor - α and interleukins.83 Although promising data have been collected (see below), at the present time the real clinical benefits of ketogenic diets in most neurological diseases remain largely speculative and uncertain, with the significant exception of its use in the treatment of convulsion disease
in neurological tissues, 80 together with increased mitochondrial biogenesis, which may help to enhance the regulation of synaptic function.80 Moreover, the increased synthesis of polyunsaturated fatty acids stimulated by a KD may have a role
in the regulation of neuronal membrane excitability: it has been demonstrated, for example, that polyunsaturated fatty acids modulate the excitability of neurons by blocking voltage-gated sodium channels.81 Another possibility is that by reducing glucose metabolism, ketogenic diets may activate anticonvulsant mechanisms, as has been reported in a rat model.82 In addition, caloric restriction per se has been suggested to exert neuroprotective effects, including improved mitochondrial function, decreased oxidative stress and apoptosis, and inhibition of proinflammatory mediators, such as the cytokines tumour necrosis factor - α and interleukins.83 Although promising data have been collected (see below), at the present time the real clinical benefits of ketogenic diets in most neurological diseases remain largely speculative and uncertain, with the significant exception of its use in the treatment of convulsion disease
in the regulation of neuronal membrane excitability: it has been demonstrated, for example, that polyunsaturated fatty acids modulate the excitability of neurons by blocking voltage-gated sodium channels.81 Another possibility is that by reducing glucose metabolism, ketogenic diets may activate anticonvulsant mechanisms, as has been reported
in a rat model.82 In addition, caloric restriction per se has been suggested to exert neuroprotective effects, including improved mitochondrial function, decreased oxidative stress and apoptosis, and inhibition of proinflammatory mediators, such as the cytokines tumour necrosis factor - α and interleukins.83 Although promising data have been collected (see below), at the present time the real clinical benefits of ketogenic diets in most neurological diseases remain largely speculative and uncertain, with the significant exception of its use in the treatment of convulsion disease
in a rat model.82
In addition, caloric restriction per se has been suggested to exert neuroprotective effects, including improved mitochondrial function, decreased oxidative stress and apoptosis, and inhibition of proinflammatory mediators, such as the cytokines tumour necrosis factor - α and interleukins.83 Although promising data have been collected (see below), at the present time the real clinical benefits of ketogenic diets in most neurological diseases remain largely speculative and uncertain, with the significant exception of its use in the treatment of convulsion disease
In addition, caloric restriction per se has been suggested to exert neuroprotective effects, including improved mitochondrial function,
decreased oxidative stress and apoptosis, and inhibition of proinflammatory mediators, such as the cytokines tumour necrosis factor - α and interleukins.83 Although promising data have been collected (see below), at the present time the real clinical benefits of ketogenic diets
in most neurological diseases remain largely speculative and uncertain, with the significant exception of its use in the treatment of convulsion disease
in most neurological diseases remain largely speculative and uncertain, with the
significant exception of its use
in the treatment of convulsion disease
in the treatment of convulsion diseases.
While breast milk
production in this study increased with increased fluid intake and
decreased with
decreased intake, neither change was statistically
significant.
One of the negative outcomes of menopause is a
significant decrease in estrogen
production that,
in turn, leads to thinning and dryness of vaginal tissue and, as a result, makes penetration more painful.
While Saudi Arabia remains a
significant unknown factor
in the near term pricing of oil because of its ability to substantially increase or
decrease production, longer term factors,
in our judgment, remain very favorable.
The therapeutic dotential of dietary precursor modulation by a fish - oil - supplemented diet (n - 3 fatty acids), such as eicosapentaenoic acid (C20: 5,n - 3) and docosahexaenoic acid (C22: 6,n - 3)
in the therapy of ulcerative colitis has been shown to result
in a 35 % to 50 %
decrease in neutrophil
production of LTB4.28
Significant improvement in symptoms and histologic appearance of the rectal mucosa has been observed in several small series of patients with Crohn's disease and ulcerative colitis given fish oil at 3 to 4 g daily for 2 to 6 months in uncontrolled studies.29 However, a larger, randomized, double - blind trial comprising 96 patients with ulcerative colitis failed to reveal any benefit in remission maintenance or treatment of relapse on 4.5 g of eicosapentaenoic acid daily, despite a significant reduction in LTB4 synthesis by blood peripheral polymorphonuclear cells.30 It should be emphasized, however, that the anti-inflammatory actions of the fish oils, in addition to inhibition of LTB4, include suppression of IL - 1 and platelet activating factor synthesis and scavenging of free oxygen radicals.30 The impact of increased lipid peroxidation after fish oil supplementation should be considered when altering the n - 6: n - 3 fatty acid ratio.31 Antioxidant supplementation may be able to counteract the potentially adverse effects of n - 3 f
Significant improvement
in symptoms and histologic appearance of the rectal mucosa has been observed
in several small series of patients with Crohn's disease and ulcerative colitis given fish oil at 3 to 4 g daily for 2 to 6 months
in uncontrolled studies.29 However, a larger, randomized, double - blind trial comprising 96 patients with ulcerative colitis failed to reveal any benefit
in remission maintenance or treatment of relapse on 4.5 g of eicosapentaenoic acid daily, despite a
significant reduction in LTB4 synthesis by blood peripheral polymorphonuclear cells.30 It should be emphasized, however, that the anti-inflammatory actions of the fish oils, in addition to inhibition of LTB4, include suppression of IL - 1 and platelet activating factor synthesis and scavenging of free oxygen radicals.30 The impact of increased lipid peroxidation after fish oil supplementation should be considered when altering the n - 6: n - 3 fatty acid ratio.31 Antioxidant supplementation may be able to counteract the potentially adverse effects of n - 3 f
significant reduction
in LTB4 synthesis by blood peripheral polymorphonuclear cells.30 It should be emphasized, however, that the anti-inflammatory actions of the fish oils,
in addition to inhibition of LTB4, include suppression of IL - 1 and platelet activating factor synthesis and scavenging of free oxygen radicals.30 The impact of increased lipid peroxidation after fish oil supplementation should be considered when altering the n - 6: n - 3 fatty acid ratio.31 Antioxidant supplementation may be able to counteract the potentially adverse effects of n - 3 fatty acids.
Most
significant is the 24 %
decrease of coal use
in electric generation and the 12 %
decrease in crude oil
production.
The
significant decrease in coal used to produce electricity can be attributed to three factors: overall lower electricity demand; a fuel shift to natural gas; and an offset created by more wind power
production, according to Simon.
say it has been predicted that «the average temperature
in the semiarid northwest portion of China
in 2050 will be 2.2 °C higher than it was
in 2002,» and they report that based on the observed results of their study, this increase
in temperature «will lead to a
significant change
in the growth stages and water use of winter wheat,» such that «crop yields at both high and low altitudes will likely increase,» by 2.6 % at low altitudes and 6.0 % at high altitudes... Even without the benefits of the aerial fertilization effect and the anti-transpiration effect of the ongoing rise
in the air's CO2 content, the increase
in temperature that is predicted by climate models for the year 2050, if it ever comes to pass, will likely lead to increases
in winter wheat
production in the northwestern part of China, not the
decreases that climate alarmists routinely predict.»