Not exact matches
In both species,
significant reductions in
epigenetic drift were observed, such that age - related
changes in methylation in old animals on the calorie - restricted diets were comparable to those of young animals.
With these improved tools, we can now reveal
epigenetic changes in cancers, which may well be just as
significant as genetic mutations.»
In these canine cells we induced a morphological
change similar to what happens in cancer progression and we have seen displayed
significant alterations in the modulation of genes, called
epigenetic lesions,» says Manel Esteller.
The new compound, Corin, specifically targets these
epigenetic changes in cells and could therefore provide
significant improvements in patients without unwanted side effects.